Physiology of IgA and IgA deficiency.

Immunoglobulin A (IgA): Molecular and Cellular Interactions Involved in IgA Biosynthesis and Immune Response

1987 • 956 citations

The structure and function of human IgA

1990 • 564 citations

Selective IgA deficiency: presentation of 30 cases and a review of the literature.

1971 • 515 citations

The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

1984 • 507 citations

Intracellular neutralization of virus by immunoglobulin A antibodies.

1992 • 438 citations

Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID)

2000 • 417 citations

TGF-β Receptor Controls B Cell Responsiveness and Induction of IgA In Vivo

2000 • 403 citations

Intravascular and Mucosal Immunoglobulin A: Two Separate but Related Systems of Immune Defense?

1987 • 372 citations

The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: a local defense function for IgA.

1991 • 346 citations

IgG Subclasses in Selective IgA Deficiency

1981 • 324 citations

THE NORMAL HUMAN INTESTINAL MUCOSA AS A MAJOR SOURCE OF PLASMA CELLS CONTAINING GAMMA-A-IMMUNOGLOBULIN.

1965 • 301 citations

ANAPHYLACTOID TRANSFUSION REACTIONS ASSOCIATED WITH ANTI-IgA

1968 • 282 citations

Cellular distribution, regulation, and biochemical nature of an Fc alpha receptor in humans.

1990 • 240 citations

Correlation of Milk Precipitins with IgA Deficiency

1969 • 209 citations

Targeted Deletion of the IgA Constant Region in Mice Leads to IgA Deficiency with Alterations in Expression of Other Ig Isotypes

1999 • 194 citations

IgA anaphylactic transfusion reactions

1995 • 194 citations

Differentiation Capacity of Cultured B Lymphocytes from Immunodeficient Patients

1973 • 190 citations

Selective IgA Deficiency in Blood Donors

1975 • 169 citations

Impaired Lung Function in Patients with IgA Deficiency and Low Levels of IgG2 or IgG3

1985 • 152 citations

Milk precipitins, circulating immune complexes, and IgA deficiency.

1978 • 150 citations

Susceptibility Locus for IgA Deficiency and Common Variable Immunodeficiency in the HLA-DR3, -B8, -A1 Haplotypes

1998 • 145 citations

Mucosal Immunity to Influenza Without IgA: An IgA Knockout Mouse Model

1999 • 141 citations

Selective IgA Deficiency in Japanese Blood Donors: Frequency and Statistical Analysis¹

1986 • 138 citations

Fine Mapping ofIGAD1in IgA Deficiency and Common Variable Immunodeficiency: Identification and Characterization of Haplotypes Shared by Affected Members of 101 Multiple-Case Families

2000 • 129 citations

Genetic Linkage of IgA Deficiency to the Major Histocompatibility Complex: Evidence for Allele Segregation Distortion, Parent-of-Origin Penetrance Differences, and the Role of Anti-IgA Antibodies in Disease Predisposition

1999 • 126 citations

Bovine Antigens and the Formation of Circulating Immune Complexes in Selective Immunoglobulin A Deficiency

1979 • 124 citations

Immature I_GA B Cells in I_GA-Deficient Patients

1981 • 120 citations

Syndromes associated with deletion of the long arm of chromosome 18[del(18q)]

1979 • 115 citations

Partial IgA-deficiency with increased Th2-type cytokines in TGF-beta 1 knockout mice.

1999 • 107 citations

Celiac Sprue and Immunodeficiency States: A 25-Year Review

1997 • 100 citations

Deficiency of IL-5 receptor alpha-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues.

1999 • 99 citations

IgA determinants on B-lymphocytes in patients with deficiency of circulating IgA.

1972 • 97 citations

IV. How epithelial transport of IgA antibodies relates to host defense

1998 • 91 citations

Family studies of IgA deficiency

1985 • 89 citations

Immunoglobulin levels in saliva in individuals with selective IgA deficiency: Compensatory IgM secretion and its correlation with HLA and susceptibility to infections

1989 • 86 citations

Immunoglobulin A deficiency: genetic studies

1982 • 80 citations

Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM: studies of diffusion, binding to the human polymeric Ig receptor, and epithelial transcytosis.

1997 • 70 citations

[Ataxiatelangiectasis. (7 personal cases)].

1961 • 68 citations

The Covalent Linkage of Secretory Component to IgA. Structure of sIgA

1993 • 66 citations

Anti-IgA antibodies in selective IgA deficiency and in primary immunodeficient patients treated with γ-globulin

1988 • 62 citations

TRANSFER OF IgA DEFICIENCY TO A BONE-MARROW-GRAFTED PATIENT WITH APLASTIC ANAEMIA

1985 • 58 citations

Inadequacy of musocal IgM antibodies in selective IgA deficiency: Excretion of attenuated polio viruses is prolonged

1988 • 53 citations

Immunohistochemical Findings in the Intestine of IgA-Deficient Persons

1988 • 53 citations

Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA‐B8, SC01, DR3] conserved extended haplotype

2000 • 50 citations

Dimerization of the Polymeric Immunoglobulin Receptor Controls Its Transcytotic Trafficking

1998 • 48 citations

Eczema and atopy in early childhood: low IgA plasma cell counts in the jejunal mucosa.

1981 • 45 citations

Anti-IgA Antibodies in Pregnancy

1985 • 38 citations

SELECTIVE IgA DEFICIENCY

1975 • 37 citations

Discordance between IgA Switching at the DNA Level and IgA Expression at the mRNA Level in IgA-Deficient Patients

1999 • 37 citations

Anti-IgA-mediated transfusion reactions in Canada.

1984 • 36 citations

IgA synthesis by peripheral blood mononuclear cells from normal and selectively IgA deficient subjects.

1979 • 33 citations

Reduced Serum Level of Transforming Growth Factor-β in Patients with IgA Deficiency

1995 • 31 citations

Immunochemical Characterization of IgM in Human Intestinal Fluids

1977 • 29 citations

Selective IgA deficiency with 18q+ and 18q-- karyotypic anomalies.

1980 • 25 citations

B‐Cell Activation in Duodenal Mucosa after Oral Cholera Vaccination in IgA Deficient Subjects with or without IgG Subclass Deficiency

1993 • 22 citations

Study of colostrum of a patient with selective IgA deficiency.

1985 • 18 citations

IL-10-driven immunoglobulin production by B lymphocytes from IgA-deficient individuals correlates to infection proneness

1996 • 18 citations

IgA deficiency.

1991 • 16 citations

A putative susceptibility locus on chromosome 18 is not a major contributor to human selective IgA deficiency: evidence from meiotic mapping of 83 multiple-case families.

1999 • 15 citations

Low incidence of selective IgA deficiency in normal Malaysians.

1979 • 14 citations

The Coexistence of IgA Deficiency and 21‐Hydroxylase Deficiency Marked by Specific MHC Supratypes

1985 • 13 citations

IgA deficiency.

1991 • 6 citations

Clinical, immunologic and epidemiologic characteristics of canine selective IgA deficiency.

1987 • 5 citations

Analysis of IgG subclass production in cell cultures from IgA deficient patients and in normal controls as a function of age.

1986 • 4 citations