Protocols to establish genotype-phenotype correlations in Down syndrome.

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

1985 • 1,125 citations

Simultaneous fluorescent staining of R bands and specific heterochromatic regions (DA-DAPI bands) in human chromosomes

1980 • 468 citations

Growth Charts for Children With Down Syndrome: 1 Month to 18 Years of Age

1988 • 432 citations

Classification: Purposes, Principles, Progress, Prospects

1974 • 388 citations

Down's Syndrome and Alzheimer's disease: a review

1986 • 316 citations

Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome.

1989 • 261 citations

Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype.

1990 • 241 citations

Molecular genetic approach to the characterization of the ?Down syndrome region? of chromosome 21

1989 • 195 citations

Down's syndrome

1984 • 191 citations

Atlantoaxial Instability in Individuals With Down Syndrome: Epidemiologic, Radiographic, and Clinical Studies

1987 • 189 citations

Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions.

1990 • 187 citations

Characteristics of Children with Phonologic Disorders of Unknown Origin

1986 • 147 citations

The Amyloid β Protein Gene Is Not Duplicated in Brains from Patients with Alzheimer's Disease

1987 • 139 citations

The consequences of chromosome imbalance

2005 • 134 citations

Genetic linkage map of human chromosome 21

1988 • 125 citations

New Chromosome Techniques

1977 • 112 citations

In situ hybridization banding of human chromosomes with Alu-PCR products: A simultaneous karyotype for gene mapping studies

1991 • 104 citations

Down's Syndrome, Aging, and Alzheimer's Disease: A Clinical Review*

1982 • 96 citations

Neuropsychological correlates of information-processing by children with Down syndrome.

1985 • 95 citations

A genetic linkage map of 27 markers on human chromosome 21

1991 • 79 citations

The ITPA and Down's syndrome: an exploratory study.

1965 • 68 citations

Serial quantitative CT analysis of brain morphometrics in adult Down's syndrome at different ages

1989 • 62 citations

Report of the committee on the genetic constitution of chromosomes 20 and 21

1988 • 61 citations

Atlantoaxial instability in Down syndrome: Roentgenographic, neurologic, and somatosensory evoked potential studies

1987 • 54 citations

Down syndrome critical region around D21S55 on proximal 21q22.3

2005 • 49 citations

Cerebral metabolic pattern in young adult Down's syndrome subjects: altered intercorrelations between regional rates of glucose utilization

1990 • 49 citations

Dementia in Down's syndrome

1988 • 43 citations

Report of the committee on the genetic constitution of chromosome 21

1990 • 37 citations

Quantitative CT analysis of brain morphometry in adult Down's syndrome at different ages

1987 • 32 citations

Dichotic verbal processing in Down's syndrome children having qualitatively different speech and language skills.

1977 • 31 citations

Auditory P300 response in the assessment of Alzheimer's disease in Down's syndrome: a 2‐year follow‐up study

1988 • 30 citations

Evaluation of dermal patterns in Down's syndrome by predictive discrimination

1971 • 28 citations

THE DEVELOPMENT OF LANGUAGE ABILITIES IN MONGOLS: A CORRELATIONAL STUDY

1977 • 26 citations

Evaluation of dermal patterns in Down's syndrome by predictive discrimination. I. Preliminary analysis based on frequencies of patterns.

1971 • 25 citations

Auditory brainstem responses in young adults with Down syndrome.

1987 • 24 citations

Formal analysis of dysmorphism: Objective methods of syndrome definition

1983 • 23 citations

Slot blot method for the quantification of DNA sequences and mapping of chromosome rearrangements: application to chromosome 21.

1990 • 18 citations

Auditory Brainstem Responses

2015 • 17 citations

The relationship between cluster and liquid simplification and sentence length, age, and IQ in Down's syndrome children

1989 • 8 citations

Trisomy 9 (pter → q1 to q3): the phenotype as an objective aid to karyotypic interpretation

1984 • 4 citations