Evaluation of adjuvants that enhance the effectiveness of antisense oligodeoxynucleotides.

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Small-volume extrusion apparatus for preparation of large, unilamellar vesicles

1991 • 1,461 citations

Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.

1994 • 1,306 citations

Biomembranes: molecular structure and function

1989 • 1,257 citations

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

1993 • 1,186 citations

Investigation of the bicinchoninic acid protein assay: Identification of the groups responsible for color formation

1988 • 751 citations

The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.

1994 • 668 citations

Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides.

1992 • 609 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action

1994 • 496 citations

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

1992 • 483 citations

Intracellular distribution of microinjected antisense oligonucleotides.

1991 • 362 citations

Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA

1990 • 297 citations

Rapid chemosensitivity testing of human lung tumor cells using the MTT assay

1986 • 289 citations

Antisense oligonucleotide strategies in neuropharmacology

1994 • 265 citations

Intracellular disposition and metabolism of fluorescently-labled unmodified and modified oligouncleotides microijjected into mammalian cells

1993 • 239 citations

Cellular uptake and intracellular fate of antisense oligonucleotides

1992 • 199 citations

Mechansism of cellular uptake of modified oligodeoxynucleotides containing methylphosphonate linkages

1991 • 174 citations

Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells

1993 • 172 citations

Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake

1990 • 160 citations

Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents

1979 • 123 citations

[42] Receptor-mediated transport of DNA into eukaryotic cells

1993 • 115 citations

pH Sensitization of Phospholipid Vesicles via Complexation with Synthetic Poly(carboxylic acid)s^a,b

1985 • 76 citations

The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole.

1987 • 74 citations

Cationic lipid-mediated transfection of liver cels in primary culture

1992 • 63 citations

Targeted delivery of antisense oligonucleotides by molecular conjugates

1992 • 53 citations

Synthesis and enhancing effect of dodecyl 2-(N,N-dimethylamino)propionate on the transepidermal delivery of indomethacin, clonidine, and hydrocortisone.

1993 • 40 citations

Lipid Membrane Permeability of 2′-Modified Derivatives of Phosphorothioate Oligonucleotides

1994 • 23 citations

Hyperinducible human metallothionein promoter with a low level basal activity

1994 • 14 citations