Multiple copies of a retroposon interrupt spliced leader RNA genes in the African trypanosome, Trypanosoma gambiense.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels

1977 • 1,607 citations

Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification

1970 • 1,556 citations

Evolution of Repeated DNA Sequences by Unequal Crossover

1976 • 1,208 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

A general model for genetic recombination.

1975 • 890 citations

The making of strand-specific M13 probes

1982 • 652 citations

Separation of Trypanosomes from the Blood of Infected Rats and Mice by Anion-exchangers

1968 • 433 citations

DISCONTINUOUS TRANSCRIPTION AND ANTIGENIC VARIATION IN TRYPANOSOMES

1986 • 418 citations

Antigenic variation in trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules

1984 • 368 citations

New Techniques for Purifying Large DNAs and Studying Their Properties and Packaging

1983 • 274 citations

Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3′ end

1981 • 258 citations

RNA-Mediated Gene Duplication: the Rat Preproinsulin I Gene Is a Functional Retroposon

1985 • 256 citations

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes

1984 • 193 citations

Ingi, a 5.2-kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian LINEs.

1987 • 182 citations

Identification of a small rna containing the trypanosome spliced leader: A donor of shared 5′ sequences of trypanosomatid mRNAs?

1984 • 176 citations

Calmodulin genes in trypanosomes are tandemly repeated and produce multiple mRNAs with a common 5' leader sequence.

1985 • 162 citations

Chromosome rearrangements in trypanosoma brucei

1984 • 161 citations

Tandem repetition of the 5′ mini-exon of variant surface glycoprotein genes: A multiple promoter for VSG gene transcription?

1983 • 152 citations

Discontinuous synthesis of mRNA in trypanosomes.

1984 • 145 citations

Trypanosoma brucei repeated element with unusual structural and transcriptional properties

1987 • 145 citations

Sequences homologous to the variant antigen mRNA spliced leader are located in tandem repeats and variable orphons in Trypanosoma brucei

1983 • 143 citations

Discontinuous transcription and splicing in trypanosomes

1986 • 93 citations

Complete nucleotide sequence of an unusual mobile element from trypanosoma brucei

1984 • 92 citations

Pulsed field gradient electrophoresis of DNA digested in agarose allows the sizing of the large duplication unit of a surface antigen gene in trypanosomes

1986 • 66 citations

Rearranged sequences of a human Kpn I element.

1984 • 64 citations

Ingi, a 5.2-kb Dispersed Sequence Element from Trypanosoma brucei That Carries Half of a Smaller Mobile Element at Either End and Has Homology with Mammalian LINEs

1987 • 55 citations

Variant surface glycoprotein gene expression site switches in Trypanosoma brucei.

1986 • 30 citations

Variant antigen genes of Trypanosoma brucei: genomic alteration of a spliced leader orphon and retention of expression-linked copies during differentiation.

1984 • 26 citations

Reverse transcription of trypanosome variable antigen mRNAs initiated by a specific oligonucleotide primer.

1983 • 25 citations

The trypanosome spliced leader small RNA gene family: stage-specific modification of one of several similar dispersed genes

1986 • 9 citations