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Predicting ADME properties and side effects: the BioPrint approach.

Data up to Jan 2025

Published2003
Citations176
References28

Total Citations Per Year

Abstract

References (28)

Handbook of Molecular Descriptors

2000 • 4,065 citations

Prediction of Drug Absorption Using Multivariate Statistics

2000 • 1,522 citations

Caco-2 monolayers in experimental and theoretical predictions of drug transport1PII of original article: S0169-409X(96)00415-2. The article was originally published in Advanced Drug Delivery Reviews 22 (1996) 67–84.1

2001 • 1,479 citations

Application of Genetic Function Approximation to Quantitative Structure-Activity Relationships and Quantitative Structure-Property Relationships

1994 • 960 citations

Neighborhood Behavior: A Useful Concept for Validation of “Molecular Diversity” Descriptors

1996 • 485 citations

New 4-Point Pharmacophore Method for Molecular Similarity and Diversity Applications: Overview of the Method and Applications, Including a Novel Approach to the Design of Combinatorial Libraries Containing Privileged Substructures

1999 • 377 citations

Drugs as P-glycoprotein substrates, inhibitors, and inducers

2002 • 364 citations

Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight

1998 • 336 citations

Genetic susceptibility to adverse drug reactions

2001 • 327 citations

How Does Consensus Scoring Work for Virtual Library Screening? An Idealized Computer Experiment

2001 • 300 citations

The Influence of Culture Time and Passage Number on the Morphological and Physiological Development of Caco-2 Cells

1997 • 295 citations

Progress in predicting human ADME parameters in silico

2000 • 266 citations

Evolutionary Optimization in Quantitative Structure−Activity Relationship: An Application of Genetic Neural Networks

1996 • 260 citations

Strategies for Absorption Screening in Drug Discovery and Development

2001 • 223 citations

Present and future in vitro approaches for drug metabolism

2000 • 222 citations

Evaluation of Dynamic Polar Molecular Surface Area as Predictor of Drug Absorption: Comparison with Other Computational and Experimental Predictors

1998 • 206 citations

Epithelial Transport of Drugs in Cell Culture. II: Effect of Extracellular Calcium Concentration on the Paracellular Transport of Drugs of Different Lipophilicities across Monolayers of Intestinal Epithelial (Caco-2) Cells

1990 • 183 citations

A Virtual Screening Approach Applied to the Search for Trypanothione Reductase Inhibitors

1997 • 142 citations

ConsDock: A new program for the consensus analysis of protein–ligand interactions

2002 • 115 citations

Development of predictive pharmacokinetic simulation models for drug discovery

2000 • 112 citations

Neighborhood Behavior of in Silico Structural Spaces with Respect to in Vitro Activity Spaces−A Novel Understanding of the Molecular Similarity Principle in the Context of Multiple Receptor Binding Profiles

2003 • 77 citations

Progress in computational methods for the prediction of ADMET properties.

2002 • 50 citations

Comparison of Knowledge-Based and Distance Geometry Approaches for Generation of Molecular Conformations

2001 • 50 citations

Neighborhood Behavior. Fuzzy Molecular Descriptors and their Influence on the Relationship between Structural Similarity and Property Similarity

2003 • 35 citations

Neighborhood Behavior of in Silico Structural Spaces with Respect to In Vitro Activity Spaces−A Benchmark for Neighborhood Behavior Assessment of Different in Silico Similarity Metrics

2003 • 33 citations

LIBRARY DESIGN AND VIRTUAL SCREENING USING MULTIPLE 4-POINT PHARMACOPHORE FINGERPRINTS

1999 • 31 citations

Design strategies for building drug-like chemical libraries.

2001 • 21 citations

The “Latent Membrane Permeability” Concept: QSPR Analysis of Inter/Intralaboratorically Variable Caco-2 Permeability

2002 • 17 citations

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