Evolutionary and Somatic Immunological Memory

The clonal selection theory of acquired immunity

1959 • 2,008 citations

The clonal selection theory of acquired immunity

1959 • 1,576 citations

Cell Selection by Antigen in the Immune Response

1969 • 594 citations

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

1984 • 534 citations

B–cell memory is short-lived in the absence of antigen

1988 • 430 citations

Stable Expression and Somatic Hypermutation of Antibody V Regions in B-Cell Developmental Pathways

1989 • 271 citations

Macromolecules and Behavior

1972 • 246 citations

Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses

1987 • 230 citations

THE CARRIAGE OF IMMUNOLOGICAL MEMORY BY SMALL LYMPHOCYTES IN THE RAT

1966 • 195 citations

Stepwise intraclonal maturation of antibody affinity through somatic hypermutation.

1988 • 160 citations

Germline antibody V regions as determinants of clonal persistence and malignant growth in the B cell compartment.

1988 • 139 citations

Macromolecules and behavior

1967 • 127 citations

SEQUENTIAL CHANGES IN THE RELATIVE AFFINITY OF ANTIBODIES SYNTHESIZED DURING THE IMMUNE RESPONSE

1967 • 122 citations

QUANTITATIVE STUDIES OF THE ADOPTIVE IMMUNOLOGICAL MEMORY IN MICE

1966 • 113 citations

Activation of memory and virgin B cell clones in hyperimmune animals

1987 • 90 citations

A study of avidity based on rabbit skin responses to diphtheria toxin-antitoxin mixtures.

1951 • 79 citations

INITIATION OF ANTIBODY RESPONSES BY DIFFERENT CLASSES OF LYMPHOCYTES

1972 • 76 citations

Factors affecting the propagation of a B Cell Clone forming antibody to the 2,4‐dinitrophenyl group

1972 • 56 citations

Beobachtungen über das Maserncontagium

1847 • 55 citations

Network regulation among T cells; Conclusions from limiting dilution experiments

1983 • 54 citations

The molecular evolution of the immune response: idiotope‐specific suppression indicates that B cells express germ‐line‐encoded V genes prior to antigenic stimulation

1986 • 53 citations

In vitro activation of murine antigen-specific memory B cells by a T-dependent antigen.

1986 • 51 citations

Amplification of B cell clones forming antibody to the 2,4‐dinitrophenyl group

1972 • 34 citations

Secondary antibody responses to thymus‐independent antigens. Decline and life‐span of memory

1988 • 22 citations

Growth and Selection of B Cells In Vivo

1989 • 10 citations