Mechanism of inhibition reaction of acetylcholinesterase by phenyl N-methylcarbamates

Partition coefficients and their uses

1971 • 4,444 citations

Aromatic substituent constants for structure-activity correlations

1973 • 1,189 citations

Rates and equilibria of organic reactions

1963 • 946 citations

Studies of hydrogen-bonded complex formation with p-fluorophenol. V. Linear free energy relationships with OH reference acids

1969 • 245 citations

Resonance Effect in Hammett Relationship. II. Sigma Constants in Electrophilic Reactions and their Intercorrelation

1959 • 180 citations

Steric parameters in drug design. Monoamine oxidase inhibitors and antihistamines

1969 • 177 citations

The linear free-energy relation between partition coefficients and the binding, and conformational perturbation of macromolecules by small organic compounds

1968 • 157 citations

Carbamyl Derivatives of Acetylcholinesterase

1961 • 143 citations

The Use of Substituent Constants and Regression Analysis in the Study of Enzymatic Reaction Mechanisms

1965 • 103 citations

Insecticide Structure and Activity, Insecticidal Activity of Carbamate Cholinesterase Inhibitors

1954 • 101 citations

Structure-activity relationships for insecticidal carbamates.

1971 • 98 citations

The use of substituent constants in the study of structure-activity relationships in cholinesterase inhibitors

1966 • 87 citations

Relationships between the structure of organophosphorus compounds and their activity as acetylcholinesterase inhibitors.

1971 • 65 citations

The reaction of carbamates with cholinesterase.

1966 • 55 citations

Chymotrypsin-catalyzed phenyl ester hydrolysis. Evidence for electrophilic assistance on carbonyl oxygen

1970 • 43 citations

Ortho effect in hydrolysis of phenyl esters

1975 • 42 citations

Structure-Reactivity Correlations and General Acid-Base Catalysis in Enzymic Transacylation Reactions

1972 • 35 citations

Carbamylation and affinity constants of some carbamate inhibitors of acetylcholinesterase and their relation to analogous substrate constants

1970 • 34 citations

Alkaline hydrolysis, anticholinesterase, and insecticidal properties of some nitro-substituted phenyl carbamates

1967 • 31 citations

Reexamination of electronic effects in ring-substituted phenyl esters. Correlation of spectral and kinetic properties with .sigma.0

1973 • 26 citations

Electron-donor and affinity constants and their application to the inhibition of acetylcholinesterase by carbamates

1975 • 23 citations

Kinetic constants for the inhibition of acetylcholinesterase by phenyl carbamates

1976 • 23 citations

Charge transfer in cholinesterase inhibition. Role of the conjugation between carbamyl and aryl groups of aromatic carbamates

1973 • 19 citations

Physicochemical Parameters for Structure-Activity-Studies of Substituted Phenyl N-Methylcarbamates

1974 • 19 citations

Insecticide Activity and Structure, Para-Substituted Meta-Xylenyl Diethyl Phosphates and N-Methylcarbamates as Anticholinesterases and Insecticides

1964 • 17 citations

The role of charge-transfer complex formation in the inhibition of acetylcholinesterase by aromatic carbamates

1972 • 13 citations