Inhibition of repair of UV-damaged DNA by caffeine and mutation induction in Chinese hamster cells

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

1968 • 1,089 citations

FRACTIONATION AND CHARACTERIZATION OF A CYCLIC ADENINE RIBONUCLEOTIDE FORMED BY TISSUE PARTICLES

1958 • 1,055 citations

Tables for determining the statistical significance of mutation frequencies

1970 • 966 citations

Reconstruction in vivo of Irradiated Escherichia coli Deoxyribonucleic Acid; the Rejoining of Broken Pieces

1966 • 727 citations

Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli

1971 • 582 citations

Thermal Conversion of Nonpriming Deoxyribonucleic Acid to Primer

1959 • 545 citations

Postreplication repair of DNA in ultraviolet-irradiated mammalian cells

1972 • 439 citations

Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.

1968 • 376 citations

Repair Replication of Mammalian Cell DNA: Effects of Compounds That Inhibit DNA Synthesis or Dark Repair

1969 • 355 citations

Evidence for Excision of Ultraviolet-Induced Pyrimidine Dimers from the DNA of Human Cells In Vitro

1968 • 304 citations

The Mechanism of the Action of Caffeine on Sarcoplasmic Reticulum

1968 • 298 citations

ULTRAVIOLET-INDUCED MUTATION AND DNA REPAIR

1969 • 252 citations

Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents

1969 • 245 citations

Single strand interruptions in DNA and the effects of caffeine in Chinese hamster cells irradiated with ultraviolet light

1969 • 221 citations

Evidence for Dark-Reactivation of Ultraviolet Light Damage in Mouse L Cells

1967 • 216 citations

The Induction of Thymine Dimers in Ultraviolet-Irradiated Mammalian Cells

1965 • 168 citations

Physical changes and mutagenesis

1964 • 157 citations

MAMMALIAN CELL GENETICS I. SELECTION AND CHARACTERIZATION OF MUTATIONS AUXOTROPHIC FOR L-GLUTAMINE OR RESISTANT TO 8-AZAGUANINE IN CHINESE HAMSTER CELLS IN VITRO

1969 • 145 citations

[13] The excision of pyrimidine dimers (The detection of dimers in small amounts)

1971 • 134 citations

Time and Dose Relationships in Radiation Biology as Applied to Radiotherapy

1971 • 133 citations

The mutagenic action of caffeine in higher organisms.

1968 • 121 citations

The Interaction of Caffeine with Ultra-violet-light-irradiated DNA

1970 • 113 citations

DNA Replication and Recombination after UV Irradiation

1968 • 112 citations

THYMINE DIMERIZATION IN L‐STRAIN MAMMALIAN CELLS AFTER IRRADIATION WITH ULTRAVIOLET LIGHT AND THE SEARCH FOR REPAIR MECHANISMS

1966 • 108 citations

Mechanism of Caffeine Enhancement of Mutations Induced by Sublethal Ultraviolet Dosages

1968 • 106 citations

Effects of Caffeine on Ultraviolet-Irradiated Mouse L Cells

1969 • 101 citations

Caffeine potentiation of the lethal action of alkylating agents on L-cells

1971 • 98 citations

Caffeine-sensitive repair of ultraviolet light-damaged DNA of mouse L cells

1972 • 97 citations

Steps in DNA Chain Elongation and Joining after Ultra-violet Irradiation of Human Cells

1972 • 96 citations

Differential effects of acriflavine and caffeine on various ultraviolet-irradiated Escherichia coli strains and T1 phage

1967 • 95 citations

The mutagenic activity of caffeine in man

1965 • 95 citations

Inhibition of host cell reactivation in phage T1 by caffeine

1964 • 90 citations

DNA Chain Elongation and Joining in Normal Human and Xeroderma Pigmentosum Cells after Ultraviolet Irradiation

1972 • 90 citations

Effects of caffeine on L-cells exposed to mitomycin C.

