Granulosa Cells as Hormone Targets: The Role of Biologically Active Follicle-Stimulating Hormone in Reproduction

Glycoprotein Hormones: Structure and Function

1981 • 2,296 citations

There is more than one interleukin 1

1986 • 1,226 citations

Transforming Growth Factor-β: Biological Function and Chemical Structure

1986 • 1,198 citations

Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

1986 • 1,148 citations

Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin

1986 • 1,071 citations

Hormonal Regulation of the Differentiation of Cultured Ovarian Granulosa Cells*

1984 • 1,015 citations

Insulin-Like Growth Factors as Intraovarian Regulators of Granulosa Cell Growth and Function*

1985 • 921 citations

Insulin-like growth factor II receptor as a multifunctional binding protein

1987 • 858 citations

Loss of Circadian Rhythmicity in Blood Testosterone Levels with Aging in Normal Men*

1983 • 770 citations

Changes with Age in Levels of Serum Gonadotropins, Prolactin, and Gonadal Steroids in Prepubertal Male and Female Rats

1975 • 730 citations

Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

1985 • 722 citations

ASSAY OF THE FOLLICLE STIMULATING HORMONE BASED ON THE AUGMENTATION WITH HUMAN CHORIONIC GONADOTROPIN

1953 • 696 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues

1985 • 568 citations

Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions.

1988 • 553 citations

Radioimmunoassay for Human Follicle-Stimulating Hormone¹

1967 • 540 citations

Studies on the role of plasminogen activator in ovulation. In vitro response of granulosa cells to gonadotropins, cyclic nucleotides, and prostaglandins.

1976 • 502 citations

Isolation of inhibin from bovine follicular fluid

1985 • 499 citations

The Physiology of Gonadotropin-Releasing Hormone (GnRH) Secretion in Men and Women

1985 • 489 citations

The Gonadotropic Function of Insulin*

1987 • 454 citations

Dual Endocrine Activity of the Testes

1932 • 451 citations

Extrapituitary Actions of Gonadotropin-Releasing Hormone*

1981 • 445 citations

Ovarian plasminogen activator: Relationship to ovulation and hormonal regulation

1975 • 440 citations

Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid.

1985 • 434 citations

Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis.

1987 • 422 citations

Tissue Distribution of Insulin-Like Growth Factor I and II Messenger Ribonucleic Acid in the Adult Rat*

1987 • 418 citations

Purification and characterization of Erythroid Differentiation Factor(EDF) isolated from human leukemia cell line THP-1

1987 • 409 citations

Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation

1977 • 389 citations

Cloning and sequence analysis of a cDNA for rat transforming growth factor-α

1985 • 388 citations

Pituitary and Gonadal Hormones in Women during Spontaneous and Induced Ovulatory Cycles

1970 • 376 citations

Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells

1976 • 374 citations

COMPARISON OF WEIGHT REDUCTION WITH METOPROLOL IN TREATMENT OF HYPERTENSION IN YOUNG OVERWEIGHT PATIENTS

1985 • 370 citations

Tumor growth inhibition in patients with prostatic carcinoma treated with luteinizing hormone-releasing hormone agonists.

1982 • 364 citations

Molecular Characterization of Fibroblast Growth Factor: Distribution and Biological Activities in Various Tissues

1986 • 340 citations

Protein Hormone Action: A Key to Understanding Ovarian Follicular and Luteal Cell Development

1976 • 337 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

Isolation of porcine follicular fluid inhibin of 32K daltons

1985 • 327 citations

Reproductive Functions in Young Fathers and Grandfathers

1982 • 323 citations

Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization, and some biological properties of forms I and II.

1976 • 319 citations

Structure of two human ovarian inhibins

1986 • 307 citations

Reversible Inhibition of Testicular Steroidogenesis and Spermatogenesis by a Potent Gonadotropin-Releasing Hormone Agonist in Normal Men

1981 • 294 citations

Purification and partial characterization of inhibin from porcine follicular fluid

1985 • 292 citations

Recent Advances in the Endocrinology of Puberty

1980 • 288 citations

Further Studies on Leydig Cell Function in Old Age

1974 • 275 citations

Importance of FSH-releasing protein and inhibin in erythrodifferentiation

1987 • 275 citations

Cloning and sequence analysis of cDNA species coding for the two subunits of inhibin from bovine follicular fluid.

1986 • 273 citations

The cDNA for the β-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3′-untranslated region

1980 • 271 citations

Declining testicular function with age

1974 • 266 citations

Corpus Luteum Angiogenic Factor Is Related to Fibroblast Growth Factor*

1985 • 260 citations

Localization, Secretion, and Action of Inhibin in Human Placenta

1987 • 258 citations

Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells.

