Cloning and Expression of a Human 5-HT1D Receptor

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

1986 • 1,255 citations

[71] Use of eukaryotic expression technology in the functional analysis of cloned genes

1987 • 834 citations

Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor

1988 • 691 citations

The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor

1988 • 594 citations

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 509 citations

Adenylate cyclase assay.

1979 • 485 citations

Characterization of a novel 3H-5-hydroxytryptamine binding site subtype in bovine brain membranes

1987 • 406 citations

Structure and functional expression of cloned rat serotonin 5HT-2 receptor.

1988 • 381 citations

Species differences in the pharmacology of terminal 5-HT autoreceptors in mammalian brain

1989 • 354 citations

GR43175, a selective agonist for the 5‐HT₁‐like receptor in dog isolated saphenous vein

1988 • 305 citations

The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.

1990 • 280 citations

Peripheral neural serotonin receptors: identification and characterization with specific antagonists and agonists.

1986 • 202 citations

cDNA cloning of a serotonin 5-HT1C receptor by electrophysiological assays of mRNA-injected Xenopus oocytes.

1987 • 201 citations

Molecular pharmacology of 5-HT1D recognition sites: Radioligand binding studies in human, pig and calf brain membranes

1988 • 177 citations

Detection of a Novel Serotonin Receptor Subtype (5‐HT_1E) in Human Brain: Interaction with a GTP‐Binding Protein

1989 • 176 citations

A comparison of 5‐hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists

1985 • 136 citations

5-Hydroxytryptamine (5-HT)-induced endothelium-dependent relaxation of pig coronary arteries is mediated by 5-HT receptors similar to the 5-HT1D receptor subtype.

1990 • 134 citations

The 5-hydroxytryptamine 5-HT1D receptor subtype is negatively coupled to adenylate cyclase in calf substantia nigra

1988 • 126 citations

5.HT1 receptors in the vertebrate brain

1989 • 126 citations

Visualization of a novel serotonin recognition site (5-HT1D) in the human brain by autoradiography

1988 • 105 citations

Cardiovascular Pharmacology of 5-Hydroxytryptamine

1990 • 100 citations

The pharmacological properties of the presynaptic serotonin autoreceptor in the pig brain cortex conform to the 5-HT1D receptor subtype

1989 • 97 citations

5-HT1D receptors in guinea-pig and pigeon brain

1989 • 79 citations

[3H]-DOB(4-bromo-2,5-dimethoxyphenylisopropylamine) and [3H] ketanserin label two affinity states of the cloned human 5-hydroxytryptamine2 receptor.

1990 • 74 citations

Characterization and localization of a peripheral neural 5- hydroxytryptamine receptor subtype (5-HT1P) with a selective agonist, 3H-5-hydroxyindalpine

1988 • 70 citations

5‐HT_1D binding sites in porcine brain can be sub‐divided by GR43175

1989 • 59 citations

Further characterization of the 5‐HT receptor mediating vascular relaxation and elevation of cyclic AMP in porcine isolated vena cava

1989 • 58 citations

Comparison of the response to 5-carboxamidotryptamine and serotonin in isolated human, monkey and dog coronary arteries.

1990 • 52 citations

Serotonin 5‐HT_1D Receptors in Human Prefrontal Cortex and Caudate: Interaction with a GTP Binding Protein

1988 • 48 citations

Characterization of an Adenylate Cyclase‐Linked Serotonin (5‐HT₁) Receptor in a Neuroblastoma × Brain Explant Hybrid Cell Line (NCB‐20)

1983 • 47 citations

A rational approach to identifying a fundamentally new drug for the treatment of migraine

1990 • 47 citations

The relationship between agonist states of the M1 muscarinic receptor and the hydrolysis of inositol lipids in transfected murine fibroblast cells (B82) expressing different receptor densities.

1989 • 33 citations

Characterization of an endothelial 5-hydroxytryptamine (5-HT) receptor mediating relaxation of the porcine coronary artery

1989 • 30 citations

Sumatriptan (GR43175) inhibits cyclic‐AMP accumulation in dog isolated saphenous vein

1990 • 29 citations

GR 43175: A preferential 5‐HT_1D agent in monkey and human brains as shown by autoradiography

1989 • 24 citations

Characterization of a [3H]-5-hydroxytryptamine binding site in rabbit caudate nucleus that differs from the 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D subtypes

1989 • 24 citations

Cloning and Expression of a Human 5-HT1D Receptor

1991 • 20 citations

Postsynaptic localization and up-regulation of serotonin 5-HT1D receptors in rat brain

1989 • 15 citations

Partial agonistic activity of GR43175 at the inhibitory prejunctional 5‐HT₁‐like receptor in rat kidney

1989 • 12 citations