Changes in body balances of nitrogen and other key nutrients: description and underlying mechanisms

Interactions of Nutrition and Infection

1969 • 1,332 citations

Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm.

1975 • 916 citations

Iron and Susceptibility to Infectious Disease

1974 • 576 citations

Impaired Leukocyte Function in Patients with Poorly Controlled Diabetes

1974 • 553 citations

Fever and Survival

1975 • 476 citations

Binding of Drugs to Serum Albumin

1976 • 410 citations

Acute-Phase Reactants

1974 • 398 citations

The plasma proteins : structure, function, and genetic control

1975 • 388 citations

The value and duration of defence reactions of the skin to the primary lodgement of bacteria.

1957 • 378 citations

STUDIES ON HUMAN PLASMA α2-MACROGLOBULIN-ENZYME INTERACTIONS

1973 • 362 citations

The role of ceruloplasmin in iron metabolism

1970 • 360 citations

Effect of ketone infusions on amino acid and nitrogen metabolism in man.

1975 • 331 citations

Bacterial and Mycotic Infections of Man

1965 • 330 citations

The plasma proteins: Structure, function, and genetic control

1976 • 312 citations

Zinc Therapy of Acrodermatitis Enteropathica

1975 • 309 citations

Immunologic responses in malnourished children

1975 • 272 citations

Neutrophil Actin Dysfunction and Abnormal Neutrophil Behavior

1974 • 266 citations

Competition for zinc among serum albumin and amino acids

1972 • 235 citations

Nonsuppressability of gluconeogenesis by glucose in septic patients

1976 • 226 citations

Metal Binding in Medicine

1961 • 210 citations

Effects of Glucagon on Amino Acid Transport and Utilization in the Perfused Rat Liver

1969 • 202 citations

Metabolic Effects of Intracellular Infections in Man

1967 • 200 citations

The immune response in iron-deficient children: Impaired cellular defense mechanisms with altered humoral components

1975 • 199 citations

Abnormal Pancreatic Alpha-Cell Function in Bacterial Infections

1973 • 190 citations

Key role of various individual amino acids in host response to infection

1977 • 186 citations

Binding of Drugs to Serum Albumin

1976 • 176 citations

Zinc and Wound Healing

1970 • 162 citations

Isolation of a zinc α2-macroglobulin from human serum

1970 • 157 citations

Effect of Glucagon: Insulin Ratios on Hepatic Metabolism

1974 • 153 citations

The metabolic events of starvation

1976 • 152 citations

Protease Inhibitors in Plasma

1975 • 150 citations

The significance and mechanism of an increased serum phenylalanine-tyrosine ratio during infection

1976 • 147 citations

The Effect of Leukocytic Endogenous Mediator (LEM) on the Tissue Distribution of Zinc and Iron

1972 • 138 citations

Decreased RNA Polymerase Activity in Mammalian Zinc Deficiency

1972 • 132 citations

Stimulation by insulin of rat liver β-hydroxy-β-methylglutaryl coenzyme A reductase and cholesterol-synthesizing activities

1973 • 131 citations

A Protein from Polymorphonuclear Leukocytes (LEM) Which Affects the Rate of Hepatic Amino Acid Transport and Synthesis of Acute-Phase Globulins

1975 • 128 citations

Uptake of proteinase-α-macroglobulin complexes by macrophages☆

1975 • 127 citations

ZINC REQUIREMENT FOR DNA REPLICATION IN STIMULATED HUMAN LYMPHOCYTES

1973 • 122 citations

Differential tissue sensitivity to elevated endogenous insulin levels during experimental peritonitis in rats

1974 • 119 citations

Purification and Partial Characterization of PAS-Positive Inclusion Bodies from the Liver in Alpha₁-Antitrypsin Deficiency

1975 • 119 citations

Multiple biological activities of a partially purified leukocytic endogenous mediator

1973 • 99 citations

Induced and spontaneous diabetes mellitus and suppression of cell-mediated immunologic responses. Granuloma formation, delayed dermal reactivity and allograft rejection.

1976 • 97 citations

Characterization of the Endogenous Mediator(s) of Serum Zinc and Iron Depression During Infection and Other Stresses

1971 • 97 citations

The Phagocytic cell in host resistance

1975 • 97 citations

Phagocytosis and immunity. The central role of phagocytosis in immune reactions.

1966 • 95 citations

Evidence for ceruloplasmin as a copper transport protein

1975 • 95 citations

The role of the liver in the production of fever and in pyrogenic tolerance.

1968 • 89 citations

Effects of anti-insulin serum, insulin, and glucose on output of triglycerides and on ketogenesis by the perfused rat liver.

1976 • 89 citations

Synthesis and secretion of alpha2-macroglobulin by cultured human fibroblasts.

