Chromosome Aberration Formation and Sister Chromatid Exchange in Relation to DNA Repair in Human Cells

New Giemsa method for the differential staining of sister chromatids

1974 • 3,198 citations

Defective Repair Replication of DNA in Xeroderma Pigmentosum

1968 • 1,739 citations

A mechanism for gene conversion in fungi

1964 • 1,459 citations

Cytological detection of mutagen–carcinogen exposure by sister chromatid exchange

1975 • 1,333 citations

A mechanism for gene conversion in fungi

2007 • 1,149 citations

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

1968 • 1,089 citations

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

1975 • 984 citations

A Manyfold Increase in Sister Chromatid Exchanges in Bloom's Syndrome Lymphocytes

1974 • 934 citations

A general model for genetic recombination.

1975 • 890 citations

Microfluorometric Detection of Deoxyribonucleic Acid Replication in Human Metaphase Chromosomes

1973 • 838 citations

THE ORGANIZATION AND DUPLICATION OF CHROMOSOMES AS REVEALED BY AUTORADIOGRAPHIC STUDIES USING TRITIUM-LABELED THYMIDINEE

1957 • 824 citations

Birth Defects Original Article Series

1970 • 783 citations

Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.

1975 • 617 citations

Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli

1971 • 582 citations

Progress in Genetic Toxicology

1978 • 581 citations

A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.

1973 • 533 citations

Sister chromatid exchange as an indicator of mutagenesis

1978 • 504 citations

Sister Chromatid Exchanges, Indices of Human Chromosome Damage and Repair: Detection by Fluorescence and Induction by Mitomycin C

1974 • 491 citations

A model for replication repair in mammalian cells

1976 • 443 citations

Postreplication repair of DNA in ultraviolet-irradiated mammalian cells

1972 • 439 citations

Chromosomes and Cancer.

1975 • 437 citations

Bloom’s Syndrome

1995 • 422 citations

XERODERMA PIGMENTOSUM: A HUMAN DISEASE IN WHICH AN INITIAL STAGE OF DNA REPAIR IS DEFECTIVE

1969 • 417 citations

Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts

1976 • 365 citations

Mechanisms of chromosomal aberration production III. Chemicals and ionizing radiation

1974 • 363 citations

Repair Replication of Mammalian Cell DNA: Effects of Compounds That Inhibit DNA Synthesis or Dark Repair

1969 • 355 citations

Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells

1976 • 331 citations

Sister chromatid exchanges induced in chinese hamster cells by UV irradiation of different stages of the cell cycle: The necessity for cells to pass through S

1974 • 312 citations

Spontane Chromosomenaberrationen bei famili�rer Panmyelopathie

1964 • 311 citations

Spontaneous sister chromatid exchanges detected by a BUdR-labelling method

1974 • 309 citations

Chromosomal Breakage in a Rare and Probably Genetically Determined Syndrome of Man

1965 • 307 citations

Evidence for Excision of Ultraviolet-Induced Pyrimidine Dimers from the DNA of Human Cells In Vitro

1968 • 304 citations

Cross-link repair in human cells and its possible defect in Fanconi's anemia cells

1977 • 294 citations

Caffeine and chromosomes

1977 • 276 citations

Chromosome-sized DNA molecules from Drosophila

1973 • 267 citations

Chromosomes and cancer

2009 • 266 citations

Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia.

1975 • 266 citations

Xeroderma Pigmentosum: Variants with Normal Dna Repair and Normal Sensitivity to Ultraviolet Light

1972 • 244 citations

Chromatid structure: relationship between DNA content and nucleotide sequence diversity

1971 • 241 citations

Sister chromatid exchanges induced by mutagenic carcinogens in normal and xeroderma pigmentosum cells

1977 • 238 citations

A Theory of Crossing-Over by Means of Hybrid Deoxyribonucleic Acid

1963 • 238 citations

Genetic recombination: The nature of a crossed strand-exchange between two homologous DNA molecules

1972 • 237 citations

Single strand interruptions in DNA and the effects of caffeine in Chinese hamster cells irradiated with ultraviolet light

1969 • 221 citations

Spontaneous and Induced Sister Chromatid Exchanges as Revealed by the BUdR-Labeling Method

1977 • 220 citations

Is Fanconi's anaemia defective in a process essential to the repair of DNA cross links?

