Multiple Organ Failure

ASSESSMENT OF COMA AND IMPAIRED CONSCIOUSNESS

1974 • 12,376 citations

ACUTE RESPIRATORY DISTRESS IN ADULTS

1967 • 4,096 citations

An Expanded Definition of the Adult Respiratory Distress Syndrome

1988 • 2,636 citations

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Prospective Trial of Supranormal Values of Survivors as Therapeutic Goals in High-Risk Surgical Patients

1988 • 1,808 citations

A Controlled Clinical Trial of High-Dose Methylprednisolone in the Treatment of Severe Sepsis and Septic Shock

1987 • 1,434 citations

Multiple-Organ Failure

1985 • 1,314 citations

Prognosis in Acute Organ-System Failure

1985 • 1,248 citations

Treatment of Gram-Negative Bacteremia and Shock with Human Antiserum to a MutantEscherichia coli

1982 • 1,062 citations

High-Dose Corticosteroids in Patients with the Adult Respiratory Distress Syndrome

1987 • 881 citations

Multiple Organ Failure

1999 • 820 citations

Adult Respiratory Distress Syndrome: Risk with Common Predispositions

1983 • 810 citations

Causes of Mortality in Patients With the Adult Respiratory Distress Syndrome

1986 • 798 citations

[Multiple organ failure syndrome].

1988 • 795 citations

Multiple System Organ Failure

1980 • 751 citations

Role of neutrophils in ischemia-reperfusion-induced microvascular injury

1987 • 704 citations

Endotoxin and lung injury.

1986 • 679 citations

State of the Art

1983 • 655 citations

Multiple Organ System Failure and Infection in Adult Respiratory Distress Syndrome

1983 • 654 citations

A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance.

1985 • 620 citations

The Effects of Vasodilation with Prostacyclin on Oxygen Delivery and Uptake in Critically Ill Patients

1987 • 559 citations

Adult Respiratory-Distress Syndrome

1982 • 554 citations

Cytokine appearance in human endotoxemia and primate bacteremia.

1988 • 528 citations

Oxygen delivery and uptake in dogs during anemic and hypoxic hypoxia

1977 • 474 citations

Physiology and Physiopathology of the Reticuloendothelial System

1970 • 412 citations

Endotoxin Promotes the Translocation of Bacteria From the Gut

1987 • 403 citations

PREVENTION OF GRAM-NEGATIVE SHOCK AND DEATH IN SURGICAL PATIENTS BY ANTIBODY TO ENDOTOXIN CORE GLYCOLIPID

1985 • 381 citations

Critical level of oxygen delivery in anesthetized man

1983 • 380 citations

Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis.

1987 • 348 citations

TRIPLE REGIMEN OF SELECTIVE DECONTAMINATION OF THE DIGESTIVE TRACT, SYSTEMIC CEFOTAXIME, AND MICROBIOLOGICAL SURVEILLANCE FOR PREVENTION OF ACQUIRED INFECTION IN INTENSIVE CARE

1988 • 319 citations

Fluid Balance and the Adult Respiratory Distress Syndrome^1–3

1987 • 269 citations

Acute in vivo effects of human recombinant tumor necrosis factor.

1987 • 256 citations

Intravascular coagulation associated with the adult respiratory distress syndrome

1976 • 254 citations

Incidence, site, and outcome of infections in patients with the adult respiratory distress syndrome.

1986 • 241 citations

Relationship between O2 Delivery and O2 Consumption in the Adult Respiratory Distress Syndrome

1983 • 219 citations

Neutrophils Kill Pulmonary Endothelial Cells by a Hydrogen-Peroxide-Dependent Pathway

1984 • 213 citations

A Prospective Study of Lung Water Measurements during Patient Management in an Intensive Care Unit

1987 • 198 citations

Monocyte and granulocyte-mediated tumor cell destruction. A role for the hydrogen peroxide-myeloperoxidase-chloride system.

1982 • 159 citations

Direct effects of E coli endotoxin on structure and permeability of pulmonary endothelial monolayers and the endothelial layer of intimal explants.

1986 • 149 citations

Multiple Organ Failure

1977 • 131 citations

Supply Dependency of Oxygen Uptake in ARDS: Myth or Reality?

1984 • 120 citations

Organ Interactions in the Adult Respiratory Distress Syndrome during Sepsis

1988 • 120 citations

Distribution of respiratory muscle and organ blood flow during endotoxic shock in dogs

1985 • 114 citations

Oxygen Transport in the Critically Ill

1987 • 104 citations

Regulation of tissue oxygen extraction is disturbed in adult respiratory distress syndrome.

1985 • 103 citations

Oxygen Delivery and Uptake by Peripheral Tissues: Physiology and Pathophysiology

1989 • 99 citations

Effect of end-stage liver failure on the incidence and resolution of the adult respiratory distress syndrome

1987 • 96 citations

Gastrointestinal Hemorrhage in Patients in a Respiratory Intensive Care Unit

1977 • 90 citations

Oxygen consumption and blood flow in resting mammalian skeletal muscle

1974 • 79 citations

Mechanisms of Multiple Nonpulmonary Organ Failure in ARDS

1989 • 75 citations

Renal failure in the respiratory intensive care unit

1979 • 72 citations

Assessment of Tissue Oxygenation

1986 • 70 citations

Alterations in regional blood flow during positive end- expiratory pressure ventilation

1987 • 66 citations

Lung Neutrophils in the Adult Respiratory Distress Syndrome

2015 • 65 citations

Pathophysiologic responses of the subhuman primate in experimental septic shock.

1975 • 61 citations

The influence of PEEP ventilation on organ blood flow and peripheral oxygen delivery

1982 • 55 citations

Regulation of tissue oxygen extraction is disturbed in adult respiratory distress syndrome

1986 • 46 citations

Severe microvascular injury induced by lysosomal releasates of human polymorphonuclear leukocytes. Increase in vasopermeability, hemorrhage, and microthrombosis due to degradation of subendothelial and perivascular matrices.

1985 • 45 citations

Neutrophil Accumulation and Structural Changes in Nonpulmonary Organs after Acute Lung Injury Induced by Phorbol Myristate Acetate

1989 • 43 citations

Relationships of Oxygen Uptake and Oxygen Delivery in Respiratory Failure Not Due to the Adult Respiratory Distress Syndrome

1988 • 43 citations

Interleukin-1-induced granulocytopenia and pulmonary leukostasis in rabbits

1987 • 40 citations

Monokine-induced acute lung injury in rabbits

1987 • 40 citations

Anatomic Arterial-venous Shunting in Endotoxic and Septic Shock in Dogs

1977 • 36 citations

Oxygen Delivery and Uptake in the Adult Respiratory Distress Syndrome

2015 • 34 citations

Oxygen Distribution and Utilization after Phorbol Myristate Acetate-induced Lung Injury

1988 • 23 citations

A morphologic study of live Escherichia coli organism shock in baboons

1979 • 20 citations

Bacterial translocation: Is it of clinical significance?

1990 • 17 citations

Leukotrienes C4 and D4 do not increase filtration coefficient of excised perfused guinea pig lungs

1987 • 13 citations

Multiple Systems Organ Failure

1990 • 7 citations

THE EFFECT OF RENAL AND RESPIRATORY FAILURE ON SURGICAL ICU MORTALITY

1979 • 6 citations