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The Mechanism of Action of Amantadine and Rimantadine Against Influenza Viruses

Data up to Jan 2025

Published1989
Citations32
References19

Total Citations Per Year

Abstract

References (19)

THE STRUCTURE AND FUNCTION OF THE HEMAGGLUTININ MEMBRANE GLYCOPROTEIN OF INFLUENZA VIRUS

1987 • 1,391 citations

The molecular basis of the specific anti-influenza action of amantadine.

1985 • 800 citations

Synthetic Amphiphilic Peptide Models for Protein Ion Channels

1988 • 593 citations

Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface

1985 • 579 citations

A Controlled Trial of Amantadine and Rimantadine in the Prophylaxis of Influenza a Infection

1982 • 501 citations

A view of acidic intracellular compartments.

1988 • 380 citations

Genetic basis of resistance to rimantadine emerging during treatment of influenza virus infection

1988 • 287 citations

Children With Influenza A Infection: Treatment With Rimantadine

1987 • 198 citations

Molecular basis of resistance of influenza A viruses to amantadine

1986 • 187 citations

Biologic Potential of Amantadine-Resistant Influenza A Virus in an Avian Model

1989 • 122 citations

Susceptibility of influenza A viruses to amantadine is influenced by the gene coding for M protein

1978 • 105 citations

The nicotinic acetylcholine receptor: Molecular architecture of a ligand-regulated ion channel

1987 • 101 citations

Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults

1986 • 80 citations

The Matrix Protein Gene Determines Amantadine-Sensitivity of Influenza Viruses

1979 • 68 citations

Chemotherapy and vaccination: a possible strategy for the control of highly virulent influenza virus

1985 • 64 citations

Protective efficacy of low-dose amantadine in adults challenged with wild-type influenza A virus

1987 • 58 citations

Amantadine-resistant and -sensitive Influenza A Strains and Recombinants

1979 • 55 citations

Uncoating of a Rimantadine-resistant Variant of Influenza Virus in the Presence of Rimantadine

1982 • 40 citations

Structure-activity relationships of amantadine. I. Interaction of the N-alkyl analogues with the ionic channels of the nicotinic acetylcholine receptor and electrically excitable membrane.

1982 • 30 citations

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