1986 • 254 citations

Biosynthesis and Secretion of Follicle-Stimulating Hormone*

1983 • 254 citations

Gonadotropins and Estradiol Stimulate Immunoreactive Insulin-Like Growth Factor-I Production by Porcine Granulosa Cells in Vitro*

1987 • 248 citations

Molecular Aspects of Hormone Action in Ovarian Follicular Development, Ovulation, and Luteinization

1988 • 244 citations

Dynamic Changes in Inhibin Messenger RNAs in Rat Ovarian Follicles During the Reproductive Cycle

1988 • 242 citations

REGULATION OF THE TESTIS SERTOLI CELL BY FOLLICLE STIMULATING HORMONE

1980 • 236 citations

GROWTH HORMONE INCREASES OVARIAN LEVELS OF IMMONOREACTIVE SOMATOMEDIN C/INSULIN-LIKE GROWTH FACTOR IIN VIVO.

1986 • 234 citations

Complementary Deoxyribonucleic Acid (cDNA) Cloning and DNA Sequence Analysis of Rat Ovarian Inhibins*

1987 • 228 citations

Hormonal, Histological and Chromosomal Studies in Adult Males with Testicular Disorders¹

1972 • 227 citations

PRODUCTION OF INSULIN-LIKE GROWTH FACTORS BY OVARIAN GRANULOSA CELLS

1985 • 213 citations

Inhibin-Mediated Feedback Control of Follicle-Stimulating Hormone Secretion in the Female Rat

1986 • 212 citations

Rat Inhibin: Molecular Cloning of α- and β-Subunit Complementary Deoxyribonucleic Acids and Expression in the Ovary

1987 • 209 citations

Prorenin in High Concentrations in Human Ovarian Follicular Fluid

1986 • 209 citations

Hormonal Regulation of Granulosa Cell Inhibin Biosynthesis*

1986 • 208 citations

Growth Factors Modulate Gonadotropin Receptor Induction in Granulosa Cell Cultures

1981 • 207 citations

Inhibin and beta type transforming growth factor (TGFβ) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells

1986 • 206 citations

Effects of bovine inhibin, transforming growth factor-β and bovine activin-A on granulosa cell differentiation

1987 • 205 citations

A single gonadotropin alpha-subunit gene in normal tissue and tumor-derived cell lines.

1981 • 204 citations

Rapid Changes in the Expression of Inhibin α-, βA-, and βB-Subunits in Ovarian Cell Types During the Rat Estrous Cycle

1988 • 203 citations

Ovarian Thecal Cells Produce Transforming Growth Factor-β Which Can Regulate Granulosa Cell Growth*

1987 • 201 citations

Relationship between Spermatogenesis and Serum Gonadotropin Levels in Azoospermia and Oligospermia

1972 • 200 citations

Inhibin A-subunit cDNAs from porcine ovary and human placenta.

1986 • 197 citations

Expression of Biologically Active Human Follitropin in Chinese Hamster Ovary Cells

1989 • 196 citations

Vasoactive Intestinal Polypeptide Occurs in Nerves of the Female Genitourinary Tract

1977 • 192 citations

Evidence for a Specific Seminiferous Tubular Factor Affecting Follicle-Stimulating Hormone Secretion in Man

1972 • 191 citations

Follicular Plasminogen Activator: Involvement in Ovulation*

1985 • 191 citations

Hormonal Regulation, Tissue Distribution, and Content of Aromatase Cytochrome P450 Messenger Ribonucleic Acid and Enzyme in Rat Ovarian Follicles and Corpora Lutea: Relationship to Estradiol Biosynthesis*

1988 • 191 citations

Plasma Level of LH and FSH in Maturing Rats: Response to Hemigonadectomy

1972 • 188 citations

Epidermal Growth Factor Induces Maturation of Rat Follicle-Enclosed Oocytes*

1985 • 187 citations

Epidermal growth factor, its receptor, and related proteins

1986 • 186 citations

Treatment of Prostate Cancer with Gonadotropin-Releasing Hormone Agonists

1986 • 186 citations

INHIBITION OF OVARIAN AND TESTICULAR STEROIODOGENESIS BY EPIDERMAL GROWTH FACTOR

1981 • 184 citations

CULTURED GRANULOSA CELLS PRODUCE TWO PLASMINOGEN ACTIVATORS AND AN ANT IACTIVATOR, EACH REGULATED DIFFERENTLY BY GONADOTROPINS.

1985 • 181 citations

Chronic Human Chorionic Gonadotropin Admininstration in Normal Men: Evidence that Follicle-Stimulating Hormone Is Necessary for the Maintenance of Quatitatively Normal Spermatogenesis in Man *

1986 • 179 citations

A homodimer of the β-subunits of inhibin a stimulates the secretion of pituitary follicle stimulating hormone

1986 • 176 citations

Bovine Granulosa Cells Produce Basic Fibroblast Growth Factor*

1987 • 175 citations

STIMULATION OF LH FRAGMENTS WITH REDUCED BIOACTIVITY FOLLOWING GnRH AGONIST ADMINISTRATION IN WOMEN

1984 • 174 citations

Cholesterol Side-Chain Cleavage P450 Messenger Ribonucleic Acid: Evidence for Hormonal Regulation in Rat Ovarian Follicles and Constitutive Expression in Corpora Lutea*

1987 • 173 citations

The Relationship Between Germinal Cells and Serum FSH Levels in Males with Infertility¹

1974 • 169 citations

Radioimmunoassay for Human Follicle Stimulating Hormone

1967 • 167 citations

Human chorionic gonadotropin β-subunit is encoded by at least eight genes arranged in tandem and inverted pairs

1982 • 162 citations

Estrogens augment the stimulation of ovarian aromatase activity by follicle-stimulating hormone in cultured rat granulosa cells.

