The effects of endotoxaemia on protein metabolism in skeletal muscle and liver of fed and fasted rats

Mammalian Protein Metabolism

1969 • 1,828 citations

A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine

1980 • 983 citations

Stimulation of Muscle Protein Degradation and Prostaglandin E₂Release by Leukocytic Pyrogen (Interleukin-1)

1983 • 689 citations

Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or Trauma

1983 • 469 citations

The relative importance of muscle protein synthesis and breakdown in the regulation of muscle mass

1976 • 346 citations

The effect of insulin infusion and food intake on muscle protein synthesis in postabsorptive rats

1983 • 270 citations

Magnitude of the host nutritional responses to infection

1977 • 262 citations

Intracellular Protein Catabolism

1996 • 259 citations

Nitrogen metabolism in man.

1981 • 253 citations

Role of Insulin in the Regulation of Protein Synthesis

1980 • 234 citations

Time course of the effect of catabolic doses of corticosterone on protein turnover in rat skeletal muscle and liver

1983 • 200 citations

The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines

1984 • 166 citations

Urinary excretion of 3-methylhistidine: An assessment of muscle protein catabolism in adult normal subjects and during malnutrition, sepsis, and skeletal trauma

1981 • 148 citations

Multifunctional control of amino acids of deprivation-induced proteolysis in liver. Role of leucine.

1982 • 139 citations

Changes in body balances of nitrogen and other key nutrients: description and underlying mechanisms

1977 • 135 citations

A Protein from Polymorphonuclear Leukocytes (LEM) Which Affects the Rate of Hepatic Amino Acid Transport and Synthesis of Acute-Phase Globulins

1975 • 128 citations

Differential tissue sensitivity to elevated endogenous insulin levels during experimental peritonitis in rats

1974 • 119 citations

The Combined Effects of Infection and Malnutrition on Protein Metabolism in Children

1983 • 115 citations

Protein metabolism in skeletal muscle: the effect of feeding and fasting on muscle RNA, free amino acids and plasma insulin concentrations

1974 • 102 citations

Depressed protein synthesis is the dominant characteristic of muscle wasting and cachexia

1983 • 99 citations

Inhibitors of prostaglandin synthesis or cathepsin B prevent muscle wasting due to sepsis in the rat.

1984 • 93 citations

Systemic response to thermal injury in rats. Accelerated protein degradation and altered glucose utilization in muscle.

1984 • 88 citations

Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin

1983 • 86 citations

The role of insulin, corticosterone and other factors in the acute recovery of muscle protein synthesis on refeeding food-deprived rats

1983 • 84 citations

Thyroid hormones and muscle protein turnover. The effect of thyroid-hormone deficiency and replacement in thryoidectomized and hypophysectomized rats

1981 • 81 citations

Control of protein degradation in muscle by prostaglandins, Ca2+, and leukocytic pyrogen (interleukin 1).

1984 • 78 citations

Dose response of protein turnover in rat skeletal muscle to triiodothyronine treatment

1983 • 74 citations

Changes in Protein Synthesis Due to an Inflammatory Challenge

1984 • 71 citations

Comparison of different techniques for estimating rates of protein synthesis in vivo in healthy and bacteraemic rats

1985 • 64 citations

Leukocyte endogenous mediator alters protein dynamics in rats

1983 • 61 citations

The possible involvement of prostaglandin F2α in the stimulation of muscle protein synthesis by insulin

1983 • 54 citations

Muscle protein synthesis in the streptozotocin-diabetic rat. A possible role for corticosterone in the insensitivity to insulin infusion in vivo

1982 • 53 citations

The effect of intermittent changes in tension on protein and collagen synthesis in isolated rabbit muscles

1981 • 52 citations

The effect of indomethacin on the stimulation of protein synthesis by insulin in young post-absorptive rats

1985 • 49 citations

Insulin Receptors in Acute Infection: A Study of Factors Conferring Insulin Resistance*

1984 • 45 citations

Nitrogen Metabolism and Protein Synthesis During Pneumococcal Sepsis in Rats

1972 • 42 citations

Changes in prostaglandin release associated with inhibition of muscle protein synthesis by dexamethasone

1984 • 39 citations

Effect of infection on protein and nucleic acid synthesis in mammalian organs and tissues.

1966 • 38 citations

Stimulation of protein synthesis and breakdown by vaccination.

1980 • 38 citations

Increased muscle glucose uptake and lactate release after endotoxin administration

1980 • 37 citations

Limited effects of prostaglandin inhibitors in Escherichia coli sepsis.

1985 • 28 citations

Effect of Infection on Skeletal Muscle Ribosomes in Rats Fed Adequate or Low Protein

1968 • 25 citations

Role of thyroid, insulin and corticosteroid hormones in the physiological regulation of proteolysis in muscle.

1985 • 20 citations

Prostaglandin E2 and muscle protein turnover inPseudomonas aeruginosa sepsis

1985 • 18 citations

Serum and tissue T3 levels in endotoxin shock in the rat

1983 • 9 citations

Muscle Prostaglandin Production in the Rat

1985 • 6 citations