Tissue Factor Encryption/de-encryption Is not Altered in the Absence of the Cytoplasmic Domain

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor

1999 • 316 citations

A Role for Tissue Factor in Cell Adhesion and Migration Mediated by Interaction with Actin-binding Protein 280

1998 • 313 citations

Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation.

1995 • 303 citations

Factor VII binding to tissue factor in reconstituted phospholipid vesicles: induction of cooperativity by phosphatidylserine

1986 • 259 citations

Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis.

1998 • 243 citations

Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line.

1989 • 232 citations

Multiple Regression and the Analysis of Variance and Covariance

1986 • 219 citations

Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway.

1996 • 212 citations

Expression of tissue factor procoagulant activity: regulation by cytosolic calcium.

1990 • 212 citations

Association of tissue factor activity with the surface of cultured cells.

1975 • 182 citations

Tissue Factor and Factor VIIa Receptor/Ligand Interactions Induce Proinflammatory Effects in Macrophages

1999 • 178 citations

Binding of human factor VII and VIIa to monocytes.

1982 • 176 citations

Binding of Human Factor VIIa to Tissue Factor Induces Cytosolic Ca2+ Signals in J82 Cells, Transfected COS-1 Cells, Madin-Darby Canine Kidney Cells and in Human Endothelial Cells Induced to Synthesize Tissue Factor

1995 • 175 citations

Signal Transduction via the Mitogen-activated Protein Kinase Pathway Induced by Binding of Coagulation Factor VIIa to Tissue Factor

1998 • 151 citations

Tissue factor in microvesicles shed from U87MG human glioblastoma cells induces coagulation, platelet aggregation, and thrombogenesis

1984 • 149 citations

Mechanism of Tissue Factor Activation on HL-60 Cells

1997 • 142 citations

Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces.

1992 • 139 citations

Role of Tissue Factor in Metastasis: Functions of the Cytoplasmic and Extracellular Domains of the Molecule

1999 • 129 citations

The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism.

1992 • 125 citations

Tissue factor de-encryption: ionophore treatment induces changes in tissue factor activity by phosphatidylserine-dependent and -independent mechanisms.

1999 • 113 citations

An inhibitory monoclonal antibody against human tissue factor

1987 • 107 citations

Cooperation Between VEGF and TNF-α Is Necessary for Exposure of Active Tissue Factor on the Surface of Human Endothelial Cells

1999 • 106 citations

Human Brain Pericytes Differentially Regulate Expression of Procoagulant Enzyme Complexes Comprising the Extrinsic Pathway of Blood Coagulation

1997 • 104 citations

Factor VIIa-induced p44/42 Mitogen-activated Protein Kinase Activation Requires the Proteolytic Activity of Factor VIIa and Is Independent of the Tissue Factor Cytoplasmic Domain

1999 • 104 citations

The assembly of blood clotting complexes on membranes

1987 • 91 citations

Lipid association, but not the transmembrane domain, is required for tissue factor activity. Substitution of the transmembrane domain with a phosphatidylinositol anchor.

1991 • 89 citations

A new model to describe extrinsic protein binding to phospholipid membranes of varying composition: application to human coagulation proteins

1989 • 87 citations

[18] Purification of human coagulation factors II, IX, and X using sulfated dextran beads

1981 • 74 citations

Localization of Tissue Factor in Actin-Filament-Rich Membrane Areas of Epithelial Cells

1999 • 65 citations

Association of smooth muscle cell tissue factor with caveolae

1996 • 63 citations

Fibroblast tissue factor: calcium and ionophore induce shape changes, release of membrane vesicles, and redistribution of tissue factor antigen in addition to increased procoagulant activity

1994 • 55 citations

Studies of the Mechanism for Enhanced Cell Surface Factor VIIa/Tissue Factor Activation of Factor X on Fibroblast Monolayers after Their Exposure to N-Ethylmaleimide

1994 • 50 citations

Tissue factor activity in hela cells measured with a continuous chromogenic assay and elisa reader

1986 • 45 citations

Tissue Factor Cytoplasmic Domain Peptide Is Multiply Phosphorylated in Vitro

1997 • 43 citations

Opposite sorting of tissue factor in human umbilical vein endothelial cells and Madin-Darby canine kidney epithelial cells

1996 • 32 citations

Manifestation of cryptic fibroblast tissue factor occurs at detergent concentrations which dissolve the plasma membrane

1996 • 31 citations

Computerized analysis of enzyme cascade reactions using continuous rate data obtained with an ELISA reader

1985 • 28 citations

Discordant Expression of Tissue Factor and Its Activity in Polarized Epithelial Cells. Asymmetry in Anionic Phospholipid Availability as a Possible Explanation

1999 • 20 citations

Tissue factor antigen and activity are not expressed on the surface of intact cells isolated from an acute promyelocytic leukemia patient

1990 • 15 citations

Fibroblasts restrict tissue factor from vesicles which form in response to low concentrations of detergent

1996 • 8 citations

Immunofluorescent studies of tissue factor on U87MG cells: evidence for non-uniform distribution

1993 • 7 citations

Monoclonal antibodies against the C-terminal peptide of human tissue factor for studies of the cytoplasmic domain

1992 • 3 citations