Arachidonic acid metabolism in normal and hypereosinophilic syndrome human eosinophils: generation of leukotrienes B4, C4, D4 and 15-lipoxygenase products.

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature.

1975 • 1,242 citations

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

1976 • 1,012 citations

The Idiopathic Hypereosinophilic Syndrome

1982 • 842 citations

Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica

1980 • 615 citations

Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds.

1979 • 556 citations

A New Method for the Purification of Human Eosinophils and Neutrophils, and a Comparison of the Ability of These Cells to Damage Schistosomula of Schistosoma Mansoni

1979 • 366 citations

Phospholipid precursors of prostaglandins

1968 • 333 citations

Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid.

1980 • 330 citations

Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes

1978 • 306 citations

Release and metabolism of arachidonic acid in human neutrophils.

1981 • 281 citations

Mediators of Immediate Hypersensitivity Derived from Arachidonic Acid

1980 • 207 citations

Leukotriene generation by eosinophils.

1982 • 196 citations

Initiation of phospholipase A2 activity in human platelets by the calcium ion ionophore A23187

1977 • 178 citations

Patterns of fatty acid release from endogenous substrates by human platelet homogenates and membranes.

1975 • 178 citations

Regulation of arachidonic acid metabolism by macrophage activation.

1982 • 176 citations

The action of prostaglandin synthetase on 2-arachidonyl-lecithin

1968 • 160 citations

Eosinophil peroxidase-mediated inactivation of leukotrienes B4, C4, and D4.

1982 • 149 citations

Selective feed-back inhibition of the 5-lipoxygenation of arachidonic acid in human T-lymphocytes

1981 • 146 citations

Enhanced Helminthotoxic Capacity of Eosinophils from Patients with Eosinophilia

1980 • 139 citations

The regulation of human eosinophil function by endogenous mono-hydroxy-eicosatetraenoic acids (HETEs).

1980 • 138 citations

Comparison of Human Eosinophils from Normals and Patients with Eosinophilia

1980 • 134 citations

Ionophores stimulate prostaglandin and thromboxane biosynthesis

1977 • 133 citations

New role for 15-hydroxyeicosatetraenoic acid. Activator of leukotriene biosynthesis in PT-18 mast/basophil cells.

1982 • 109 citations

Formation of a novel dihydroxy acid from arachidonic acid by lipoxygenase-catalyzed double oxygenation in rat mononuclear cells and human leukocytes.

1982 • 101 citations

Release of arachidonic acid from human lymphocytes in response to mitogenic lectins.

1979 • 91 citations

Human monocytes synthesize eicosanoids from T lymphocyte-derived arachidonic acid

1982 • 70 citations

EFFECTS OF MODULATORS OF ARACHIDONIC ACID METABOLISM ON THE SYNTHESIS AND RELEASE OF SLOW‐REACTING SUBSTANCE OF ANAPHYLAXIS

1979 • 64 citations

Identification of lipoxygenase products from arachidonic acid metabolism in stimulated murine eosinophils

1983 • 45 citations

A review of recent contributions on biologically active products of arachidonate conversion

1982 • 38 citations

Inhibition of thrombin-induced platelet arachidonic acid release by 15-hydroperoxy-arachidonic acid

1981 • 26 citations

Arachidonic acid metabolism of the murine eosinophil. II. Involvement of the lipoxygenase pathway in the response to the lymphokine eosinophil stimulation promoter.

1982 • 22 citations

The effect of substrate availability on the metabolism of arachidonic acid in human platelets

1981 • 12 citations