Expression of Granulocyte-Macrophage Colony-Stimulating Factor Receptors in Human Prostate Cancer

LNCaP model of human prostatic carcinoma.

1983 • 1,749 citations

Cytokine receptor signalling

1995 • 1,242 citations

Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor

1992 • 841 citations

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

1989 • 711 citations

Granulocyte- and granulocyte– macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate

1989 • 652 citations

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

1990 • 650 citations

Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors

1991 • 617 citations

Molecular physiology of granulocyte-macrophage colony-stimulating factor

1991 • 598 citations

Molecular physiology of granulocyte-macrophage colony-stimulating factor

1991 • 505 citations

Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation.

1992 • 365 citations

Various human hematopoietic growth factors (interleukin-3, GM-CSF, G- CSF) stimulate clonal growth of nonhematopoietic tumor cells [see comments]

1989 • 294 citations

Signal transduction of the human granulocyte-macrophage colony- stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins

1990 • 294 citations

Human granulocyte-macrophage colony-stimulating factor is a growth factor active on a variety of cell types of nonhemopoietic origin.

1988 • 238 citations

Nonhematopoietic tumor cells express functional GM-CSF receptors

1989 • 212 citations

Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase

1992 • 210 citations

High-affinity binding of granulocyte-macrophage colony-stimulating factor to normal and leukemic human myeloid cells.

1986 • 195 citations

Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase

1992 • 176 citations

c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3.

1993 • 170 citations

Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members.

1992 • 147 citations

Clinical applications of hematopoietic growth factors.

1995 • 143 citations

Characterization of the cell surface receptor for human granulocyte/macrophage colony-stimulating factor.

1986 • 141 citations

Multiple Hematopoietic Growth Factors Signal Through Tyrosine Phosphorylation

1990 • 125 citations

Residue 21 of human granulocyte-macrophage colony-stimulating factor is critical for biological activity and for high but not low affinity binding.

1992 • 112 citations

Human granulocyte-macrophagecolony-stimulating factor is a growth factor active on avariety of cell types of nonhemopoietic origin

1988 • 106 citations

Reconstituted human granulocyte-macrophage colony-stimulating factor receptor transduces growth-promoting signals in mouse NIH 3T3 cells: comparison with signalling in BA/F3 pro-B cells.

1993 • 86 citations

Identification and partial characterization of the secretory glycoproteins of the bovine subcommissural organ-Reissner's fiber complex. Evidence for the existence of two precursor forms

1991 • 84 citations

Low-affinity placenta-derived receptors for human granulocyte-macrophage colony-stimulating factor can deliver a proliferative signal to murine hemopoietic cells.

1990 • 75 citations

Differentiation-associated expression of two functionally distinct classes of granulocyte-macrophage colony-stimulating factor receptors by human myeloid cells.

1990 • 75 citations

Characterization and molecular features of the cell surface receptor for human granulocyte-macrophage colony-stimulating factor.

1990 • 74 citations

Granulocyte-macrophage colony-stimulating factor-induced protein tyrosine phosphorylation of microtubule-associated protein kinase in human neutrophils.

1992 • 66 citations

The alpha subunit of the human granulocyte-macrophage colony-stimulating factor receptor signals for glucose transport via a phosphorylation-independent pathway.

1994 • 60 citations

Identification and characterization of a low-affinity granulocyte- macrophage colony-stimulating factor receptor on primary and cultured human melanoma cells

1991 • 59 citations

Granulocyte-macrophage colony-stimulating factor activates microtubule- associated protein 2 kinase in neutrophils via a tyrosine kinase- dependent pathway

1992 • 57 citations

The human granulocyte-macrophage colony-stimulating factor receptor is capable of initiating signal transduction in NIH3T3 cells.

1993 • 52 citations

Establishment of eosinophilic sublines from human promyelocytic leukemia (HL-60) cells: demonstration of multipotentiality and single- lineage commitment of HL-60 stem cells

1986 • 50 citations

A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth.

1993 • 46 citations

Differential regulation of early response genes and cell proliferation through the human granulocyte macrophage colony-stimulating factor receptor: selective activation of the c-fos promoter by genistein.

1993 • 44 citations

Identification and characterization of a high-affinity granulocyte- macrophage colony-stimulating factor receptor on primary rat oligodendrocytes

1993 • 44 citations

Production and response of human prostate cancer cell lines to granulocyte macrophage‐colony stimulating factor

1994 • 43 citations

Frequent expression of receptors for granulocyte‐macrophage colony‐stimulating factor on human nonhematopoietic tumor cell lines

1990 • 42 citations

Therapeutic efficacy of recombinant tumor necrosis factor alpha in an experimental model of human prostatic carcinoma.

1990 • 38 citations

Granulocyte-macrophage colony-stimulating factor signals for increased glucose uptake in human melanoma cells

1995 • 37 citations

Effects of cytokines on in vitro colony formation of primary human tumour specimens

1990 • 36 citations

Membrane-associated and soluble granulocyte/macrophage-colony-stimulating factor receptor alpha subunits are independently regulated in HL-60 cells.

1995 • 33 citations

Expression of monocyte/macrophage growth factors and receptors in the central nervous system.

1993 • 32 citations

Transcription of genes encoding granulocyte-macrophage colony-stimulating factor, interleukin 3, and interleukin 6 receptors and lack of proliferative response to exogenous cytokines in nonhematopoietic human malignant cell lines.

1993 • 31 citations

The use of colony stimulating factors in marrow transplantation

1993 • 18 citations

Stimulation of colony formation of various human carcinoma cell lines by rhGM-CSF and rhIL-3

1990 • 18 citations