1982 • 162 citations

THE GONAD STIMULATING AND THE LUTEINIZING HORMONES OF THE ANTERIOR LOBE OF THE HYPOPHESIS

1931 • 161 citations

The Effect of Transforming Growth Factor-β on Follicle-Stimulating Hormone-Induced Differentiation of Cultured Rat Granulosa Cells*

1987 • 161 citations

alpha Subunit of rat pituitary glycoprotein hormones. Primary structure of the precursor determined from the nucleotide sequence of cloned cDNAs.

1982 • 160 citations

EVIDENCE THAT GRANULOSA CELL AROMATASE INDUCTION/ACTIVATION BY FOLLICLE-STIMULATING HORMONE IS AN ANDROGEN RECEPTOR-REGULATED PROCESS IN-VITRO

1981 • 156 citations

Monotropic Increase of Serum FSH Correlated with Low Sperm Count in Young Men with Idiopathic Oligospermia and Aspermia

1971 • 154 citations

Treatment of Prostatic Cancer with a Gonadotropin-Releasing Hormone Agonist Analog: Acute and Long Term Effects on Endocrine Functions of Testis Tissue*

1985 • 152 citations

Vasoactive Intestinal Peptide: A Novel Stimulator of Steroidogenesis by Cultured Rat Granulosa Cells1

1985 • 148 citations

Preparation of Antiserum to Rat Cytochrome P-450 Cholesterol Side Chain Cleavage, and Its Use for Ultrastructural Localization of the Immunoreactive Enzyme by Protein A-Gold Technique*

1986 • 145 citations

Autoradiographic Analysis of Gonadotropin Binding to Rat Ovarian Tissue Sections

1973 • 141 citations

PLASMA INHIBIN LEVELS DURING GONADOTROPIN-INDUCED OVARIAN HYPERSTIMULATION FOR IVF: A NEW INDEX OF FOLLICULAR FUNCTION?

1986 • 140 citations

ANTAGONISTIC INTERACTIONS OF TRANSFORMING GROWTH FACTORS IN THE REGULATION OF GRANULOSA CELL DIFFERENTIATION

1986 • 137 citations

Adenosine 3',5'-Monophosphate, Luteinizing Hormone Receptor, and Progesterone during Granulosa Cell Differentiation: Effects of Estradiol and Follicle- Stimulating Hormone*

1979 • 137 citations

Specific Insulin-Like Growth Factor (IGF) I- and II-Binding Sites on Rat Granulosa Cells: Relation to IGF Action*

1986 • 137 citations

Regulation of ovarian progestin production by epidermal growth factor in cultured rat granulosa cells.

1982 • 135 citations

Episodic Luteinizing Hormone (LH) Secretion and the Response of LH and Follicle-Stimulating Hormone to LH-Releasing Hormone in Aged Men: Evidence for Coexistent Primary Testicular Insufficiency and an Impairment in Gonadotropin Secretion*

1982 • 135 citations

Regulation by Follicle-Stimulating Hormone of the Synthesis of Aromatase Cytochrome P-450 in Human Granulosa Cells

1987 • 133 citations

Suppression of Ovulation Rate by Antibodies to Tissue-Type Plasminogen Activator and α₂-Antiplasmin*

1989 • 131 citations

DNA Sequence and Regional Assignment of the Human Follicle-Stimulating Hormone β-Subunit Gene to the Short Arm of Human Chromosome 11

1987 • 131 citations

The Immature Rat Ovary Is Innervated by Vasoactive Intestinal Peptide (VIP)-Containing Fibers and Responds to VIP with Steroid Secretion*

1986 • 126 citations

Interleukin-1 Inhibits Luteinization of Porcine Granulosa Cells in Culture

1988 • 125 citations

Inhibition of serum androgen levels by chronic intranasal and subcutaneous administration of a potent luteinizing hormone-releasing hormone (LH-RH) agonist in adult men

1982 • 125 citations

Structure and Function of the Gonadotropins

1979 • 121 citations

Ovarian epidermal growth factor-like activity. Concentrations in porcine follicular fluid during follicular enlargement

1987 • 120 citations

Renin-like activity in ovarian follicular fluid

1985 • 119 citations

The β-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus

1986 • 118 citations

Reproductive Hormones in Aging Men. II. Basal Pituitary Gonadotropins and Gonadotropin Responses to Luteinizing Hormone-Releasing Hormone

1982 • 117 citations

Naturally Occurring Antihormones: Secretion of FSH Antagonists by Women Treated with a GnRH Analog

