Behavioral Effects of Opiates: A Pharmacogenetic Analysis

Opiate Receptor: Demonstration in Nervous Tissue

1973 • 2,364 citations

Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines.

1953 • 1,702 citations

Psychopharmacology. A Review of Progress, 1957-1967

1969 • 844 citations

Regional Distribution of Opiate Receptor Binding in Monkey and Human Brain

1973 • 811 citations

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

1973 • 523 citations

Differences in Alcohol Preference among Inbred Strains of Mice

1959 • 453 citations

Genetic Aspects of Learning and Memory in Mice

1969 • 377 citations

On the central sites for the antinociceptive action of morphine and fentanyl

1970 • 265 citations

Factors Influencing Drug Metabolism

1962 • 258 citations

PHYSIOLOGICAL PHARMACOLOGY

1963 • 227 citations

DEVELOPMENT AND LOSS OF TOLERANCE TO MORPHINE IN THE RAT AFTER SINGLE AND MULTIPLE INJECTIONS.

1964 • 200 citations

Physiological Aspects of Tolerance and Physical Dependence

1963 • 196 citations

Genotype-dependent sensitivity and tolerance to morphine and heroin: Dissociation between opiate-induced running and analgesia in the mouse

1974 • 194 citations

DRUG‐INDUCED CHANGES IN BRAIN ACETYLCHOLINE

1962 • 187 citations

Biogenic amines and narcotic effects. I. Modification of morphine-induced analgesia and motor activity after alteration of cerebral amine levels.

1973 • 172 citations

Effects of narcotic analgesics upon the locomotor activity and brain catecholamine content of the mouse.

1971 • 149 citations

New Concepts in Neurotransmitter Regulation

1974 • 148 citations

Genetic experiments with animal learning: A critical review

1972 • 144 citations

Genetic Studies of Sleep in Mice

1972 • 126 citations

New Concepts in Neurotransmitter Regulation

1973 • 123 citations

Tolerance to opioid narcotics. I. Tolerance to the "running fit" caused by levorphanol in the mouse.

1969 • 122 citations

ACUTE TOLERANCE TO NARCOTIC ANALGESIC DRUGS IN RATS

1968 • 116 citations

Sites of action of morphine involved in the development of physical dependence in rats

1976 • 112 citations

Brain sites of precipitated abstinence in morphine-dependent rats.

1973 • 108 citations

Measurement of alcohol preference in genetic experiments.

1964 • 101 citations

Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration.

1973 • 93 citations

Effects of Morphine and its Antagonists on Release of Cerebral Cortical Acetylcholine

1970 • 92 citations

Correlation of Behavioural Differences in Three Strains of Mice with Differences in Brain Amines

1974 • 86 citations

Effects of narcotic analgesic agonists and antagonists on rat brain acetylcholine.

1973 • 80 citations

A genetic analysis of morphine-induced running and analgesia in the mouse

1975 • 77 citations

Genotype-dependent sensitivity to morphine: role of different opiate receptor populations

1980 • 73 citations

Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats

1974 • 73 citations

Comparative Study of Acetylcholinesterase and Choline Acetyltransferase Enzyme Activity in Brain of DBA and C57 Mice

1973 • 72 citations

ACTION OF NICOTINE ON SPONTANEOUS AND ACQUIRED BEHAVIOR IN RATS AND MICE*

1967 • 66 citations

The effect of p-chlorophenylalanine on opiate-induced running, analgesia, tolerance and physical dependence in mice.

1971 • 63 citations

Effect of Amphetamine, Nicotine and Hexamethonium on Performance of a Conditioned Response During Acquisition and Retention Trials

1970 • 57 citations

Behavioral Genetics

1971 • 56 citations

A comparison of the effects of d-amphetamine and morphine upon the locomotor activity of mice treated with drugs which alter brain catecholamine content.

1973 • 52 citations

Strain differences in the effects of chlorpromazine and chlordiazepoxide upon active and passive avoidance in mice

1970 • 51 citations

Effects of genotype on mouse behaviour

1966 • 51 citations

Acute tolerance to morphine following systemic and intracerebral injection in the rat

1966 • 49 citations

A simple method for producing tolerance to dihydromorphinone in mice.

1963 • 48 citations

Regional Brain Norepinephrine Turnover Rates in Four Strains of Mice

1971 • 47 citations

Species differences and the clinical trial of new drugs: A review

1966 • 46 citations

Some behavioral differences associated with relative size of hippocampus in the mouse.

1971 • 46 citations

Brain acetylcholine levels in rats with septal lesions

1971 • 45 citations

Genotype-dependent sensitivity to morphine: dopamine involvement in morphine-induced running in the mouse

1976 • 45 citations

Genetic analysis of susceptibility to morphine addiction in inbred mice.

1971 • 42 citations

DRUG TOXICITY AS A RESULT OF INTERFERENCE WITH PHYSIOLOGICAL CONTROL MECHANISMS

1965 • 40 citations

Modification of Precipitated Morphine and Methadone Abstinence in Mice by Acetylcholine Antagonists

1973 • 38 citations

Changes in acetylcholinesterase activity in hippocampus produced by septal lesions in the rat

1973 • 36 citations

Genotype-dependent effects of septal lesions on different types of learning in the mouse.

1973 • 35 citations

Effect of reserpine, alpha-methyl-p-tyrosine, p-chlorophenylalanine and pargyline on levorphanol-induced running activity in mice.

1969 • 35 citations

The effect of strychine on inhibition in Deiters' nucleus induced by GABA and glycine

1969 • 31 citations

Morphine-induced running and analgesia in two strains of mice following septal lesions or modification of brain amines

1975 • 30 citations

Effects of L- and D-amino acids on analgesia and locomotor activity of mice: their interaction with morphine

1980 • 29 citations

Strain differences in the analgesic response to morphine as measured on the hot plate.

1973 • 23 citations

Experience modifies morphine-induced behavioural excitation of mice

1974 • 23 citations

Variation in effects of chlorpromazine in three strains of mice

1966 • 21 citations

Effects of heroin, alone or in combination with other drugs, on the locomotor activity in two inbred strains of mice

1976 • 21 citations

Differences in reversal learning between two inbred mouse strains

1970 • 20 citations

Effects of morphine and pentobarbitone on acetylcholine synthesis by rat cerebral cortex

1970 • 20 citations

Acute morphine tolerance in new born and young rats

1973 • 18 citations

Genotype-dependent electroencephalographic, behavioral and analgesic correlates of morphine: An analysis in normal mice and in mice with septal lesions

1975 • 16 citations

Psychopharmacology — A biological approach

1976 • 15 citations

Genetic aspects of drug safety.

1966 • 11 citations

Serotoninergic neurotransmission and morphine activity.

1972 • 9 citations

Strain differences on the effects of chlordiazepoxide and chlorpromazine in avoidance behaviour of mice

1974 • 9 citations

The Narcotic Analgesics

1981 • 5 citations

Relation of Brain Serotonin to the Inhibition and Enhancement of Morphine Tolerance and Physical Dependence

1973 • 5 citations

Psychopharmacology : a biological approach

1975 • 4 citations