Variant antigen genes of Trypanosoma brucei: genomic alteration of a spliced leader orphon and retention of expression-linked copies during differentiation.

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat ofTrypanosoma brucei

1975 • 917 citations

On the surface coat and flagellar adhesion in trypanosomes

1969 • 443 citations

Molecular basis for trypanosome antigenic variation

1982 • 369 citations

Growth of chromosome ends in multiplying trypanosomes

1983 • 244 citations

Transcripts coding for variant surface glycoproteins of Trypanosoma brucei have a short, identical exon at their 5′ end

1982 • 243 citations

Novel expression-linked copies of the genes for variant surface antigens in trypanosomes

1980 • 240 citations

Genomic environment of the expression-linked extra copies of genes for surface antigens of Trypanosoma brucei resembles the end of a chromosome

1982 • 183 citations

RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes

1982 • 183 citations

Cultivation ofTrypanosoma bruceisspp. in semi-defined and defined media

1973 • 176 citations

Characterization of the DNA duplication-transposition that controls the expression of two genes for variant surface glycoproteins in Trypanosoma brucei

1982 • 154 citations

Sequences homologous to the variant antigen mRNA spliced leader are located in tandem repeats and variable orphons in Trypanosoma brucei

1983 • 143 citations

Genomic environment of T. brucei VSG genes: presence of a minichromosome

1982 • 143 citations

The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei

1983 • 138 citations

Gene duplication and transposition linked to antigenic variation in Trypanosoma brucei.

1981 • 127 citations

Changes in oxidative metabolism and ultrastructure accompanying differentiation of the mitochondrion in Trypanosoma brucei

1973 • 116 citations

The expression-linked copy of surface antigen gene in Trypanosoma is probably the one transcribed

1981 • 105 citations

Analysis of genomic rearrangements associated with two variable antigen genes of Trypanosoma brucei

1982 • 85 citations

Trypanosoma brucei: Morphometric changes and loss of infectivity during transformation of bloodstream forms to procyclic culture forms in vitro

1979 • 61 citations

Molecular characterization of initial variants from the IsTat I serodeme of Trypanosoma brucei

1983 • 57 citations

Trypanosoma rhodesiense blood forms express all antigen specificities relevant to protection against metacyclic (insect form) challenge.

1982 • 50 citations

Trypanosoma brucei: Loss of variable antigens during transformation from bloodstream to procyclic forms in vitro

1979 • 46 citations

Mitochondrial and cytoplasmic ribosomes and their activity in blood and culture form Trypanosoma brucei.

1975 • 37 citations

Genomic organization of Trypanosoma brucei variant antigen gene families in sequential parasitemias

1983 • 35 citations

In vitro cultivation of pleomorphic Trypanosoma brucei stocks: a possible source of variable antigens for immunization studies

1981 • 12 citations