1988 • 117 citations

The Effects of Ovariectomy, Estrogen Replacement, and Neuraminidase Treatment on the Properties of the Adenohypophysial Glycoprotein Hormones of the Rhesus Monkey

1976 • 115 citations

Hormonal Control of Epidermal Growth Factor Receptors by Gonadotropins during Granulosa Cell Differentiation

1987 • 114 citations

Cell-Specific Expression of Immunoreactive Cholesterol Side-Chain Cleavage Cytochrome P-450 during Follicular Development in the Rat Ovary*

1986 • 114 citations

OVARIAN TRANSFORMING GROWTH FACTOR-α GENE EXPRESSION: IMMUNOHISTOCHEMICAL LOCALIZATION TO THE THECAINTERSTITIAL CELLS

1987 • 113 citations

LHRH and its analogs : contraceptive and therapeutic applications

1984 • 111 citations

Transforming growth factor-beta modulates the high-affinity receptors for epidermal growth factor and transforming growth factor-alpha.

1985 • 111 citations

Development of Gonadotropin Regulation in the Prepubertal Mammal

1979 • 110 citations

Synergism between Granulosa and Theca-Interstitial Cells in Estrogen Biosynthesis by Gonadotropin-Treated Rat Ovaries: Studies on the Two-Cell, Two-Gonadotropin Hypothesis Using Steroid Antisera1

1986 • 109 citations

Granulosa Cell Aromatase Bioassay for Follicle-Stimulating Hormone: Validation and Application of the Method*

1986 • 108 citations

Plasminogen activator in the rat ovary. Production and gonadotropin regulation of the enzyme in granulosa and thecal cells.

1985 • 104 citations

Effect of very high dose D-leucine6-gonadotropin-releasing hormone proethylamide on the hypothalamic-pituitary testicular axis in patients with prostatic cancer.

1983 • 104 citations

A luteinizing hormone-releasing hormone agonist decreases biological activity and modifies chromatographic behavior of luteinizing hormone in man.

1984 • 99 citations

Beneficial effects of endotoxins

1984 • 98 citations

Immunocytochemical localization of inhibin in rat and human reproductive tissues

1987 • 98 citations

Report of the National Pituitary Agency Collaborative Study on the Radioimmunoassay of FSH and LH¹

1968 • 97 citations

Basic fibroblast growth factor as a regulator of ovarian granulosa cell differentiation: a novel non-mitogenic role

1988 • 97 citations

A Radioreceptor Assay for Follicle-Stimulating Hormone1

1975 • 96 citations

Mechanisms subserving the trophic actions of insulin on ovarian cells. In vitro studies using swine granulosa cells

1983 • 96 citations

Nucleotide sequence of the cDNA encoding the precursor of the beta subunit of rat lutropin.

1983 • 95 citations

INHIBITION OF SPERMATOGENESIS IN THE RAT BY TREATMENT WITH [D-Ala⁶,DES-GLY-NH₂¹⁰]LHRH ETHYLAMIDE

1978 • 95 citations

Follicle-Stimulating Hormone and Somatomedin-C Stimulate Inhibin Production by Rat Granulosa Cellsin Vitro*

1987 • 95 citations

Plasma prorenin response to human chorionic gonadotropin in ovarian-hyperstimulated women: correlation with the number of ovarian follicles and steroid hormone concentrations.

1987 • 94 citations

An Improved in Vitro Bioassay for Follicle-Stimulating Hormone (FSH): Suitable for Measurement of FSH in Unextracted Human Serum*

1987 • 94 citations

Molecular cloning of the human thyrotropin‐β subunit gene

1985 • 93 citations

Isolation and characterization of the rat thyrotropin beta-subunit gene. Differential regulation of two transcriptional start sites by thyroid hormone.

1987 • 92 citations

THE CHANGING RATIO OF SERUM BIOACTIVE TO IMMUNOREACTIVE FOLLICLE-STIMULATING HORMONE IN NORMAL MEN FOLLOWING TREATMENT WITH A POTENT GONADOTROPIN RELEASING HORMONE ANTAGONIST

1986 • 92 citations

Development of a Radioligand Tissue Receptor Assay for Human Follicle-Stimulating Hormone¹

1974 • 91 citations

Regulation of Human Gonadotropins: IV. Correlation of Serum Concentrations of Follicle Stimulating and Luteinizing Hormones During the Menstrual Cycle¹

1968 • 91 citations

Ovarian Thecal/Interstitial Cells Produce an Epidermal Growth Factor-Like Substance*

1987 • 91 citations

Coding sequences for vasoactive intestinal peptide and PHM-27 peptide are located on two adjacent exons in the human genome.

1985 • 91 citations

Amino acid sequence of the beta subunit of follicle-stimulating hormone from human pituitary glands.

1976 • 91 citations

A SENSITIVE AND SPECIFIC IN VITRO BIOASSAY METHOD FOR THE MEASUREMENT OF FOLLICLE-STIMULATING HORMONE ACTIVITY

1979 • 90 citations

Male and Female Forms of Human Follicle-Stimulating Hormone in Serum*

1982 • 89 citations

DIRECT ENHANCEMENT OF GONADOTROPIN-STIMULATED OVARIAN ESTROGEN BIOSYNTHESIS BY ESTROGEN AND CLOMIPHENE CITRATE

1982 • 89 citations

Rat Sertoli cells secrete a growth factor that blocks epidermal growth factor (EGF) binding to its receptor.

