Nitric oxide-mediated, endothelium-dependent vasodilation is selectively attenuated in the postischemic extremity.

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1987 • 1,171 citations

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

1991 • 691 citations

Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.

1991 • 499 citations

Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat.

1990 • 471 citations

Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism

1971 • 457 citations

The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability.

1985 • 415 citations

Nitric oxide synthesized from L‐arginine regulates vascular tone in the coronary circulation of the rabbit

1989 • 279 citations

Neutrophil-mediated microvascular dysfunction in postischemic canine skeletal muscle. Role of granulocyte adherence.

1990 • 221 citations

Time course and mechanism of endothelial dysfunction in isolated ischemic- and hypoxic-perfused rat hearts

1990 • 204 citations

Ischemia-reperfusion impairs endothelium-dependent relaxation of coronary microvessels but does not affect large arteries.

1990 • 182 citations

Mechanisms and therapy of myocardial reperfusion injury.

1990 • 132 citations

Renal ischemia and reperfusion impair endothelium-dependent vascular relaxation

1989 • 94 citations

Responses of cerebral arteries after ischemia and reperfusion in cats

1988 • 89 citations

Endothelial cell dysfunction after ischemic arrest and reperfusion: A possible mechanism of myocardial injury during reflow

1991 • 76 citations

Acetylcholine-induced vasodilatation in rabbit hindlimb in vivo is not inhibited by analogues of L-arginine

1991 • 76 citations

Assessment and follow-up of pediatric survivors of sudden cardiac death.

1990 • 66 citations

Ischemia-reperfusion injury in isolated rat hindquarters

1990 • 62 citations

The temporal relationship between endothelial cell dysfunction and skeletal muscle damage after ischemia and reperfusion

1992 • 56 citations

Is adenosine 5'-triphosphate derangement or free-radical-mediated injury the major cause of ventricular dysfunction during reperfusion? Role of adenine nucleoside transport in myocardial reperfusion injury.

1990 • 46 citations

Xanthine oxidase: its role in the no-reflow phenomenon.

1992 • 41 citations

N omega-nitro-L-arginine selectively inhibits vasodilator responses to acetylcholine and bradykinin in cats

1991 • 41 citations

Time course and extent of recovery of endothelium-dependent contractions and relaxations after direct arterial injury

1991 • 39 citations

Nitric oxide requirement for vasomotor nerve‐induced vasodilation and modulation of resting blood flow in muscle microcirculation

1991 • 38 citations

Nitric Oxide Synthesis from l-Arginine Modulates Renal Vascular Resistance in Isolated Perfused and Intact Rat Kidneys

1991 • 34 citations

A clinically applicable method for long-term salvage of postischemic skeletal muscle

1991 • 30 citations

Acetylcholine vasodilation of resistance vessels in vivo may not entirely depend on newly synthesized nitric oxide

1991 • 29 citations

Vasodilator actions of acetylcholine, A23187 and bradykinin in the guinea‐pig isolated perfused heart are independent of prostacyclin

1988 • 25 citations

Endothelial Dysfunction in the Splanchnic Circulation Following Ischemia and Reperfusion

1991 • 25 citations

EDRF released from microvascular endothelial cells dilates arterioles in vivo

1991 • 17 citations

Leukocyte-Dependent and Leukocyte-Independent Mechanisms of Impairment of Endothelium-Mediated Vasodilation

1990 • 15 citations

Hemodynamic Effects of NG-Monomethyl-L-Arginine and NG-Nitro-L-Arginine Methyl Ester in Conscious, Unrestrained Rats

1991 • 11 citations