Nuclear Magnetic Resonance Approaches to Membrane Protein Structure

The Principles of Nuclear Magnetism

1961 • 14,411 citations

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution

1985 • 3,049 citations

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1990 • 2,969 citations

Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.

1987 • 2,216 citations

Atomic model of plant light-harvesting complex by electron crystallography

1994 • 1,907 citations

Rapid recording of 2D NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins

1989 • 1,395 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

Nuclear Resonance Absorption in Hydrated Crystals: Fine Structure of the Proton Line

1948 • 1,214 citations

A novel approach for sequential assignment of proton, carbon-13, and nitrogen-15 spectra of larger proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin

1990 • 836 citations

Molecular Architecture and Electrostatic Properties of a Bacterial Porin

1991 • 700 citations

Rotational resonance in solid state NMR

1988 • 611 citations

PEPTIDES FROM FROG SKIN

1990 • 577 citations

Antibacterial peptides: Key components needed in immunity

1991 • 570 citations

Rotational-echo double-resonance NMR

2011 • 554 citations

Defining Solution Conformations of Small Linear Peptides

1991 • 528 citations

Filamentous bacterial viruses

1969 • 454 citations

Biological Macromolecules and Assemblies

1987 • 400 citations

Determination of Three-Dimensional Structures of Proteins and Nucleic Acids in Solution by Nuclear Magnetic Resonance Spectroscop

1989 • 342 citations

Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance

1983 • 336 citations

The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study

1988 • 282 citations

[8] Solid state nuclear magnetic resonance of lipid bilayers

1981 • 279 citations

Physicochemical studies of the protein-lipid interactions in melittin-containing micelles

1979 • 279 citations

Distance geometry and related methods for protein structure determination from NMR data

1987 • 215 citations

Detection of prokaryotic signal peptidase in an Escherichia coli membrane fraction: endoproteolytic cleavage of nascent f1 pre-coat protein.

1978 • 209 citations

THE BACTERIAL PHOTOSYNTHETIC REACTION CENTER AS A MODEL FOR MEMBRANE PROTEINS

1989 • 204 citations

Determination of the nitrogen-15 and carbon-13 chemical shift tensors of L-[13C]alanyl-L-[15N]alanine from the dipole-coupled powder patterns

1987 • 187 citations

Orientations of amphipathic helical peptides in membrane bilayers determined by solid-state NMR spectroscopy

1991 • 186 citations

Filamentous bacterial viruses.

1969 • 185 citations

Protein structure by solid-state NMR spectroscopy

1987 • 184 citations

COMATOSE, a method for constrained refinement of macromolecular structure based on two-dimensional nuclear overhauser effect spectra

1988 • 184 citations

Two-dimensional 13C NMR of highly oriented polyethylene

1977 • 168 citations

Biological Macromolecules and Assemblies

1985 • 163 citations

Deuterium-labeled lipids as structural probes in liquid crystalline bilayers. Deuterium magnetic resonance study

1974 • 163 citations

High resolution nuclear magnetic resonance studies of the conformation and orientation of melittin bound to a lipid-water interface

1982 • 163 citations

NMR Studies of the Structure and Dynamics of Membrane-Bound Bacteriophage Pf1 coat protein

1991 • 158 citations

Rotation of Molecules and Nuclear Spin Relaxation

1978 • 136 citations

Developmental abnormalities in transgenic mice expressing a sialic acid-specific 9-O-acetylesterase

1991 • 130 citations

M2 delta, a candidate for the structure lining the ionic channel of the nicotinic cholinergic receptor.

1988 • 130 citations

Application of ³¹P NMR to model and biological membrane systems

1975 • 130 citations

Structure and assembly of filamentous bacterial viruses

1975 • 129 citations

Solid State NMR Studies of Protein Internal Dynamics

1984 • 122 citations

Three-dimensional structure of a cloning vector

1992 • 117 citations

Structure of melittin bound to perdeuterated dodecylphosphocholine micelles as studied by two-dimensional NMR and distance geometry calculations

1989 • 115 citations

The sampling properties of some distance geometry algorithms applied to unconstrained polypeptide chains: A study of 1830 independently computed conformations

1990 • 114 citations

NMR structural analysis of a membrane protein: bacteriorhodopsin peptide backbone orientation and motion