1986 • 88 citations

Immunohistochemical detection of inhibin in the gonad

1987 • 87 citations

Fibroblast growth factor as an intraovarian hormone: differential regulation of steroidogenesis by an angiogenic factor

1986 • 86 citations

Plasma and Urinary Follicle-Stimulating Hormone Levels in Oligospermia

1972 • 86 citations

Purification and characterization of hormone-regulated isoforms of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovaries.

1985 • 86 citations

Isolation and characterization of a complementary DNA specific for human aromatase-system cytochrome P-450 mRNA.

1986 • 86 citations

Age-related change in numbers of other interstitial cells in testes of adult men: evidence bearing on the fate of Leydig cells lost with increasing age

1985 • 83 citations

THERAPEUTIC POTENTIAL OF THE LHRH AGONIST, ICI 118630, IN THE TREATMENT OF ADVANCED PROSTATIC CARCINOMA

1983 • 83 citations

Experimentelle Untersuchungen über die Funktion und das Hormon des Ovariums

1925 • 83 citations

Characterization and Regulation of a Specific Cell Membrane Receptor for Somatomedin-C/Insulin-Like Growth Factor I in Cultured Rat Granulosa Cells*

1988 • 82 citations

Gonadal Function and the Biological and Physicochemical Properties of FollicleZ— Stimulating Hormone

1973 • 82 citations

Gonadotropins Regulate Plasminogen Activator Production by Rat Granulosa Cells*

1983 • 81 citations

Follicle-Stimulating Hormone Induces Transient Expression of the Protooncogene c-fos in Primary Sertoli Cell Cultures

1988 • 80 citations

Vasoactive intestinal peptide enhances aromatase activity in the neonatal rat ovary before development of primary follicles or responsiveness to follicle-stimulating hormone.

1987 • 80 citations

Insulin enhances FSH-stimulated steroidogenesis by cultured rat granulosa cells

1984 • 79 citations

α-Inhibin Gene Expression Occurs in the Ovine Adrenal Cortex, and is Regulated by Adrenocorticotropin

1987 • 78 citations

Median charge and charge heterogeneity of human pituitary FSH, LH and TSH

1985 • 78 citations

Serum Bioactive Follicle-Stimulating Hormone during the Human Menstrual Cycle and in Hyper- and Hypogonadotropic States: Application of a Sensitive Granulosa Cell Aromatase Bioassay*

1986 • 78 citations

Hormonal Effects of Gonadotropin-Releasing Hormone (GnRH) Agonist in the Human Male. III. Effects of Long Term Combined Treatment with GnRH Agonist and Androgen*

1985 • 77 citations

Gonadotropin regulation of tissue-type and urokinase-type plasminogen activators in rat granulosa and theca-interstitial cells during the periovulatory period

1987 • 76 citations

Secretion of follicle-stimulating hormone and production of inhibin are reciprocally related.

1987 • 75 citations

IMMUNIZATION AGAINST AN INHIBIN SUBUNIT PRODUCED BY RECOMBINANT DNA TECHNIQUES RESULTS IN INCREASED OVULATION RATE IN SHEEP

1987 • 75 citations

Inhibin: 1985 update on action and purification

1985 • 74 citations

Molecular Cloning and Nucleotide Sequence Analysis of Complementary Deoxyribonucleic Acid for the β-Subunit of Rat Follicle Stimulating Hormone

1987 • 73 citations

Role of the Serum Estrogen-Binding Protein in the Control of Tissue Estradiol Levels during Postnatal Development of the Female Rat*

1978 • 73 citations

Heterogeneity of rat FSH by chromatofocusing: studies on serum FSH, hormone released in vitro and metabolic clearance rates of its various forms [ill]

1985 • 72 citations

Inhibin: Studies of Stored and Secreted Forms by Biosynthetic Labeling and Immunodetection in Cultured Rat Granulosa Cells*

1988 • 71 citations

Regulation of inhibin production by rat granulosa cells

1987 • 71 citations

Isolation and Nucleotide Sequence Analysis of a Cloned cDNA Encoding the β-Subunit of Bovine Follicle-Stimulating Hormone

1986 • 70 citations

The Glycoprotein α-Subunit is Critical for Secretion and Stability of the Human Thyrotropin β-Subunit

1988 • 70 citations

Reversible inhibition of testicular function by a gonadotropin hormone-releasing hormone antagonist in monkeys (Macaca fascicularis)

1984 • 69 citations

Studies on pituitary follitropin X. Biochemical, receptor binding and immunological properties of deglycosylated ovine hormone

1982 • 68 citations

Hormonal regulation of tissue plasminogen activator secretion and mRNA levels in rat granulosa cells.

