Stereospecificity of interaction of neuroleptic drugs with neurotransmitters and correlation with clinical potency

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Muscarinic Cholinergic Binding in Rat Brain

1974 • 1,214 citations

Antipsychotic Drugs: Direct Correlation Between Clinical Potency and Presynaptic Action on Dopamine Neurons

1975 • 874 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

Properties of γ-aminobutyric acid (GABA) receptor binding in rat brain synaptic membrane fractions

1975 • 637 citations

Dopamine Receptors in the Brain

1975 • 528 citations

Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

1974 • 450 citations

Dopamine receptor binding: Differentiation of agonist and antagonist states with 3H-dopamine and 3H-haloperidol

1975 • 390 citations

Strychnine Binding Associated with Glycine Receptors of the Central Nervous System

1973 • 388 citations

Studies of the uptake of3H-GABA and [3H]glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography

1972 • 371 citations

Psychotropic Drugs and Related Compounds.

1967 • 279 citations

Current Developments in Psychopharmacology

1981 • 275 citations

Phenothiazines and structurally related drugs

1975 • 274 citations

Direct identification and characterisation of β-adrenergic receptors in rat brain

1975 • 246 citations

Autoradiographic identification of cerebral and cerebellar cortical neurons accumulating labeled gamma-aminobutyric acid (3H-GABA)

1972 • 244 citations

Current Developments in Psychopharmacology

1978 • 242 citations

Dopamine receptor binding in the corpus striatum of mammalian brain.

1975 • 221 citations

Neurotransmitter Receptors in the Brain: Biochemical Identification

1976 • 186 citations

Stereospecific binding ofd-lysergic acid diethylamide (LSD) to brain membranes: Relationship to serotonin receptors

1975 • 166 citations

Amino Acid Neurotransmitter Candidates: Sodium-Dependent High-Affinity Uptake by Unique Synaptosomal Fractions

1972 • 144 citations

The Comparative Pharmacology of Flupenthixol and some Reference Neuroleptics

1973 • 133 citations

Phenothiazines and structurally related drugs

1974 • 104 citations

Butyrophenone influences on the opiate receptor

1976 • 94 citations

Inhibition of the turnover of the brain dopamine after treatment with the gammaaminobutyrate: 2-oxyglutarate transaminase inhibitor aminooxyacetic acid

1974 • 65 citations

Effect of butaclamol and its enantiomers upon striatal homovanillic acid and adenyl cyclase of olfactory tubercle in rats

1975 • 59 citations

Neuroleptic agents of the benzocycloheptapyridoisoquinoline series. 1. Syntheses and stereochemical and structural requirements for activity of butaclamol and related compounds

1975 • 47 citations