Modification of Dopamine Receptor-Mediated Processes After Chronic Ethanol Intoxication: A Possible Mechanism

The membrane actions of anesthetics and tranquilizers.

1972 • 2,194 citations

Tyrosine Hydroxylase

1964 • 2,038 citations

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the “dopamine receptor”

1972 • 1,022 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 811 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

ADENYL CYCLASE AS AN ADRENERGIC RECEPTOR*

1967 • 682 citations

Membrane receptors for hormones and neurotransmitters.

1976 • 573 citations

Dopamine Receptors in the Brain

1975 • 528 citations

Drug Tolerance in Biomembranes: A Spin Label Study of the Effects of Ethanol

1977 • 511 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 487 citations

Adaptation of membrane lipids to alcohols

1976 • 483 citations

Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

1976 • 480 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 469 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Drug‐Induced Changes in the Release of ³H‐Monoamines from Field Stimulated Rat Brain Slices

1971 • 453 citations

Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

1974 • 450 citations

Evidence for a receptor-mediated feedback control of striatal tyrosine hydroxylase activity

1972 • 421 citations

Cyclic nucleotides and nervous system function.

1977 • 411 citations

Excitation-mediating and inhibition-mediating dopamine-receptors: A new concept towards a better understanding of electrophysiological, biochemical, pharmacological, functional and clinical data

1976 • 368 citations

Protein activator of cyclic 3′:5′-nucleotide phosphodiesterase of bovine or rat brain also activates its adenylate cyclase

1975 • 361 citations

Activation of pigeon erythrocyte membrane adenylate cyclase by guanylnucleotide analogues and separation of a nucleotide binding protein.

1975 • 337 citations

A method for the determination of 3,4-dihydroxyphenylalanine (DOPA) in brain

1972 • 273 citations

The Action of Neuroleptic Drugs on Dopamine-Stimulated Adenosine Cyclic 3',5'-Monophosphate Production in Rat Neostriatum and Limbic Forebrain

1974 • 240 citations

ALTERATIONS IN THE TURNOVER OF BRAIN NOREPINEPHRINE AND DOPAMINE IN ALCOHOL‐DEPENDENT RATS

1974 • 231 citations

Regulatory Properties of Soluble and Particulate Rat Brain Tyrosine Hydroxylase

1972 • 230 citations

Body temperature in mice: a quantitative measure of alcohol tolerance and physical dependence.

1976 • 228 citations

Dopamine receptor binding in the corpus striatum of mammalian brain.

1975 • 221 citations

Histamine-sensitive adenylate cyclase in mammalian brain

1976 • 218 citations

Dopaminergic neurons: drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow.

1974 • 208 citations

CHARACTERIZATION OF A DOPAMINE‐SENSITIVE ADENYLATE CYCLASE IN THE RAT CAUDATE NUCLEUS

1975 • 199 citations

Stimulatory and Inhibitory Effects of Guanyl Nucleotides on Fat Cell Adenylate Cyclase

1973 • 198 citations

Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.

1975 • 179 citations

Adenylate Cyclase in Islets of Langerhans

1973 • 178 citations

Synaptosomal membrane lipids of mice during continuous exposure to ethanol

1977 • 169 citations

Oxytocin-sensitive Adenylate Cyclase in Frog Bladder Epithelial Cells

1972 • 164 citations

Restoration of Norepinephrine Responsiveness of Solubilized Myocardial Adenylate Cyclase by Phosphatidylinositol

1971 • 161 citations

Alcohol and opiates : neurochemical and behavioral mechanisms

1977 • 157 citations

The ß-adrenergic receptor and adenylate cyclase

1976 • 148 citations

Stereospecificity of interaction of neuroleptic drugs with neurotransmitters and correlation with clinical potency

1976 • 124 citations

Uncoupling of Catecholamine Activation of Pigeon Erythrocyte Membrane Adenylate Cyclase by Filipin

1974 • 124 citations

Restoration of glucagon responsiveness of solubilized myocardial adenyl cyclase by phosphatidylserine

1971 • 123 citations

The Effects of Nucleotides on the Expression of β-Adrenergic Adenylate Cyclase Activity in Membranes from Turkey Erythrocytes

1974 • 118 citations

Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.

1976 • 116 citations

Development of functional dependence on ethanol in dopaminergic systems.

1979 • 113 citations

Hypothermic effect of apomorphine in the mouse

1972 • 105 citations

Binding of 5′-Guanylyl-Imidodiphosphate to Turkey Erythrocyte Membranes and Effects on β-Adrenergic-activated Adenylate Cyclase

1974 • 103 citations

Cholesterol modulates the effects of membrane perturbers in phospholipid vesicles and biomembranes

1978 • 101 citations

Adenylate cyclase-coupled beta adrenergic receptors effect of membrane lipid-perturbing agents on receptor binding and enzyme stimulation by catecholamines.

1976 • 101 citations

Supersensitivity and Dependence

1968 • 100 citations

Role of GTP in epinephrine and glucagon activation of adenyl cyclase of liver plasma membrane

1972 • 94 citations

Reduction of striatal dopamine release during an ethanol withdrawal syndrome

1977 • 89 citations

Participation of an endogenous Ca++-blinding protein activator in the development of drug-induced supersensitivity of striatal dopamine receptors.

