Regulation of NK Cell Functions Through Interaction of the CD94/NKG2 Receptors with the Nonclassical Class I Molecule HLA-E

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

NK CELL RECEPTORS

1998 • 1,666 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

1998 • 892 citations

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

1998 • 706 citations

Association of DAP12 with Activating CD94/NKG2C NK Cell Receptors

1998 • 528 citations

HLA-E Surface Expression Depends on Binding of TAP-Dependent Peptides Derived from Certain HLA Class I Signal Sequences

1998 • 495 citations

The human major histocompatibility complex class Ib molecule HLA‐E binds signal sequence‐derived peptides with primary anchor residues at positions 2 and 9

1997 • 489 citations

Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.

1996 • 441 citations

Identification of a tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen

1994 • 275 citations

TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide

1998 • 275 citations

The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules

1997 • 271 citations

Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells.

1997 • 260 citations

NKG2A Complexed with CD94 Defines a Novel Inhibitory Natural Killer Cell Receptor

1997 • 252 citations

Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases

1998 • 236 citations

Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C.

1997 • 229 citations

Structural Features Impose Tight Peptide Binding Specificity in the Nonclassical MHC Molecule HLA-E

1998 • 206 citations

CD94 and a Novel Associated Protein (94AP) Form a NK Cell Receptor Involved in the Recognition of HLA-A, HLA-B, and HLA-C Allotypes

1996 • 187 citations

The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1.

1997 • 159 citations

CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.

1997 • 140 citations

CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies

1996 • 133 citations

How to recongnize a foreign submarine

1997 • 124 citations

Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants

1998 • 122 citations

Signal Sequence Processing in Rough Microsomes

1995 • 111 citations

The activating form of CD94 receptor complex: CD94 covalently associated with the Kp39 protein that represents the product of the NKG2-C gene

1998 • 98 citations

HLA‐G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex

1997 • 90 citations

Major Histocompatibility Complex Class I Molecules Modulate Activation Threshold and Early Signaling of T Cell Antigen Receptor–γ/δ Stimulated by Nonpeptidic Ligands

1997 • 87 citations

The MHC-E Locus Is the Most Well Conserved of All Known Primate Class I Histocompatibility Genes

1998 • 85 citations

Regulation through inhibitory receptors: Lessons from natural killer cells

1997 • 76 citations

Impaired intracellular transport and cell surface expression of nonpolymorphic HLA-E: evidence for inefficient peptide binding.

1992 • 61 citations