1987 • 68 citations

Inhibin a-subunit gene expression in the ovaries of immature female rats is stimulated by pregnant mare serum gonadotrophin

1986 • 67 citations

Gonad-Pituitary Feedback Involves Qualitative Change: Androgens Alter the Type of FSH Secreted by the Rat Pituitary¹²

1974 • 67 citations

Qualitative Changes in the Pituitary Gonadotropins of the Male Rhesus Monkey Following Castration

1976 • 67 citations

TREATMENT OF ADVANCED PROSTATIC CANCER WITH LHRH ANALOGUE ICI 118630: CLINICAL RESPONSE AND HORMONAL MECHANISMS

1983 • 67 citations

Naturally Occurring Forms of Thyrotropin with Low Bioactivity and Altered Carbohydrate Content Act as Competitive Antagonists to More Bioactive Forms

1983 • 66 citations

Deglycosylated human follitropin: characterization and effects on adenosine cyclic 3',5'-phosphate production in porcine granulosa cells

1986 • 66 citations

Substance P- and Vasoactive Intestinal Peptide-Containing Fibers Reach the Ovary by Independent Routes*

1986 • 65 citations

Identification of Subpopulations of Rat Granulosa Cells: Sedimentation Properties and Hormonal Responsiveness*

1985 • 65 citations

Transforming growth factor‐α attenuates the acquisition of aromatase activity by cultured rat granulosa cells

1987 • 64 citations

Gonadotropin-Releasing Hormone Induces Ovulation in Hypophysectomized Rats: Studies on Ovarian Tissue- Type Plasminogen Activator Activity, Messenger Ribonucleic Acid Content, and Cellular Localization*

1988 • 64 citations

Sensitive in vitro Bioassay for the Measurement of Serum Follicle-Stimulating Hormone

1985 • 64 citations

Age-related changes in the feedback regulation of gonadotrophin secretion by sex steroids in men

1981 • 62 citations

Hormonal Regulation of 3′,5′-Adenosine Monophosphate Phosphodiesterases in Cultured Rat Granulosa Cells*

1984 • 59 citations

A New Sensitive Bio-ass ay for Follicle-Stimulating Hormone (FSH)

1964 • 59 citations

Plasma LH and FSH Levels in Subfertile Men

1974 • 59 citations

Sexual Maturation in Female Rats: Time-Related Changes in the Isoelectric Focusing Pattern of Anterior Pituitary Follicle-Stimulating Hormone 1

1983 • 59 citations

Luteinizing and follicle-stimulating hormones. Cell-free translations of messenger RNAs coding for subunit precursors.

1980 • 58 citations

Cloning of the Human Thyrotropin β-Subunit Gene and Transient Expression of Biologically Active Human Thyrotropin after Gene Transfection

1988 • 57 citations

Effect of an antagonistic analog of gonadotropin releasing hormone upon ovarian granulosa cell function

1979 • 56 citations

A cell culture assay for follicle-stimulating hormone.

1978 • 56 citations

Combined Treatment with an LHRH Agonist and Testosterone in Man Reversible Oligozoospermia without Impotence

1983 • 55 citations

Studies on pituitary follitropin XI. Induction of hormonal antagonistic activity by chemical deglycosylation

1982 • 54 citations

Unusual Anti-Reproductive Properties of the Analog [d-Leu6,Des-Gly-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif" overflow="scroll"><mml:msup><mml:msub><mml:mrow><mml:mi mathvariant="normal">N</mml:mi><mml:mi mathvariant="normal">H</mml:mi></mml:mrow><mml:mn>2</mml:mn></mml:msub><mml:mn>10</mml:mn></mml:msup></mml:math>]-Luteinizing Hormone-Releasing Hormone Ethylamide in Male Rats

1978 • 53 citations

Cloning and Characterization of a cDNA for Rat Tissue-Type Plasminogen Activator

1988 • 53 citations

Control of Transferrin mRNA Synthesis in Sertoli Cells ^a

1984 • 52 citations

Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.

1986 • 51 citations

Monitoring the Menstrual Cycle of Humans and Lowland Gorillas Based on Urinary Profiles of Bioactive Follicle-Stimulating Hormone and Steroid Metabolites*

1987 • 51 citations

Serum FSH and LH in Constant Light-Induced Persistent Estrus: Short-Term and Long-Term Studies

1971 • 50 citations

Studies on the Hormonal Regulation of Plasminogen Activator Production in the Rat Ovary*

1986 • 50 citations

Synthesis of the Cholesterol Side-Chain Cleavage Enzymes in Cultured Rat Ovarian Granulosa Cells: Induction by Follicle-Stimulating Hormone and Dibutyryl Adenosine 3′,5′-Monophosphate*

1986 • 49 citations

Evidence for a conformational change in deglycosylated glycoprotein hormones

1985 • 48 citations

Nucleotide Sequence of the Bovine Gene for Follicle-Stimulating Hormone β-Subunit