1976 • 88 citations

Urinary amino acid excretion during experimentally induced sandfly fever in man

1975 • 84 citations

THE HEALING OF GASTRIC ULCERS BY ZINC SULPHATE

1975 • 81 citations

Pathogenesis and immunology of experimental gonococcal infection: role of iron in virulence

1975 • 81 citations

Studies on the metabolism of the serum proteins and lipids in a patient with analbuminemia

1964 • 75 citations

An Endogenous Mediator of Depression of Amino Acids and Trace Metals in Serum during Typhoid Fever

1972 • 75 citations

Influence of acute tissue injury on zinc metabolism in man.

1972 • 74 citations

PROTEIN METABOLISM IN TYPHOID FEVER

1909 • 74 citations

The effect of bacterial infections on ketone concentrations in rat liver and blood and on free fatty acid concentrations in rat blood

1976 • 73 citations

Effect of interaction between insulin and glucagon on glucose turnover and FFA concentration in normal and depancreatized dogs

1974 • 71 citations

Inhibition of lethality in endotoxin-challenged mice treated with zinc chloride

1976 • 70 citations

Effect of Zinc on the Viability and Phagocytic Capacity of Peritoneal Macrophages

1973 • 67 citations

Effects of ketone bodies on amino acid metabolism in isolated rat diaphragm

1976 • 66 citations

The Effect of Leukocytic Endogenous Mediator (LEM) on Serum Copper and Ceruloplasmin Concentrations in the Rat

1972 • 66 citations

α₁,‐ANTITRYPSIN AND α₂–MACROGLOBULIN. INTERACTIONS WITH HUMAN NEUTROPHIL COLLAGENASE AND ELASTASE

1975 • 66 citations

NITROGEN METABOLISM IN ACUTE INFECTIONS 1

1945 • 64 citations

The effect of live attenuated Venezuelan equine encephalomyelitis virus vaccine on serum iron, zinc, and copper concentrations in man.

1970 • 62 citations

Total Parenteral Nutrition: Premises and Promises

1976 • 61 citations

The interaction of collagen with glycoprotein

1976 • 58 citations

On the inhibition of elastase by serum. Some distinguishing properties of α1-antitrypsin and α2-macroglobulin

1975 • 58 citations

Neutrophils: Their Role in the Formation of a Tick Feeding Lesion

1970 • 57 citations

The Thyroxine-Binding Properties of Rat and Rabbit Serum Proteins

1976 • 55 citations

Effect of Leukocytic Endogenous Mediator on Plasma Fibrinogen and Haptoglobin

1974 • 53 citations

Amino acid and zinc movement in relation to protein synthesis early in inflammation

1973 • 53 citations

Detection of a leukocytic endogenous mediator-like mediator of serum amino acid and zinc depression during various infectious illnesses

1975 • 52 citations

Zinc Deficiency and Incorporation of 14C-labeled Methionine into Tissue Proteins in Rats

1969 • 52 citations

ZINC DEFICIENCY AND CELLULAR IMMUNE DEFICIENCY IN ACRODERMATITIS ENTEROPATHICA

1975 • 49 citations

Overnutrition on resistance of dogs to distemper virus.

1966 • 47 citations

Intracerebroventricular Administration of Leukocytic Endogenous Mediators (LEM) in the Rat

1976 • 46 citations

Nitrogen Metabolism and Protein Synthesis During Pneumococcal Sepsis in Rats

1972 • 42 citations

Mediator of Hepatic Amino Acid Flux in Infected Rats

1972 • 42 citations

Infection-induced hyperglucagonemia and altered hepatic response to glucagon in the rat

1974 • 41 citations

Sequential changes in the concentration of specific serum proteins during typhoid fever infection in man.

1976 • 40 citations

Tissue Amino Acid Flux After Exposure of Rats to Diplococcus pneumoniae

1971 • 39 citations

Thymus factors in immunity

1975 • 39 citations

Effect of infection on protein and nucleic acid synthesis in mammalian organs and tissues.

1966 • 38 citations

The effect of zinc deficiency on wound healing

1974 • 37 citations

Further evidence that leukocytic endogenous mediator (LEM) is not endotoxin

1974 • 36 citations

The effect of concentration of glucagon on output of triglyceride, ketone bodies, glucose, and urea by the liver

1973 • 35 citations

Induced metabolic sequelae of tularemia in the rat: correlation with tissue damage

1975 • 35 citations

Preliminary studies on the synthesis of alpha2-macroglobulin by human lymphocytes in vitro.

