Metabolic responses to interleukin-1

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis*

1986 • 2,235 citations

Interleukin-1 Stimulates the Secretion of Hypothalamic Corticotropin-Releasing Factor

1987 • 1,512 citations

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1990 • 1,362 citations

Corticotropin-Releasing Factor-Producing Neurons in the Rat Activated by Interleukin-1

1987 • 1,152 citations

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

1990 • 1,095 citations

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

Interleukin-1 Immunoreactive Innervation of the Human Hypothalamus

1988 • 771 citations

The Immune-Hypothalamic-Pituitary-Adrenal Axis*

1989 • 671 citations

Lipocortin and the mechanism of action of the glucocorticoids

1988 • 499 citations

BROWN ADIPOSE TISSUE.

1965 • 466 citations

Visualization and characterization of interleukin 1 receptors in brain.

1987 • 451 citations

The cell surface receptors for interleukin-1α and interleukin-1β are identical

1986 • 422 citations

THE IMMEDIATE CAUSES OF DEATH IN CANCER

1932 • 418 citations

Neural Modulation of Immunity

1985 • 353 citations

Immunoreactive interleukin-1β localization in the rat forebrain

1990 • 343 citations

The disturbance of metabolism produced by bony and non-bony injury, with notes on certain abnormal conditions of bone

1930 • 334 citations

Functions and mechanisms of interleukin 1 in the brain

1991 • 325 citations

Systematic interleukin-1 administration stimulates hypothalamic norepinephrine metabolism parallelling the increased plasma corticosterone

1988 • 300 citations

Synthesis of interleukin 1/endogenous pyrogen in the brain of endotoxin-treated mice: a step in fever induction?

1984 • 279 citations

Immobilization stress induces interleukin-1β mRNA in the rat hypothalamus

1991 • 258 citations

Effects of corticotropin-releasing factor on food intake and brown adipose tissue thermogenesis in rats

1988 • 255 citations

Role of interleukin 6 in fever in rats

1990 • 231 citations

Macrophage Inflammatory Protein-1: a Prostaglandin-Independent Endogenous Pyrogen

1989 • 222 citations

Effects of serotonergic agonists and antagonists on corticotropin-releasing hormone secretion by explanted rat hypothalami

1989 • 217 citations

Mammalian Thermogenesis

1983 • 216 citations

Interleukin 1 receptor blockade attenuates the host inflammatory response.

1990 • 216 citations

Central effects of CRF on metabolism and energy balance

1990 • 192 citations

Occurrence of interleukin-1 in cerebrospinal fluid of the conscious cat

1988 • 178 citations

The Immune Logical Brain

1987 • 175 citations

Identification of a high-affinity receptor for interleukin-1 beta in rat brain

1988 • 160 citations

Interleukin-6 is a centrally acting endogenous pyrogen in the rat

1991 • 152 citations

Induction of interleukin-1β mRNA in adult rat brain

1991 • 136 citations

CRF is involved in the pyrogenic and thermogenic effects of interleukin 1 beta in the rat

1989 • 134 citations

Stimulation of ACTH release by human interleukin-1β, but not by interleukin-1α, in conscious, freely-moving rats

1987 • 115 citations

Activation of brown fat thermogenesis in response to central injection of corticotropin releasing hormone in the rat

1987 • 113 citations

Pyrogenic and thermogenic effects of interleukin 1 beta in the rat

1989 • 111 citations

Energy Balance, Diet-Induced Thermogenesis and Brown Adipose Tissue in Lean and Obese (fa/fa) Zucker Rats after Adrenalectomy

1983 • 111 citations

Endotoxin-Induced Release of Interleukin-6 from Rat Medial Basal Hypothalami*

1990 • 107 citations

The effect of adrenalectomy on GDP binding to brown-adipose-tissue mitochondria of obese rats

1982 • 102 citations

Involvement of corticotrophin releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds

1991 • 99 citations

Biological relevance of lipocortins and related proteins as inhibitors of phospholipase A2

1989 • 97 citations

Circulating interleukin 1 and tumor necrosis factor during inflammation

1987 • 87 citations

Effects of corticotropin releasing factor on genetically obese (fatty) rats

1989 • 84 citations

Multiple control of fever production in the central nervous system of rabbits.