1988 • 47 citations

FSH STIMULATION OF³H-GLUCOSAMINE-INCORPORATION INTO PROTEOGLYCANS BY PORCINE GRANULOSA CELLS IN VITRO*

1979 • 47 citations

Serum Bioactive and Immunoreactive Follicle-Stimulating Hormone in Prostatic Cancer Patients During Gonadotropin-Releasing Hormone Agonist Treatment and After Orchidectomy*

1988 • 46 citations

Hormonal Regulation of Tissue-Type Plasminogen Activator Messenger Ribonucleic Acid Levels in Rat Granulosa Cells: Mechanisms of Induction by Follicle-Stimulating Hormone and Gonadotropin Releasing Hormone

1988 • 46 citations

Production of all follicle-stimulating hormone isohormones from a purified preparation by neuraminidase digestion 1

1984 • 46 citations

Molecular composition of luteinizing hormone and folliclestimulating hormone in commercial gonadotropin preparations

1986 • 45 citations

Serum Bioactive and Immunoreactive Follicle-Stimulating Hormone Levels and the Response to Clomiphene in Healthy Young and Elderly Men*

1987 • 44 citations

BIOLOGICAL STUDIES OF THE GONADOTROPIC PRINCIPLES IN SHEEP PITUITARY SUBSTANCE¹

1939 • 44 citations

Porcine Follicular Fluid Contains Both Follicle- Stimulating Hormone Agonist and Antagonist Activities*

1987 • 43 citations

Development of Neural Regulation of Follicle Stimulating Hormone (FSH) Secretion

1972 • 42 citations

Discrepancies Between Radioimmunoassays and Bioassay for Rat FSH: Evidence that Androgen Treatment and Withdrawal Can Alter Biossay—Immunoassay Ratios1

1973 • 42 citations

Electrofocusing fractionation and characterization of pituitary follicle-stimulating hormone from male and female rats

1983 • 41 citations

Effects of oestradiol, phenobarbitone and luteinizing hormone releasing hormone upon the isoelectric profile of pituitary follicle-stimulating hormone in ovariectomized hamsters

1983 • 41 citations

Cloning and DNA sequence analysis of the cDNA for the precursor of porcine follicle stimulating hormone (FSH) β subunit

1988 • 41 citations

Current Therapy of Infertility--3

1989 • 40 citations

Studies on the Structure and Function of Interstitial Cell-Stimulating Hormone

1973 • 39 citations

Gonadotropin-releasing hormone analogues for palliation of carcinoma of the prostate

1983 • 39 citations

Ovarian renin gene expression is regulated by follicle-stimulating hormone

1987 • 38 citations

Species Differences in Follicle-Stimulating Hormone as Revealed by the Slope in the Steelman-Pohley Assay1

1963 • 38 citations

The Dependency of Bioactive Follicle-Stimulating Hormone Secretion on Gonadotropin-Releasing Hormone in Hypogonadal and Cycling Women*

1988 • 37 citations

BIOLOGICAL AND IMMUNOLOGICAL PROPERTIES OF DIFFERENT MOLECULAR SPECIES OF HUMAN FOLLICLE-STIMULATING HORMONE: ELECTROFOCUSING PROFILES OF EIGHT HIGHLY PURIFIED PREPARATIONS

1982 • 37 citations

Cyclic AMP production in isolated rat seminiferous tubule cell preparations: A potential assay for follicle stimulating hormone

1975 • 37 citations

Production of human thyroid-stimulating hormone in Chinese hamster ovary cells

1987 • 35 citations

Suppression of Plasma Gonadotropins and Testosterone in Adult Male Monke(Macaca fascicularis) by a Potent Inhibitory Analog of Gonadotropin-Releasing Hormone*

1986 • 34 citations

Primary structure of the ovine pituitary follitropin α-subunit

1981 • 34 citations

Effects of Vasoactive Intestinal Polypeptide upon Ovarian Steroids, Ovum Transport and Fertility in the Rabbit 1

1983 • 34 citations

Serum Bioactive Follicle-Stimulating Hormone in Men with Idiopathic Azoospermia and Oligospermia

1987 • 34 citations

Microheterogeneity of anterior pituitary FSH in the male rat: isoelectric focusing pattern throughout sexual maturation

1986 • 31 citations

Evidence for a Role of Estrogen in the Ovarian Augmentation Reaction

1972 • 31 citations

Physical Characterization of hFSH and Its Desialylation Products by Isoelectric Focusing and Electrophoresis in Polyacrylamide Gel

1973 • 31 citations

Characterization of Recombinant DNA Derived—Human Luteinizing Hormone In Vitro and In Vivo

1988 • 29 citations

Relative Potencies of Gonadotropin-Releasing Hormone Agonists and Antagonists on Ovarian and Pituitary Functions*

1983 • 28 citations

The effect of cyanide and ferricyanide on the activity of the dissimilatory nitrate reductase of Escherichia coli.

