How to recongnize a foreign submarine

In search of the ‘missing self’: MHC molecules and NK cell recognition

1990 • 2,600 citations

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

1986 • 2,102 citations

„Natural”︁ killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype

1975 • 1,743 citations

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity

1975 • 1,308 citations

MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells

1992 • 805 citations

Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and antagonistic inhibition of susceptibility of target cells to lysis.

1978 • 744 citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

1993 • 537 citations

Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts

1977 • 467 citations

Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice

1991 • 419 citations

PECULIAR IMMUNOBIOLOGY OF BONE MARROW ALLOGRAFTS

1971 • 349 citations

NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

1994 • 343 citations

Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes.

1989 • 241 citations

Generation of Allospecific Natural Killer Cells by Stimulation Across a Polymorphism of HLA-C

1993 • 241 citations

Genetic variation of in vitro cytolytic activity and in vivo rejection potential of non‐immunized semi‐syngeneic mice against a mouse lymphoma line

1975 • 230 citations

Prevention of Allogeneic Bone Marrow Graft Rejection by H-2 Transgene in Donor Mice

1989 • 218 citations

Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).

1992 • 218 citations

Histocompatibility Genes of the Mouse. II. Production and Analysis of Isogenic Resistant Lines<xref ref-type="fn" rid="FN1">2</xref>

1958 • 194 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

Differential expression of H–2 gene products in tumour cells is associated with their metastatogenic properties

1980 • 146 citations

Natural killer cells mediate lysis of embryonal carcinoma cells lacking MHC

1980 • 142 citations

Natural killer susceptibility of human cells may be regulated by genes in the HLA region on chromosome 6.

1986 • 141 citations

Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice.

1988 • 116 citations

Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.

1990 • 92 citations

The Rapid Elimination of Allogeneic Lymphocytes: Relationship to Established Mechanisms of Immunity and to Lymphocyte Traffic

1983 • 79 citations

ROLE OF TARGET HISTOCOMPATIBILITY ANTIGENS IN REGULATION OF NATURAL KILLER ACTIVITY: A REEVALUATION AND A HYPOTHESIS11Based on a doctoral thesis at The Karolinska Institute, supported by grants from the Karolinska Institute, The Swedish Cancer Society, The National Cancer Institute (US DHEW) and The Engwall Foundation.

1985 • 76 citations

Modulation of Sensitivity to Natural Killer Cell Lysis After In Vitro Explantation of a Mouse Lymphoma<xref ref-type="fn" rid="FN2">2</xref>

1978 • 69 citations

Colony Specificity in the Colonial Tunicate Botryllus and the Origins of Vertebrate Immunity

1982 • 57 citations

MHC gene control of the natural killer system at the level of the target and the host.

1991 • 36 citations

Recognition structures determined by the H-2 complex.

1976 • 34 citations

Specific immunorecognition by histocompatibility markers: The original polymorphic system of immunoreactivity characteristic of all multicellular animals

1977 • 26 citations

On the phylogenetic origin of the immune system a hypothesis

1977 • 21 citations