Cytochemical hybridization with fluorochrome-labeled RNA. I. Development of a method using nucleic acids bound to agarose beads as a model.

A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane

1965 • 1,981 citations

[31] Affinity chromatography

1971 • 1,407 citations

FORMATION AND DETECTION OF RNA-DNA HYBRID MOLECULES IN CYTOLOGICAL PREPARATIONS

1969 • 1,214 citations

Chromosomal Localization of Mouse Satellite DNA

1970 • 1,119 citations

Fluorescent Protein Tracing

1965 • 708 citations

RNA-DNA Hybrids at the Cytological Level

1969 • 592 citations

Location of Ribosomal DNA in the Human Chromosome Complement

1972 • 554 citations

MOLECULAR HYBRIDIZATION OF RADIOACTIVE DNA TO THE DNA OF CYTOLOGICAL PREPARATIONS

1969 • 532 citations

Detection of viral sequences of low reiteration frequency by in situ hybridization.

1978 • 458 citations

Localization of RNA from heat-induced polysomes at puff sites in Drosophila melanogaster.

1975 • 332 citations

Cytological localization of DNA complementary to ribosomal RNA in polytene chromosomes of Diptera

1970 • 272 citations

A novel method of activation of cross-linked agaroses with 1,1'-carbonyldiimidazole which gives a matrix for affinity chromatography devoid of additional charged groups.

1979 • 258 citations

Analysis of drosophila mRNA by in situ hybridization: Sequences transcribed in normal and heat shocked cultured cells

1975 • 240 citations

Location of the genes for 5S ribosomal RNA in Xenopus laevis

1973 • 214 citations

Location of Satellite and Homogeneous DNA Sequences on Human Chromosomes

1971 • 208 citations

Covalent Attachment of DNA to Agarose

1975 • 207 citations

Localization of 5 S RNA Genes on Drosophila Chromosomes by RNA-DNA Hybridization

1970 • 206 citations

Optical studies of the interaction of 4?-6-diamidino-2-phenylindole with DNA and metaphase chromosomes

1977 • 166 citations

Protein binding by agarose carrying hydrophobic groups in conjunction with charges

1973 • 163 citations

Ecdysone-stimulated RNA synthesis in imaginal discs of Drosophila melanogaster

1976 • 161 citations

“Repetitive” DNA in higher organisms

1971 • 150 citations

Studies on the bacteriophage MS2. IV. The 3'-OH terminal undecanucleotide sequence of the viral RNA chain.

1967 • 126 citations

Ribosomal DNA Connectives between Human Acrocentric Chromosomes

1973 • 109 citations

Localisation of cellular globin messenger RNA by in situ hybridisation to complementary DNA

1973 • 98 citations

Polynucleotides

1966 • 97 citations

Quantitative in situ hybridization of ribosomal RNA species to polytene chromosomes of Drosophila melanogaster

1977 • 97 citations

The Reaction of Methylamine with Periodate-Oxidized Adenosine 5'-Phosphate

1963 • 89 citations

PARTIAL PURIFICATION OF SOLUBLE RNA

1960 • 87 citations

Locations of a Human Satellite DNA in Human Chromosomes

1972 • 83 citations

Detection of Polyoma Virus DNA in PML-Brain Tissue by (in situ) Hybridization

1979 • 76 citations

Studies of Transfer RNA Tertiary Structure by Singlet-Singlet Energy Transfer

1974 • 62 citations

A quantitative immunofluorescence method based on the covalent coupling of protein to sepharose beads

1974 • 61 citations

Localisation of the Gγ-, Aγ-, δ- and β-globin genes on the short arm of human chromosome 11

1979 • 61 citations

Chromosomal Localization of Human Haemoglobin Structural Genes

1972 • 59 citations

[27] Controlled partial hydrolysis of RNA

1967 • 55 citations

Specific detection of kinetoplast DNA in cytological preparations of trypanosomes by hybridization with complementary RNA

1973 • 46 citations

The structure of kinetoplast DNA

1975 • 43 citations

Binding of proteins to CNBr‐activated sepharose 4B

1974 • 42 citations

Chromosomal Localization of Human Haemoglobin Structural Genes: Techniques Queried

1973 • 41 citations

Cyanogen bromide activation of polysaccharides

1977 • 38 citations

The location of 5S (ribosomal) RNA genes in Drosophila hydei

1975 • 32 citations

[10] Modification of the 3′ terminus of tRNA by periodate oxidation and subsequent reaction with hydrazides

1979 • 27 citations

Repetitive DNA in Drosophila

1973 • 25 citations

RNA Hybridization to DNA Coupled with Cyanogen‐Bromide‐Activated Sephadex

1978 • 20 citations

Covalent attachment of fluorescent probes to the X-base of Escherichia coli phenylalanine transfer ribonucleic acid

1977 • 18 citations

In situ hybridization of iodinated ribosomal RNA to human chromosomes

1974 • 15 citations

Human Repetitious DNA

1974 • 14 citations

Micro-step-exclusion chromatography

1977 • 12 citations

The activity of two heat shock loci of Drosophila hydei in tissue culture cells and salivary gland cells as analyzed by in situ hybridization of complementary DNA

1979 • 11 citations

The products of the ?heat-shock? loci of Drosophila hydei

1978 • 8 citations