1975 • 216 citations

Sister chromatid exchange as an assay for genetic damage induced by mutagen-carcinogens. II. In vitro test for compounds requiring metabolic activation

1976 • 216 citations

A retarded rate of DNA chain growth in Bloom's syndrome.

1975 • 210 citations

Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested from cytogenetic observations

1978 • 209 citations

Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis.

1978 • 206 citations

Mutagen-induced Chromosome Damage in Man

1979 • 205 citations

Sister chromatid exchanges—A sensitive assay of agents damaging human chromosomes

1975 • 204 citations

Induction of sister chromatid exchanges by chemical mutagens and its possible relevance to DNA repair

1974 • 197 citations

Is chromatid-type damage in ataxia telangiectasia after irradiation at G0 a consequence of defective repair?

1976 • 197 citations

Cytological Evidence for Crossing-Over in vitro in Human Lymphoid Cells

1964 • 196 citations

THE mei-9a MUTANT OF DROSOPHILA MELANOGASTER INCREASES MUTAGEN SENSITIVITY AND DECREASES EXCISION REPAIR

1976 • 186 citations

Induction of sister chromatid exchanges by UV light and its inhibition by caffeine

1973 • 180 citations

Sister chromatid exchange in human chromosomes from normal individuals and patients with ataxia telangiectasia

1975 • 179 citations

DNA single-strand breaks during repair of UV damage in human fibroblasts and abnormalities of repair in xeroderma pigmentosum.

1976 • 176 citations

DNA repair and its coupling to DNA replication in eukaryotic cells

1978 • 175 citations

CHROMOSOME EXCHANGES IN HUMAN LEUKOCYTES INDUCED BY MITOMYCIN C

1965 • 167 citations

Caffeine and chromosomes

1978 • 165 citations

Ultraviolet light sensitivity and delayed DNA-chain maturation in Bloom's syndrome fibroblasts

1977 • 162 citations

A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture

1977 • 161 citations

CHARACTERIZATION OF POSTREPLICATION REPAIR IN MUTAGEN-SENSITIVE STRAINS OF DROSOPHILA MELANOGASTER

1976 • 159 citations

In vitro chromosomal radiosensitivity in “chromosomal breakage syndromes”

1973 • 149 citations

Unusual sensitivity of ataxia telangiectasia cells to bleomycin.

1979 • 148 citations

Advances in cell and molecular biology

1973 • 148 citations

Bloom's syndrome. III. Analysis of the chromosome aberration characteristic of this disorder

1974 • 146 citations

Replicative bypass repair of ultraviolet damage to DNA of mammalian cells: Caffeine sensitive and caffeine resistant mechanisms

1976 • 143 citations

Effects of caffeine and theophylline on dna synthesis in unirradiated and UV-irradiated mammalian cells

1974 • 142 citations

Mechanisms for sister chromatid exchanges and their relation to the production of chromosomal aberrations

1977 • 141 citations

The influence of caffeine on cell survival in excision-proficient and excision-deficient xeroderma pigmentosum and normal human cell strains following ultraviolet-light irradiation

1975 • 140 citations

On the mechanism of genetic recombination: electron microscopic observation of recombination intermediates.

1976 • 135 citations

Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

1978 • 126 citations

THE FREQUENCY OF SISTER CHROMATID EXCHANGES FOLLOWING EXPOSURE TO VARYING DOSES OF H3-THYMIDINE OR X-RAYS

1964 • 116 citations

Induction of sister chromatid exchanges in xeroderma pigmentosum cells after exposure to ultraviolet light

1977 • 116 citations

Postreplication repair of DNA in mammalian cells

1974 • 114 citations

DNA repair with purines and pyrimidines in radiation- and carcinogen-damaged normal and xeroderma pigmentosum human cells.

1973 • 111 citations

Inhibition of post-replication repair of alkylated DNA by caffeine in Chinese hamster cells but not HeLa cells

1973 • 110 citations

Repair of DNA damaged by alkylating carcinogens is defective in xeroderma pigmentosum-derived fibroblasts

1977 • 109 citations

Mechanisms of chromosomal aberration production I. Aberration induction by ultraviolet light

1973 • 105 citations

Effect of tumor promoters, protease inhibitors, and repair processes on x-ray-induced sister chromatid exchanges in mouse cells.