1982 • 28 citations

A SIMPLE AND RAPID METHOD USING POLYETHYLENIMINE-TREATED FILTERS FOR ASSAY OF SOLUBILIZED LH/hCG RECEPTORS

1985 • 28 citations

Effect of diverse mammalian gonadotropins on estrogen and progesterone production by cultured rat granulosa cells

1983 • 27 citations

Vasoactive intestinal peptide stimulates plasminogen activator activity by cultured rat granulosa cells and cumulus-oocyte complexes

1987 • 27 citations

Evidence for diverse structural variations of the forms of human FSH within and between pituitaries

1987 • 27 citations

Vasoactive Intestinal Peptide Regulates Cholesterol Side-Chain Cleavage Cytochrome P-450 (P-450scc) Gene Expression in Granulosa Cells from Immature Rat Ovaries

1987 • 27 citations

Heterogeneity of Sperm Density Profiles Following 16‐Week Therapy with Continuous Infusion of High‐dose LHRH Analog Plus Testosterone

1986 • 26 citations

Pituitary FSH Content in Female Rats at Various Ages

1968 • 25 citations

Forskolin and phosphodiesterase inhibitors stimulate rat granulosa cell differentiation

1984 • 25 citations

Maintenance of the Ratio of Bioactive to Immunoreactive Follicle-Stimulating Hormone in Normal Men During Chronic Luteinizing Hormone-Releasing Hormone Agonist Administration*

1988 • 24 citations

Primary structure of the ovine pituitary follitropin β-subunit

1981 • 24 citations

Glucocorticoids Stimulate Plasminogen Activator Production by Rat Granulosa Cells*

1989 • 24 citations

Improved in vitro Bioassay of Follitropin

1982 • 23 citations

Bioactive Follicle-Stimulating Hormone Levels in Serum and Urine of Male and Female Rats from Birth to Prepubertal Period1

1988 • 22 citations

The Presence of Two Species of Follicle-Stimulating Hormone within Hamster Anterior Pituitary Glands as Disclosed by Concanavalin A Chromatography*

1981 • 21 citations

Molecular cloning of DNA complementary to bovine adrenal P450scc mRNA

1984 • 20 citations

Physical properties of human follicle-stimulating hormone

1971 • 20 citations

Labeling of bovine corpus luteal plasma membrane human chorionic gonadotropin or luteinizing hormone (hCGLH) receptor and its purification and properties

1977 • 20 citations

LUTEINIZING HORMONE RELEASING HORMONE STIMULATES PLASMINOGEN ACTIVATOR PRODUCTION BY RAT GRANULOSA CELLS

1983 • 18 citations

Pituitary‐Testicular Function of Prostatic Cancer Patients During Treatment with a Gonadotropin‐Releasing Hormone Agonist Analog II. Endocrinology and Histology of the Testis

1987 • 16 citations

Modulation of plasminogen activation by glucocorticoid hormones in the rat granulosa cell

1987 • 15 citations

THE EFFECT OF DIETHYLSTILBESTROL ON THE IMMATURE RAT OVARY¹

1961 • 14 citations

DISCREPANCIES AND SIMILARITIES OF SERUM FSH AND LH PATTERNS AS EVALUATED BY DIFFERENT ASSAY METHODS

1969 • 13 citations

Ovarian Weight Response to Varying Doses of Estrogens in Intact and Hypophysectomized Rats.

1961 • 13 citations

Uterine Weight of the Immature Rat as a Measure of Augmentation of Pituitary Gonadotrophins by Human Chorionic Gonadotrophin (HCG)

1967 • 13 citations

A COMPARISON OF BIOLOGIC AND IMMUNOLOGIC POTENCY ESTIMATES OF HUMAN LUTEINIZING (LH) AND FOLLICLE STIMULATING (FSH) HORMONES

1969 • 13 citations

Estrogens, Progestogens, and Androgens Enhance the Follicle-Stimulating Hormone-Stimulated Plasminogen Activator Production by Cultured Rat Granulosa Cells*

1987 • 12 citations

Luteinizing Hormone Activity of Human Pituitary Gonadotropin as Determined by the Ventral Prostate Weight and the Ovarian Ascorbic Acid Depletion Methods of Assay

1964 • 10 citations

Studies on the Biological Properties and Gel Filtration Behavior of Pituitary and Serum Follicle Stimulating Hormone of Infantile Female Rats¹

1977 • 10 citations

Decision Making in Infertility

1989 • 9 citations

Comparisons of Pituitary:Serum Luteinizing Hormone (LH) Ratios in the Castrated Rat by Radioimmunoassay and OAAD Bioassay

1971 • 9 citations

STUDIES ON THE RAT OVARIAN AUGMENTATION METHOD FOR FOLLICLE STIMULATING HORMONE

1972 • 8 citations

Use of Antisera to Follicle-Stimulating Hormone (FSH) to Detect Non-FSH Factors in Human Serum which Modulate Rat Granulosa Cell Steroidogenesis*

1985 • 8 citations

THE RAT OVARIAN AUGMENTATION METHOD FOR FOLLICLE STIMULATING HORMONE

1972 • 7 citations

Hormonal and Immunological Characterization of the Cell-Associated Plasminogen Activators Produced by Cultured Rat Granulosa Cells

1987 • 4 citations