1974 • 34 citations

Phagocytosis and immunity

1966 • 33 citations

Fat metabolism in normal and abnormal states

1977 • 32 citations

Effects of pneumococcal infection on rat liver microsomal enzymes and lipogenesis by isolated hepatocytes

1977 • 32 citations

Haptoglobin Synthesis. I. In Vivo Studies of the Production of Haptoglobin, Fibrinogen, and γ-Globulin by the Canine Liver*

1965 • 31 citations

Induction of ceruloplasmin synthesis by copper

1970 • 31 citations

The Inhibition of Proteinases by Human α₁‐Antitrypsin

1974 • 31 citations

Haptoglobin synthesis. II. Cellular localization studies.

1966 • 30 citations

CRC handbook of nutrition and food

2002 • 29 citations

Association of macrophage-activation factor from a human cultured lymphoid cell line with albumin and α2-macroglobulin

1976 • 29 citations

Effect of infection on human protein metabolism.

1966 • 28 citations

Reaction of haptoglobin with hemoglobin covalently cross-linked between the alpha beta dimers.

1976 • 28 citations

Induced and spontaneous diabetes mellitus and suppression of cell-mediated immunologic responses.

1976 • 27 citations

Effects of Acute Infection on Cholesterogenesis in the Rhesus Monkey

1971 • 25 citations

Differentiation between endogenous pyrogen and leukocytic endogenous mediator

1977 • 25 citations

Serum Proteins in Health and Disease.

1968 • 25 citations

The influence of α-1-antitrypsin on plasmin, urokinase and hageman factor cofactor

1974 • 25 citations

Effect of Infection on Skeletal Muscle Ribosomes in Rats Fed Adequate or Low Protein

1968 • 25 citations

The metabolism of α2-macroglobulin in mildly burned patients

1973 • 23 citations

SERUM PROTEINS IN HEALTH AND DISEASE

1968 • 21 citations

Effects of infection with Diplococcus pneumoniae on synthesis of ribonucleic acids in rat liver

1973 • 21 citations

Effect of Glucagon and of Insulin on Serum Free Fatty Acids in Normal and Depancreatized Dogs

1969 • 19 citations

Serum glycoproteins in protein-calorie deficiency disease

1971 • 18 citations

Involvement of Leukocytic Proteases in Emphysema and Antitrypsin Deficiency

1973 • 17 citations

Turnover rate of orosomucoid in the dog with sterile abscess

1972 • 16 citations

Comparison of the effects of zinc deprivation and actinomycin D on ribonucleic acid synthesis by stimulated lymphocytes

1975 • 15 citations

The role of alpha1-antitrypsin and alpha-macroglobulins in the uptake of proteinase by rabbit alveolar macrophages.

1975 • 13 citations

Distribution and metabolism of phenylalanine and tyrosine during tularaemia in the rat (Short Communication)

1974 • 13 citations

THE TURNOVER RATE OF OROSOMUCOID IN BURNED PATIENTS

1970 • 13 citations

Protein Synthesis in Zinc Deficient Rats during Tularemia

1976 • 12 citations

Effects of infection on selected clinical and biochemical parameters in dogs.

1970 • 12 citations

Bactericidal activities of phagocytes in health and disease

1974 • 12 citations

Alterations in Plasma Copper, Zinc, Amino Acids, and Seromucoid during Rocky Mountain Spotted Fever in Guinea Pigs

1976 • 12 citations

A carbohydrate inhibitor of cathepsin B activity associated with haptoglobin

1974 • 11 citations

Characterization and pathophysiology of serum glycoprotein alterations in malaria.

1972 • 11 citations

Changes in Plasma Protein-Bound Carbohydrates and Glycoprotein Patterns During Infection, Inflammation and Starvation

1973 • 10 citations

Possible relation of prostaglandins to PMN-derived mediators of host metabolic responses to inflammation

1977 • 8 citations

PROTEINS IN HEALTH AND DISEASE

1948 • 8 citations

CHANGES IN SERUM-ALPHA2- MACROGLOBULIN LEVELS IN CHILDREN AFTER MAJOR BONE SURGERY

1972 • 8 citations

Serum Macroglobulin Stimulation of the Proliferation and Differentiation of Granulocytic Precursors

1975 • 7 citations

Alterations in hepatic chromatin template availability during infection

1975 • 7 citations

The effect of human alpha 2-macroglobulin on the restoration of humoral responsiveness in x-irradiated mice.

1975 • 6 citations

Binding and Inhibition of Cathepsin B1 by α2-Macroglobulin

1973 • 4 citations

Physicochemical and Kinetic Studies of the Interaction between Histamine and Ceruloplasmin as an Allosteric Enzyme

1972 • 4 citations

A proposed role for alpha1 macroglobulin in the promotion of alpha1 acute-phase globulin synthesis by the perfused rat liver.

1975 • 3 citations

Alteration of Template Activity of Chromatin from Livers of Pneumococcus-Infected Mice

1971 • 2 citations

Effect of serum alpha1-antitrypsin on the proteolytic activity of purulent sputum.

1973 • 1 citations

Deleted Work

1955 • 0 citations