Introduction and General Overview

DNA Methylation and Gene Function

1980 • 2,069 citations

DNA Modification Mechanisms and Gene Activity During Development

1975 • 1,859 citations

X inactivation, differentiation, and DNA methylation

1975 • 1,283 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine

1979 • 1,101 citations

5-Methylcytosine in Eukaryotic DNA

1981 • 744 citations

THE QUANTITATIVE SEPARATION OF PURINES, PYRIMIDINES, AND NUCLEOSIDES BY PAPER CHROMATOGRAPHY

1948 • 707 citations

DNA Modification and Restriction

1969 • 624 citations

DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells

1981 • 464 citations

Substrate and sequence specificity of a eukaryotic DNA methylase

1982 • 441 citations

5-Methylcytosine, Gene Regulation, and Cancer

1983 • 425 citations

The modified nucleosides in nucleic acids

1971 • 392 citations

Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA.

1983 • 361 citations

Use of restriction enzymes to study eukaryotic DNA methylation

1978 • 281 citations

Recognition and estimation of 5-methylcytosine in nucleic acids

1951 • 236 citations

The absence of detectable methylated bases in Drosophila melanogaster DNA

1982 • 211 citations

Induction of thymidine kinase in enzyme-deficient chinese hamster cells

1982 • 205 citations

The occurrence of 6-methylaminopurine in deoxyribonucleic acids

1958 • 205 citations

Dna Methylation and its Possible Biological Roles

1981 • 202 citations

Eukaryotic DNA methylation

1983 • 192 citations

DNA Methylation--A Regulatory Signal in Eukaryotic Gene Expression

1981 • 192 citations

Enzymatic Alteration of Nucleic Acid Structure

1964 • 161 citations

Methylation of Mouse Liver DNA Studied by Means of the Restriction Enzymes Msp I and Hpa II

1979 • 146 citations

The tumorigenicity of 5-azacytidine in the male Fischer rat

1984 • 143 citations

Active gene sequences are undermethylated.

1981 • 139 citations

THE ACTION OF PANCREATIC DEOXYRIBONUCLEASE

1955 • 129 citations

Possible epigenetic mechanisms of tumor progression: Induction of high-frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties of tumor cell populations by 5-azacytidine treatment

1984 • 125 citations

Induction of the metastatic phenotype in a mouse tumor model by 5-azacytidine, and characterization of an antigen associated with metastatic activity.

1984 • 110 citations

Mutagenicity of 5-azacytidine and related nucleosides in C3H/10T 1/2 clone 8 and V79 cells.

1982 • 98 citations

THE ENZYMATIC METHYLATION OF RNA AND DNA, II. ON THE SPECIES SPECIFICITY OF THE METHYLATION ENZYMES

1963 • 93 citations

Deoxyribonucleic acid methylase of mammalian tissues

1968 • 85 citations

DNA Methylation in Eukaryotic Cells

1984 • 81 citations

The level of expression of the rat growth hormone gene in liver tumor cells is at least eight orders of magnitude less than that in anterior pituitary cells.

1983 • 62 citations

Deoxyribonucleic Acid Methylase Activity in Rat Spleen

1968 • 38 citations

Eukaryotic DNA methylation

1980 • 38 citations

Enzymatic dna methylation in higher eukaryotes

1980 • 36 citations

The control of gene function in cell differentiation and in embryogenesis.

1971 • 31 citations

25 DNA Methylation

1981 • 30 citations