Detection of Viral Nucleic Acids by in Situ Hybridization

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Manual of histologic staining methods of the Armed forces institute of pathology

1968 • 4,954 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

1974 • 3,882 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

FORMATION AND DETECTION OF RNA-DNA HYBRID MOLECULES IN CYTOLOGICAL PREPARATIONS

1969 • 1,214 citations

Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes.

1981 • 1,165 citations

Chromosomal Localization of Mouse Satellite DNA

1970 • 1,119 citations

Techniques of autoradiography

1967 • 1,044 citations

Immunological method for mapping genes on Drosophila polytene chromosomes.

1982 • 772 citations

Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide

1977 • 713 citations

RNA-DNA Hybrids at the Cytological Level

1969 • 592 citations

Location of Ribosomal DNA in the Human Chromosome Complement

1972 • 554 citations

EB Viral Genomes in Epithelial Nasopharyngeal Carcinoma Cells

1973 • 488 citations

Chromosomal and Nuclear Location of Mouse Satellite DNA in Individual Cells

1970 • 470 citations

Detection of viral sequences of low reiteration frequency by in situ hybridization.

1978 • 458 citations

Acetylation of chromosome squashes of Drosophila melanogaster decreases the background in autoradiographs from hybridization with [125I]-labeled RNA.

1978 • 336 citations

Two human c-onc genes are located on the long arm of chromosome 8.

1982 • 329 citations

A new method for fluorescence microscopical localization of specific DNA sequences by in situ hybridization of fluorochrome-labelled RNA

1980 • 325 citations

High resolution detection of DNA–RNA hybrids in situ by indirect immunofluorescence

1977 • 305 citations

Actin gene expression visualized in chicken muscle tissue culture by using in situ hybridization with a biotinated nucleotide analog.

1982 • 295 citations

Localization of the human insulin gene to the distal end of the short arm of chromosome 11.

1981 • 285 citations

Theiler's Virus-Induced Demyelination: Prevention by Immunosuppression

1976 • 242 citations

The ribonuclease activity of crystallized pancreatic deoxyribonuclease

1966 • 211 citations

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization

1982 • 192 citations

Localization of a unique gene by direct hybridization in situ.

1981 • 178 citations

Replication of EBV in epithelial cells during infectious mononucleosis

1977 • 173 citations

Measles Virus Nucleotide Sequences: Detection by Hybridization in Situ

1981 • 167 citations

Autoradiographic Detection of Molecular Hybrids between rRNA and DNA in Tissue Sections

1970 • 165 citations

Detection of hepatitis B virus DNA in hepatocytes, bile duct epithelium, and vascular elements by in situ hybridization.

1983 • 165 citations

Slow Persistent Infection Caused by Visna Virus: Role of Host Restriction

1977 • 163 citations

Comparative Diagnosis of Viral Diseases

1982 • 161 citations

The reaction of formaldehyde with nucleotides and T2 bacteriophage DNA

1961 • 160 citations

Isolation and identification of cross-links from formaldehyde-treated nucleic acids

1980 • 158 citations

Theiler's virus persists in glial cells during demyelinating disease

1981 • 153 citations

A new era in mammalian gene mapping: somatic cell genetics and recombinant DNA methodologies

1981 • 152 citations

High Speed Scintillation Autoradiography

1975 • 145 citations

PHYSIOCHEMICAL AND BIOLOGICAL PROPERTIES OF THE MAJOR BASIC PROTEIN FROM GUINEA PIG EOSINOPHIL GRANULES

1974 • 142 citations

Visna DNA synthesis and the tempo of infection in vitro

1982 • 121 citations

Detection of herpes simplex RNA in human sensory ganglia

1979 • 114 citations

Gene expression in visna virus infection in sheep

1981 • 106 citations

In situ hybridization of DNA sequences in human metaphase chromosomes visualized by an indirect fluorescent immunocytochemical procedure

1982 • 103 citations

Localisation of cellular globin messenger RNA by in situ hybridisation to complementary DNA

1973 • 98 citations

Quantitative in situ hybridization of ribosomal RNA species to polytene chromosomes of Drosophila melanogaster

1977 • 97 citations

Limited transcription of the herpes simplex virus genome when latent in human sensory ganglia

1982 • 90 citations

Evidence for and Localization of Vegetative Viral DNA Replication by Autoradiographic Detection of RNA·DNA Hybrids in Sections of Tumors Induced by Shope Papilloma Virus

1971 • 83 citations

Medical microbiology and infectious diseases.

