Lipoarabinomannan from Mycobacterium tuberculosis induces the production of tumour necrosis factor from human and murine macrophages.

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Structure and antigenicity of the phosphorylated lipopolysaccharide antigens from the leprosy and tubercle bacilli.

1986 • 325 citations

Lipid A: Chemical Structure and Biological Activity

1973 • 288 citations

Synergy between tumor necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice.

1988 • 260 citations

Action of recombinant human interleukin 6, interleukin 1β and tumor necrosis factor α on the mRNA induction of acute‐phase proteins

1988 • 254 citations

Studies of enterobacterial lipopolysaccharides; effects of heat and chemicals on erythrocyte-modifying, antigenic, toxic and pyrogenic properties.

1956 • 233 citations

Mycobacterial lipoarabinomannan inhibits gamma interferon-mediated activation of macrophages

1988 • 224 citations

The role of gamma-interferon, vitamin D3 metabolites and tumour necrosis factor in the pathogenesis of tuberculosis.

1987 • 215 citations

Malarial parasites induce TNF production by macrophages.

1988 • 177 citations

The inhibitory effects of mycobacterial lipoarabinomannan and polysaccharides upon polyclonal and monoclonal human T cell proliferation.

1988 • 145 citations

Definition of species specific and cross-reactive antigenic determinants of Mycobacterium leprae using monoclonal antibodies.

1983 • 136 citations

Immunological activity of a 38-kilodalton protein purified from Mycobacterium tuberculosis

1986 • 135 citations

T lymphocytes respond to solid-phase antigen: a novel approach to the molecular analysis of cellular immunity.

1986 • 98 citations

Leprosy and the Leprosy Bacillus: Recent Developments in Characterization of Antigens and Immunology of the Disease

1987 • 96 citations

Preparation and Characterization of Monoclonal Antibodies Directed Against Antigenic Determinants of Recombinant Human Tumour Necrosis Factor (rTNF)

1987 • 63 citations

Role of activated macrophages in the immunopathology of tuberculosis

1988 • 62 citations

Most Mycobacterium leprae carbohydrate-reactive monoclonal antibodies are directed to lipoarabinomannan

1987 • 62 citations

Non-reactive Tuberculosis

1954 • 60 citations

Lipoarabinomannan and lipid-free arabinomannan antigens of Mycobacterium paratuberculosis

1987 • 56 citations

Demonstration of soluble Plasmodium falciparum antigens reactive with Limulus amoebocyte lysate and polymyxin B

1988 • 36 citations

Mechanism of the anti-tumour effect of glucans and fructosans: a comparison with C. parvum

1977 • 17 citations