1979 • 104 citations

Inhibition of repair of UV-damaged DNA by caffeine and mutation induction in Chinese hamster cells

1973 • 98 citations

DNA replication in mammalian cells in the presence of cycloheximide

1973 • 97 citations

Caffeine-sensitive repair of ultraviolet light-damaged DNA of mouse L cells

1972 • 97 citations

Effect of phorbol myristate acetate on the recovery of spontaneous and ultraviolet light-induced 6-thioguanine and ouabain-resistant Chinese hamster cells.

1977 • 97 citations

Possible role of DNA synthesis in formation of sister chromatid exchanges

1974 • 97 citations

Steps in DNA Chain Elongation and Joining after Ultra-violet Irradiation of Human Cells

1972 • 96 citations

Spermine and spermidine-induced B̄ to Ā transition of DNA in solution

1979 • 95 citations

Sister chromatid exchanges induced by mitomycin C: a new method of detecting DNA damage at chromosomal level

1975 • 93 citations

Repair of alkylation damage in ultraviolet-sensitive (xeroderma pigmentosum) human cells

1971 • 92 citations

SISTER CHROMATID EXCHANGE IN XERODERMA PIGMENTOSUM CELLS THAT ARE DEFECTIVE IN DNA EXCISION REPAIR OR POST-REPLICATION REPAIR

1975 • 88 citations

Genetic control of chromosome breakage and rejoining in Drosophila melanogaster: spontaneous chromosome aberrations in X-linked mutants defective in DNA metabolism.

1979 • 86 citations

Chromatid exchanges in ataxia telangiectasia, Bloom syndrome, Werner syndrome, and xeroderrna pigmentosum

1976 • 83 citations

DNA repair capacity and susceptibility to chromosome breakage in xeroderma pigmentosum cells

1973 • 80 citations

Characterization of sister chromatid exchange induction by 8-methoxypsoralen plus near UV light

1978 • 80 citations

Altered rate of DNA replication in ageing human fibroblast cultures

1974 • 80 citations

Reduced DNA repair synthesis in xeroderma pigmentosum cells exposed to the oncogenic 4-nitroquinoline 1-oxide and 4-hydroxy-aminoquinoline 1-oxide

1971 • 79 citations

Repair of mitomycin C damage to DNA in mammalian cells and its impairment in Fanconi's anemia cells

1975 • 72 citations

Frequency and distribution of sister-chromatid exchanges in a case of Fanconi's anemia

1975 • 70 citations

FANCONI'S ANEMIA A CONDITION POSSIBLY ASSOCIATED WITH A DEFECTIVE DNA REPAIR

1978 • 70 citations

Molecular human cytogenetics

1977 • 69 citations

Caffeine inhibition of postreplication repair of N-acetoxy-2-acetylamino fluorene-damaged DNA in Chinese hamster cells.

1973 • 68 citations

RELATION BETWEEN DNA REPAIR, CHROMOSOME ABERRATIONS, AND SISTER CHROMATID EXCHANGES

1978 • 67 citations

Sister chromatid exchange and chromatid interchange as possible manifestation of different DNA repair processes

1977 • 67 citations

The induction of chromatid deletions in accord with the breakage-and-reunion hypothesis

1975 • 65 citations

Sister chromatid exchanges in ageing and repair-deficient human fibroblasts

1976 • 64 citations

Recombination promoted by superhelical DNA and the recA gene of Escherichia coli.

1976 • 64 citations

A gross reduction in chiasma formation during meiotic prophase and a defective DNA repair mechanism associated with a case of human male infertility

1970 • 60 citations

Effect of tumor promoting agents on mutation frequencies in cultured V79 Chinese hamster cells

1977 • 58 citations

Mutagen-induced Chromosome Damage in Man

1979 • 57 citations

Ataxia telangiectasia: The effects of chemical mutagens and x-rays on sister chromatid exchanges in blood lymphocytes

1977 • 57 citations

DNA repair enzymes in ataxia telangiectasia and Bloom's syndrome fibroblasts

1977 • 57 citations

Induction of sister chromatid exchanges by transformation with simian virus 40.