1985 • 112 citations

Molecular anatomy and molecular design of channel proteins

1990 • 104 citations

15N chemical shift and 15N-13C dipolar tensors for the peptide bond in [1-13C]glycyl[15N]glycine hydrochloride monohydrate

1984 • 91 citations

Flat-coil probe for NMR spectroscopy of oriented membrane samples

1991 • 90 citations

Helix formation and stability in a signal sequence

1989 • 86 citations

Use of fully deuterated micelles for conformational studies of membrane proteins by high resolution 1H nuclear magnetic resonance

1979 • 83 citations

Nuclear magnetic resonance investigation of the conformation of δ-haemolysin bound to dodecylphosphocholine micelles

1987 • 82 citations

Aggregation-related conformational change of the membrane-associated coat protein of bacteriophage M13

1989 • 80 citations

Surface dynamics of the integral membrane protein bacteriorhodopsin

1984 • 71 citations

The in situ determination of the 15N chemical-shift tensor orientation in a polypeptide

1989 • 70 citations

Membrane-Mediated Assembly of Filamentous Bacteriophage Pf1 Coat Protein

1991 • 63 citations

Dynamics of fd coat protein in lipid bilayers

1987 • 61 citations

[17]Protein dynamics by solid state nuclear magnetic resonance

1986 • 60 citations

Detection of 1H homonuclear NOE between amide sites in proteins with heteronuclear correlation spectroscopy

1989 • 60 citations

Nitrogen-15 spin exchange in a protein

1983 • 57 citations

High-Resolution Solid-State NMR of Proteins

1988 • 55 citations

Structure and dynamics of the Pf1 filamentous bacteriophage coat protein in micelles

1987 • 53 citations

[13] Solid-State nuclear magnetic resonance structural studies of proteins

1989 • 52 citations

Fluorotyrosine M13 coat protein: fluorine-19 nuclear magnetic resonance study of the motional properties of an integral membrane protein in phospholipid vesicles

1978 • 52 citations

Biotechnology: Bridging Research and Applications

1991 • 50 citations

Structural properties of fd coat protein in sodium dodecyl sulfate micelles

1980 • 49 citations

Carbon-13 spin exchange in amino acids and peptides

1984 • 48 citations

NMR: basic principles and progress

1972 • 47 citations

High resolution ¹H NMR study of the solution structure of the S4 segment of the sodium channel protein

1989 • 45 citations

A 1H NMR study of the solution conformation of the neuropeptide Galanin

1990 • 44 citations

Solid State NMR of Biological Systems

1982 • 43 citations

Mechanism of proton pumping in bacteriorhodopsin by solid-state NMR: the protonation state of tyrosine in the light-adapted and M states

1991 • 40 citations

Two-dimensional NMR study of the conformation of (34–65)bacterioopsin polypeptide in SDS micelles

1991 • 38 citations

Protein backbone dynamics by solid-state and solution 15N NMR spectroscopy

1987 • 37 citations

Hydrogen exchange kinetics in a membrane protein determined by nitrogen-15 NMR spectroscopy: use of the INEPT experiment to follow individual amides in detergent-solubilized M13 coat protein

1990 • 35 citations

ChemInform Abstract: PROTEIN STRUCTURE BY SOLID‐STATE NMR

1983 • 34 citations

The in situ aggregational and conformational state of the major coat protein of bacteriophage M13 in phospholipid bilayers mimicking the inner membrane of host Escherichia coli

1991 • 30 citations

Comparison of the dynamics of the membrane‐bound form of fd coat protein in micelles and in bilayers by solution and solid‐state nitrogen‐15 nuclear magnetic resonance spectroscopy

1988 • 26 citations

The M2δ transmembrane domain of the nicotinic cholinergic receptor forms ion channels in human erythrocyte membranes

1989 • 22 citations

Lipid-dependent Structural Changes of an Amphomorphic Membrane Protein

1982 • 22 citations

[41] Recent advances in the study of bacteriorhodopsin dynamic structure using high-field solid-state nuclear magnetic resonance spectroscopy

1982 • 19 citations

Sequence-specific resonance assignment and secondary structure of (1–71) bacterioopsin

1992 • 18 citations

Conformation and aggregation of M13 coat protein studied by molecular dynamics

1991 • 16 citations

Molecular dynamics simulation of Pf1 coat protein

1993 • 12 citations

NMR-Structural Studies of Membrane Bound Peptides and Proteins

1991 • 8 citations

Deleted Work

1955 • 0 citations