1981 • 82 citations

In vitro assembly of poliovirus-related particles

1968 • 81 citations

Ultrastructural antibody localization of alpha2-macroglobulin in membrane-limited vesicles in cultured cells.

1978 • 73 citations

In situ Hybridization of Adenovirus RNA and DNA

1972 • 72 citations

IN SITU LOCALIZATION OF GLOBIN MESSENGER RNA FORMATION

1974 • 58 citations

Cytochemical hybridization with fluorochrome-labeled RNA. I. Development of a method using nucleic acids bound to agarose beads as a model.

1981 • 54 citations

Herpesvirus-specific RNA and protein in carcinoma of the uterine cervix.

1982 • 51 citations

Quantitative Analysis of Steroid Autoradiograms,

1981 • 51 citations

Localization of the 5S RNA genes in Zea mays by RNA-DNA hybridization in situ

1974 • 51 citations

Genes Coding for Histone Proteins in Man Are Located on the Distal End of the Long Arm of Chromosome 7

1979 • 51 citations

Cytochemical hybridization with fluorochrome-labeled RNA. II. Applications.

1981 • 51 citations

IN SITU LOCALIZATION OF GLOBIN MESSENGER RNA FORMATION

1974 • 49 citations

Detection of hepatitis b virus dna sequences in infected hepatocytes by in situ cytohybridisation

1981 • 47 citations

Measles Virus Genome in Infections of the Central Nervous System

1981 • 40 citations

Persistence and Expression of Marek's Disease Virus DNA in Tumour Cells and Peripheral Nerves Studied by in situ Hybridization

1981 • 39 citations

Murine cytomegalovirus infects spermatogenic cells.

1979 • 38 citations

Chromosome 1 contains the endogenous RAV-0 retrovirus sequences in chicken cells.

1979 • 37 citations

Ultrastructural localization of SV40 viral DNA in cells, during lytic infection, by in situ molecular hybridization

1974 • 35 citations

RNA-dependent DNA polymerase of avian sarcoma virus B77. II. Comparison of the catalytic properties of the alpha, beta2, and alphabeta enzyme forms.

1977 • 32 citations

Detection of AKR MuLV-specific RNA in AKR mouse cells by in situ hybridization

1979 • 31 citations

Location of the 18/28S ribosomal RNA genes in two Hawaiian Drosophila species by monoclonal immunological identification of RNA.DNA hybrids in situ.

1981 • 30 citations

The Localization of Transfer RNA ₅ ^Lys Genes in Drosophila melanogaster

1974 • 30 citations

Persistence of CMV genome in lymphoid cells after congenital infection

1975 • 30 citations

Vertical Transmission of Murine Cytomegalovirus

1979 • 29 citations

Tissue fixation with diimidoesters as an alternative to aldehydes. II. Cytochemical and biochemical studies of rat liver fixed with dimethylsuberimidate.

1976 • 26 citations

Detection of Epstein-Barr virus (EBV) DNA sequences using in situ hybridization

1978 • 25 citations

A comparison of the high molecular weight RNAs of visna virus and Rous sarcoma virus

1974 • 24 citations

Simple rapid method for the synthesis of radioactively labeled cDNA hybridization probes utilizing bacteriophage M13mp7.

1982 • 24 citations

Virus-specific transcription and translation in organs of BALB / Mo mice: Comparative study using quantitative hybridization, in Situ hybridization, and immunocytochemistry

1982 • 20 citations

A comparative study of in situ hybridization procedures using cRNA applied to Drosophila hydei salivary gland chromosomes

1974 • 17 citations

Detection of Viral DNA Sequences in Adenovirus-Transformed Cells by In Situ Hybridization

1973 • 17 citations

Detection and Localization of Virus-Specific DNA by In Situ Hybridization of Cells During Infection and Rapid Transformation by the Murine Sarcoma-Leukemia Virus

1974 • 15 citations

Glutaraldehyde nonfixation of isolated viral and yeast RNAs.

1980 • 14 citations

Formamide denaturation of chromosomal DNA for in situ hybridization and C-band preparation in the guinea pig, Cavia porcellus

1976 • 11 citations

Scintillation autoradiography at the light microscopic level: A review

1981 • 9 citations

Chromic-Acid Formaldehyde Fixation of Nucleic Acids of Bacteriophage 6 and Infectious Bovine Rhinotracheitis Virus

1978 • 9 citations

In situ hybridization: general infectivity assay for retroviruses

1982 • 6 citations