Pi-class glutathione-S-transferase-positive hepatocytes in aging B6C3F1 mice undergo apoptosis induced by dietary restriction.

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Apoptosis: The Biochemistry and Molecular Biology of Programmed Cell Death*

1993 • 1,005 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

1986 • 791 citations

Characterization and expression of a cDNA encoding the human androgen receptor.

1989 • 483 citations

Lifespan and Incidence of Cancer and Other Diseases in Selected Long-Lived Inbred Mice and Their F1 Hybrids2

1973 • 170 citations

Single GST-P positive liver cells — putative initiated. hepatocytes

1987 • 170 citations

An immunohistochemical study of pi class glutathione S-transferase expression in normal human tissue.

1990 • 157 citations

Multiple regulatory elements and phorbol 12-O-tetradecanoate 13-acetate responsiveness of the rat placental glutathione transferase gene.

1988 • 154 citations

Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene

1989 • 154 citations

Nuclear Factor κ B Functions as a Negative Regulator for the Rat Androgen Receptor Gene and NF- κ B Activity Increases during the Age-dependent Desensitization of the Liver

1995 • 148 citations

Human placental form of glutathione S-transferase (GST-pi) as a new immunohistochemical marker for human colonic carcinoma.

1986 • 133 citations

Rates of apoptosis and proliferation vary with caloric intake and may influence incidence of spontaneous hepatoma in C57BL/6 x C3H F1 mice.

1994 • 131 citations

Caloric restriction and 7,12-dimethylbenz(a)anthracene-induced mammary tumor growth in rats: alterations in circulating insulin, insulin-like growth factors I and II, and epidermal growth factor.

1989 • 116 citations

Transient induction of single GST-P positive hepatocytes by DEN

1989 • 113 citations

Developmental and hormonal regulation of the major form of hepatic glutathione S-transferase in male mice

1986 • 106 citations

Cell proliferation and apoptosis in normal liver and preneoplastic foci.

1993 • 90 citations

Age-related changes in the intrinsic rate of apoptosis in livers of diet-restricted and ad libitum-fed B6C3F1 mice.

1995 • 86 citations

Age-Related Neoplasia in a Lifetime Study of Ad Libitum-Fed and Food-Restricted B6C3F1 Mice

1995 • 82 citations

A novel regulatory element associated with age-dependent expression of the rat androgen receptor gene.

1993 • 77 citations

Short-Term Starvation Decreases POMC mRNA but Does Not Alter GnRH mRNA in the Brain of Adult Male Rats

1992 • 77 citations

Androgen Receptor Messenger Ribonucleic Acid (mRNA) in the Rat Liver: Changes in mRNA Levels during Maturation, Aging, and Calorie Restriction*

1991 • 77 citations

The Role of Calories and Caloric Restriction in Carcinogenesis

1991 • 62 citations

Mechanisms of Caloric Restriction Affecting Aging and Disease^a

1994 • 61 citations

Effect of food restriction on 24-h serum and pineal melatonin content in male rats

1987 • 55 citations

Strain dependent effects of sex hormones on hepatocarcinogenesis in mice

1996 • 49 citations

Elevated levels of C-jun and c-fos transcripts in the aged rat liver

1991 • 35 citations

Focal and non-focal hepatic expression of placental glutathione S-transferase in carcinogen-treated rats

1994 • 34 citations

c-Jun expression in single cells and preneoplastic foci induced by diethylnitrosamine in B6C3F1 mice: comparison with the expression of pi-class glutathione S-transferase

1994 • 26 citations

Sex-dependent expression of class pi glutathione S-transferase during chemical hepatocarcinogenesis in B6C3F1 mice

1993 • 25 citations

Naturally-occurring age-dependent glutathione S-transferase π immunoreactive hepatocytes in aging female F344 rat liver as potential promotable targets for non-genotoxic carcinogens

1990 • 24 citations

Caloric restriction perturbs the pituitary-ovarian axis and inhibits mouse mammary tumor virus production in a high-spontaneous-mammary-tumor-incidence mouse strain (C3H/SHN)

1989 • 21 citations

Focal impairment of growth in hepatocellular neoplasms of C57BL/6 mice: a possible explanation for the strain's resistance to hepatocarcinogenesis.

1989 • 19 citations

Cell proliferation and carcinogenesis models: general principles with illustrations from the rodent liver system.

1993 • 15 citations