1988 • 80 citations

Arachidonic Acid Metabolites Modulate Rat Hypothalamic Corticotropin-Releasing Hormone Secretion in vitro

1989 • 80 citations

Detection of interleukin 1 alpha and 1 beta in rabbit tissues during endotoxemia using sensitive radioimmunoassays

1991 • 78 citations

The Neurobiology of Fever: Thoughts on Recent Developments

1987 • 77 citations

Central activation of thermogenesis and fever by interleukin-1β and interleukin-1α involves different mechanisms

1989 • 74 citations

Differential binding of IL‐ 1α and IL‐ 1β to receptors on B and T cells

1989 • 70 citations

Effect of diet and fenfluramine on thermogenesis in the rat: possible involvement of serotonergic mechanisms.

1987 • 68 citations

Central effects of TNF α on thermogenesis and fever in the rat

1988 • 66 citations

Thermogenic Effects of the Antiglucocorticoid RU-486 in the Rat: Involvement of Corticotropin-Releasing Factor and Sympathetic Activation of Brown Adipose Tissue*

1989 • 62 citations

Neural Mechanisms in the Pyrogenic and Acute-Phase Responses to Interleukin-1

1988 • 58 citations

Corticotropin-releasing factor (CRF) — a review

1986 • 57 citations

Mechanisms of the pyrogenic actions of cytokines.

1990 • 52 citations

Basic and clinical aspects

1996 • 51 citations

Localization of immunoreactive lipocortin-1 in the brain and pituitary gland of the rat. Effects of adrenalectomy, dexamethasone and colchicine treatment

1991 • 47 citations

Cancer Cachexia

1988 • 46 citations

Central Activation of Thermogenesis by Prostaglandins: Dependence on CRF

1990 • 45 citations

The CRFs and their control: Chemistry, physiology and clinical implications

1985 • 43 citations

Increased type II glucocorticoid-receptor numbers and glucocorticoid-sensitive enzyme activities in the brain of the obese Zucker rat

1990 • 41 citations

Vasopressin and fever: evidence supporting the existence of an endogenous antipyretic system in the brain

1987 • 40 citations

Antipyretic effect of centrally administered CRF

1984 • 38 citations

Central control of brown adipose tissue

1989 • 37 citations

Central Actions of Interleukin-8 in the Rat are Independent of Prostaglandins

1990 • 33 citations

Fever Response in Old and Young Mice After Injection of Interleukin

1988 • 33 citations

Central actions of CRF on thermogenesis are mediated by pro-opiomelanocortin products

1991 • 33 citations

Impaired effects of interleukin-1 beta on fever and thermogenesis in genetically obese rats.

1989 • 31 citations

Acute central effects of interleukin-6 on body temperature, thermogenesis and food intake in the rat

1989 • 28 citations

Monokines, lymphokines, and the brain.

1989 • 23 citations

Body temperature changes during inflammation: their mediation and nutritional significance

1989 • 23 citations

Mechanisms of early and late hypermetabolism and fever after localized tissue injury in rats

1991 • 21 citations

Whither brown fat?

1986 • 20 citations

Lipocortins, mediators of the anti-inflammatory actions of corticosteroids?

1989 • 17 citations

Corticosteroid inhibition of thermogenesis in obese animals

1989 • 14 citations

Effect of Age on the Febrile Response of Rats to Endogenous Pyrogen

1985 • 13 citations

Age-related differences in the febrile response of the New Zealand White rabbit to endotoxin

1981 • 13 citations

Adrenalectomy reverses the impaired pyrogenic responses to interleukin-beta in obese Zucker rats.

1990 • 11 citations

Central actions of interleukin-1β on fever and thermogenesis

1989 • 7 citations

Thermogenesis and BAT activity in hypophysectomized rats with and without corticotropin replacement

1985 • 7 citations

Hypermetabolism in Trauma

1983 • 7 citations

Effect of hypophysectomy on energy balance and brown fat activity in obese Zucker rats

1988 • 6 citations

Interferon-γ down-regulates membrane adenylate cyclase activity of a murine macrophage-like cell line (P388D1)

1989 • 5 citations

Changes in plasma interleukin-6 during experimentally-induced fever in normal humans

1989 • 2 citations

Thermogenesis in Obesity and Cachexia

1990 • 1 citations

Deleted Work

1955 • 0 citations