1977 • 88 citations

EFFECTS OF ETHANOL ON SEROTONIN METABOLISM IN BRAIN

1974 • 85 citations

Alterations in dopamine receptor sensitivity by chronic ethanol treatment

1977 • 82 citations

On the functional role of pre- and postsynaptic catecholamine receptors in brain.

1975 • 79 citations

Adenylate‐Cyclase Activity of Rat‐Liver Plasma Membranes

1973 • 76 citations

Regulation of dopamine stimulation of striatal adenylate cyclase by an endogenous Ca++ -binding protein.

1976 • 73 citations

Agonist-antagonist interaction on dopamine receptors in brain, as reflected in the rates of tyrosine and tryptophan hydroxylation

1977 • 71 citations

Dopamine receptor function after chronic ingestion of ethanol

1978 • 70 citations

Biochemical regulation and physiological significance of cyclic nucleotides in the nervous system.

1977 • 67 citations

XIX. Enzyme expansion theory of drug tolerance and physical dependence.

1968 • 67 citations

Noradrenergic involvement in the acute effects of ethanol.

1975 • 64 citations

Dopaminergic neurons—Alteration in the sensitivity of tyrosine hydroxylase to inhibition by endogenous dopamine after cessation of impulse flow

1976 • 61 citations

ALTERATIONS IN RECEPTORS CONTROLLING DOPAMINE SYNTHESIS AFTER CHRONIC ETHANOL INGESTION

1978 • 60 citations

Effects of acute and chronic ethanol administration and withdrawal on adenosine 3':5'-monophosphate and guanosine 3':5'-monophosphate levels in the rat brain.

1977 • 60 citations

The role of phosphatidylserine in the hormonal control of adenylate cyclase of rat liver plasma membranes

1972 • 60 citations

Release of the phophodiesterase activator by cyclic AMP-dependent ATP:protein phosphotransferase from subcellular fractions of rat brain

1977 • 53 citations

Catecholamine synthesis in rat brain after axotomy: Interaction between apomorphine and haloperidol

1977 • 53 citations

Rat anterior pituitary adenyl cyclase activity: GTP requirement of prostaglandin E1 and E2 and synthetic luteinising hormone-releasing hormone activation

1973 • 47 citations

Receptors and acceptors: a necessary distinction in hormone binding studies.

1974 • 46 citations

Suppression of ethanol withdrawal by dopamine

1976 • 45 citations

Chemical and immunological characterization of specific glycoproteins from Trypanosoma equiperdum variants

1977 • 44 citations

Catecholamine stimulated myocardial adenylate cyclase: Effects of phospholipase digestion and the role of membrane lipids

1975 • 41 citations

The role of guanyl nucleotides in the expression on of catecholamine-responsive adenylate cyclase during maturation of the rat reticulocyte.

1977 • 38 citations

Biochemical aspects of alcoholism

1976 • 35 citations

Uncoupled β‐adrenergic receptors and adenylate cyclase can be recoupled by a GTP‐dependent cytosolic factor

1977 • 31 citations

The regulation of the kinetic state of striatal tyrosine hydroxylase and the role of postsynaptic dopamine receptors

1975 • 31 citations

Irreversible stimulation of adenylate cyclase activity of fat cell membranes by phosphoramidate and phosphonate analogs of GTP

1975 • 30 citations

NEUROCHEMICAL ASPECTS OF ETHANOL DEPENDENCE**This work was supported by U.S. Public Health Service Grants NS-12759 and AA-2696 and a Campus Research Board Grant from the University of Illinois. B.T. is a Schweppe Foundation Fellow.

1977 • 27 citations

Epinephrine stimulation of fat cell adenylate cyclase: Regulation by guanosine-5′-triphosphate and magnesium ion

1974 • 27 citations

DOPAMINE‐SENSITIVE ADENYLATE CYCLASE FROM THE RAT CAUDATE NUCLEUS: REGULATION BY GUANYL NUCLEOTIDES AND THE INTERACTION OF MAGNESIUM AND MAGNESIUM ATP¹

1978 • 25 citations

Inhibition by ethanol of noradrenaline output from peripheral sympathetic nerves: Possible interaction of ethanol with neuronal receptors

1976 • 25 citations

Effects of short-chain alcohols on adenylate cyclase in plasma membranes of rat adipocytes

1978 • 16 citations

Characterization of dopamine binding sites in standard preparations of brain synaptic membranes

1977 • 7 citations

Stimulation of rat striatal tyrosine hydroxylase by phospholipids and adenosine-3',5'-monophosphate.

1976 • 4 citations

EFFECT OF APOMORPHINE AND ITS N‐PROPYL HOMOLOGUE ON ETHANOL WITHDRAWAL HEAD TWITCHES IN MICE

1977 • 2 citations

[Linear- and Areal-analytical results of the karyometric studies on monolayer cultures and the influence of actinomycin (author's transl)].

1976 • 1 citations