A Role for the Molecular Chaperone Protein BiP/GRP78 in Drosophila Sleep Homeostasis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Direct Approach to False Discovery Rates

2002 • 5,455 citations

THE MAMMALIAN UNFOLDED PROTEIN RESPONSE

2005 • 2,964 citations

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

2000 • 2,696 citations

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1988 • 1,292 citations

Transcriptional and Translational Control in the Mammalian Unfolded Protein Response

2002 • 909 citations

Complementary Signaling Pathways Regulate the Unfolded Protein Response and Are Required for C. elegans Development

2001 • 693 citations

Extensive and Divergent Effects of Sleep and Wakefulness on Brain Gene Expression

2004 • 611 citations

Stress response genes protect against lethal effects of sleep deprivation in Drosophila

2002 • 465 citations

The Unfolding Tale of the Unfolded Protein Response

2001 • 398 citations

Overexpression of GRP78 mitigates stress induction of glucose regulated proteins and blocks secretion of selective proteins in Chinese hamster ovary cells.

1992 • 348 citations

Immunoglobulin Binding Protein (BiP) Function Is Required to Protect Cells from Endoplasmic Reticulum Stress but Is Not Required for the Secretion of Selective Proteins

1997 • 346 citations

The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum.

1993 • 246 citations

Sleep deprivation induces the unfolded protein response in mouse cerebral cortex

2005 • 200 citations

Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep

2003 • 147 citations

Orchestrating the unfolded protein response in health and disease

2002 • 131 citations