1970 • 88 citations

Enhancement of ultraviolet-induced mutation in bacteria by caffeine

1961 • 87 citations

The role of metabolic cooperation in selection of hypoxanthine-guanine-phosphoribosyl-transferase (HG-PRT)-deficient mutants from diploid mammalian cell strains

1972 • 82 citations

Xeroderma Pigmentosum: A Rapid Sensitive Method for Prenatal Diagnosis

1971 • 79 citations

Ultraviolet-Light Irradiation of Mouse L Cells: Effects on Cells in the DNA Synthesis Phase

1969 • 75 citations

STUDY OF PYRIMIDINE DIMERS IN MAMMALIAN CELLS SURVIVING LOW DOSES OF ULTRAVIOLET RADIATION*

1967 • 71 citations

Mechanisms of Radiation Mutagenesis in Cellular and Subcellular Systems

1969 • 71 citations

Response of a "Resistant" Plasmacytoma to Alkylating Agents and X-Ray in Combination with the "Excision Repair Inhibitors Caffeine and Chloroquine

1969 • 67 citations

Evidence for linkage of 3-phosphoglycerate kinase, hypoxanthine-guanine-phosphoribosyl transferase, and glucose 6-phosphate dehydrogenase loci in Chinese hamster cells studied by using a relationship between gene multiplicity and enzyme activity

1972 • 63 citations

Chemical mutagenesis in mammals and man

1971 • 59 citations

Mutagenicity tests in mice

1968 • 57 citations

Effects of caffeine on the induction of mutations in Chinese hamster cells by ultraviolet light

1971 • 57 citations

The effect of caffeine on the repair of ultraviolet-damaged DNA in bacteria

1967 • 56 citations

Dark Reactivation of Damage induced by Ultraviolet Light in Mammalian Cells in vitro

1968 • 55 citations

The induction of 8-azaguanine-resistant mutants in cultured Chinese hamster cells by ultraviolet light the effect of chenges in post-irradiation conditions

1972 • 55 citations

Excision of Pyrimidine Dimers from Ultraviolet‐Irradiated DNA by Exonucleases from Mammalian Cells

1971 • 52 citations

Effects of post-treatment with caffeine on the sensitivity to ultraviolet light irradiation of two lines of HeLa cells

1970 • 52 citations

Induction of Thymine Dimers in Synchronized Populations of Chinese Hamster Cells

1966 • 51 citations

: Caffeine, caffeine derivatives and chromosomal aberrations IV. Synergism between Mitomycin Cand caffeine in Chinese hamster cells

2009 • 51 citations

The failure of caffeine to induce mutagenic effects or to synergize the effects of known mutagens in mice

1970 • 50 citations

Nascent DNA synthesis in ultraviolet light-irradiated mouse L cells

1972 • 49 citations

“MUTATIONAL SYNERGISM” OF ULTRAVIOLET LIGHT AND CAFFEINE IN ESCHERICHIA COLI

1962 • 48 citations

On the effect of caffeine on mutation and recombination in Schizosaccharomyces pombe

1971 • 45 citations

A CONVENIENT METHOD FOR ASSAY OF DNA SYNTHESIS IN SYNCHRONIZED HUMAN CELL CULTURES

1966 • 39 citations

Caffeine, caffeine derivatives and chromosomal aberrations

2009 • 37 citations

DNA-degradation Products from Mammalian Cells Irradiated with Ultra-violet Light

1969 • 31 citations

Inhibition of dark repair of ultraviolet damage in DNA by caffeine and 8-chlorocaffeine. Kinetics of inhibition

1968 • 26 citations

A Failure of Specific Inhibitors to Affect Survival of Chinese Hamster Cells Exposed to Ultra-violet Light

1968 • 23 citations

The enhancement of the mutagenic effect of ultraviolet radiation inEscherichia coli by caffeine and acriflavine

1968 • 22 citations

A RAPID METHOD FOR THE ISOLATION AND COLLECTION OF NUCLEI FROM WHOLE CELL SUSPENSIONS

1964 • 19 citations

Caffeine, caffeine derivatives and chromosomal aberrations

2009 • 18 citations

Effect of caffeine on the induction of mutations in Chinese hamster cells by ultraviolet light

1972 • 12 citations

Mutation as Cellular Process

1971 • 12 citations

The role of pyrimidine dimers in the inhibition of DNA synthesis in mammalian cells after ultraviolet irradiation: the mathematical interpretation of results

1970 • 11 citations

Effects of caffeine on the induction of mutations in Chinese hamster cells by ultraviolet light

1971 • 1 citations