1978 • 56 citations

Characteristics of DNA synthesis following ultraviolet light irradiation in mouse L cells

1972 • 56 citations

Mechanisms of chromosomal aberration production II. Aberrations induced by 5-bromodeoxyuridine and visible light

1973 • 55 citations

Chromosome breakage and blastic transformation of lymphocytes in ataxia-telangiectasia

1967 • 54 citations

Aging and sister chromatid exchange

1978 • 54 citations

Advances in cell and molecular biology

1971 • 53 citations

Effects of caffeine on the frequencies of chromosomal aberrations and sister chromatid exchanges induced by chemical mutagens in root tips of Vicia faba

2009 • 53 citations

Ultraviolet light-induced sister chromatid exchanges in xeroderma pigmentosum and in Cockayne's syndrome lymphocyte cell lines.

1978 • 48 citations

Parallel distribution of sister chromatid exchanges and chromosome aberrations

1976 • 47 citations

Studies on a recombination-deficient mutant of drosophila II. Response to X-rays and alkylating agents

1972 • 41 citations

Effect of caffeine on sister chromatid exchanges and chromosomal aberrations induced by mutagens in Chinese hamster cells

1977 • 40 citations

The effect of aging on sister chromatid exchange

1979 • 38 citations

ATAXIA TELANGIECTASIA: A MODEL INHERITED DISEASE LINKING DEFICIENT DNA REPAIR WITH RADIOSENSITIVITY AND CANCER PRONENESS

1978 • 38 citations

Xeroderma Pigmentosum Epidermal Cells with Normal UV-Induced Thymidine Incorporation

1972 • 37 citations

Caffeine inhibition of prereplication repair of mitomycin C-induced DNA damage in human peripheral lymphocytes

1978 • 37 citations

Studies on a recombination-deficient mutant of drosophila

1969 • 36 citations

The effect of methylated oxypurines on the size of newly-synthesized DNA and on the production of chromosome aberrations after UV irradiation in chinese hamster cells

1975 • 36 citations

The differential sensitivity of desynaptic and normal genotypes of barley to X-rays

1966 • 33 citations

Role of sister chromatid exchanges in chromatid aberration formation

1977 • 32 citations

Effect of cycloheximide on regulatory protein for initiating mammalian DNA replication at the nuclear membrane.

1972 • 31 citations

UV-light induced sister chromatid exchanges in xeroderma pigmentosum lymphocytes

1977 • 29 citations

The relevance of caffeine post-treatment to SCE incidence induced in Chinese hamster cells

1979 • 27 citations

The frequency and distribution of isolabelling in Chinese hamster chromosomes after exposure to X-rays

1974 • 25 citations

Polyamine deficiency reduces the rate of DNA replication fork movement in Escherichia coli

1978 • 24 citations

Effects of caffeine on sister chromatid exchange (SCE) after exposure to UV light or triaziquone studied with a fluorescence plus Giemsa (FPG) technique

1978 • 24 citations

Intermediate fragments of newly replicated DNA in mammalian cells. II. Effect of cycloheximide on DNA chain elongation

1971 • 21 citations

Variation with Sex of Irradiation-induced Chromosome Damage in Somatic Cells of Drosophila melanogaster

1974 • 17 citations

Sister chromatid exchanges and chromatid interchanges in Bloom's syndrome

1975 • 16 citations

Parallel induction of sister chromatid exchanges and infectious virus from SV40-transformed cells by alkylating agents

1978 • 15 citations

Abnormal DNA repair of 4-nitroquinoline-1-oxide-induced damage by lymphocytes in Xeroderma pigmentosum

1972 • 14 citations

Repair replication and sister chromatid exchanges as indicators of excisable and nonexcisable damage in human (xeroderma pigmentosum) cells

1977 • 14 citations

The influence of caffeine on the mitomycin C-induced chromosome aberration frequency in normal human and xeroderma pigmentosum cells

1978 • 12 citations

Cassures chromosomiques dans l'incontinentia pigmenti. Etude d'une famille.

1972 • 8 citations

Lithium and nuclear fusion

1976 • 4 citations