Human Brain Pericytes Differentially Regulate Expression of Procoagulant Enzyme Complexes Comprising the Extrinsic Pathway of Blood Coagulation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis.

1989 • 1,199 citations

Bone morphogenetic protein expression in human atherosclerotic lesions.

1993 • 1,014 citations

How do the polyene macrolide antibiotics affect the cellular membrane properties?

1986 • 746 citations

Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane

1989 • 597 citations

Microvascular pericytes contain muscle and nonmuscle actins.

1985 • 399 citations

Complement proteins C5b-9 induce vesiculation of the endothelial plasma membrane and expose catalytic surface for assembly of the prothrombinase enzyme complex.

1990 • 342 citations

Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase

1990 • 290 citations

Factor VII binding to tissue factor in reconstituted phospholipid vesicles: induction of cooperativity by phosphatidylserine

1986 • 259 citations

Activation of human factor IX (Christmas factor).

1978 • 258 citations

The Vascular Endothelium

1993 • 240 citations

Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line.

1989 • 232 citations

Defibrination after Brain-Tissue Destruction

1974 • 229 citations

Expression of tissue factor procoagulant activity: regulation by cytosolic calcium.

1990 • 212 citations

Cell Culture Techniques in Heart and Vessel Research

1990 • 179 citations

Tissue factor in microvesicles shed from U87MG human glioblastoma cells induces coagulation, platelet aggregation, and thrombogenesis

1984 • 149 citations

Role of the clotting system in cell-mediated hypersensitivity. II. Kinetics of fibrinogen/fibrin accumulation and vascular permeability changes in tuberculin and cutaneous basophil hypersensitivity reactions.

1975 • 147 citations

Pericytes derived from the retinal microvasculature undergo calcification in vitro

1990 • 147 citations

Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation

1979 • 140 citations

Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces.

1992 • 139 citations

Disseminated intravascular coagulation associated with massive brain injury

1973 • 132 citations

Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine

1988 • 126 citations

The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism.

1992 • 125 citations

Deficiency of factor Xa-factor Va binding sites on the platelets of a patient with a bleeding disorder

1979 • 120 citations

Exposure of endogenous phosphatidylserine at the outer surface of stimulated platelets is reversed by restoration of aminophospholipid translocase activity

1989 • 102 citations

Molecular cloning of effector cell protease receptor-1, a novel cell surface receptor for the protease factor Xa.

1994 • 96 citations

Role of the Clotting System in Cell-Mediated Hypersensitivity

1975 • 91 citations

Effector Cell Protease Receptor-1, a Platelet Activation-dependent Membrane Protein, Regulates Prothrombinase-catalyzed Thrombin Generation

1997 • 87 citations

Cooperative interaction between factor VII and cell surface-expressed tissue factor.

1987 • 72 citations

Protease Nexin-1 and Thrombin: Injury-related Processes in the Brain

1993 • 68 citations

Translocation of spin-labeled phospholipids through plasma membrane during thrombin- and ionophore A23187-induced platelet activation

1993 • 66 citations

Redetermination of the rate-limiting step in the activation of factor IX by factor XIa and by factor VIIa/tissue factor. Explanation for different electrophoretic radioactivity profiles obtained on activation of 3H- and 125I-labeled factor IX

1983 • 61 citations

Fibroblast tissue factor: calcium and ionophore induce shape changes, release of membrane vesicles, and redistribution of tissue factor antigen in addition to increased procoagulant activity

1994 • 55 citations

Intact platelet membranes, not platelet-released microvesicles, support the procoagulant activity of adherent platelets.

1993 • 51 citations

Functional features of lymphocytes recovered from a human renal allograft

1973 • 51 citations

Studies of the Mechanism for Enhanced Cell Surface Factor VIIa/Tissue Factor Activation of Factor X on Fibroblast Monolayers after Their Exposure to N-Ethylmaleimide

1994 • 50 citations

α-Thrombin Stimulates Urokinase Production and DNA Synthesis in Cultured Human Cerebral Microvascular Endothelial Cells

1995 • 50 citations

Sequential receptor cascade for coagulation proteins on monocytes

1989 • 46 citations

Estimation of cellular DNA content in cell lysates suitable for RNA isolation

1990 • 44 citations

Development of Procoagulant Binding Sites on the Platelet Surface

1985 • 35 citations

Culture and Study of Pericytes

1990 • 35 citations

A New Link in the Brain's Defenses

1992 • 32 citations

Molecular Dissection of Effector Cell Protease Receptor-1 Recognition of Factor Xa

1996 • 24 citations

Factor Xa interacts with two sites on monocytes with different functional activities

1992 • 21 citations

The effect of calcium ionophore A23187 on tissue factor activity and mRNA in endothelial cells

1994 • 15 citations

Rapid onset of delayed traumatic intracerebral haematoma with diffuse intravascular coagulation and fibrinolysis

1982 • 15 citations

[16] Procoagulant activities expressed by peripheral blood mononuclear cells

1993 • 13 citations

Probing the Regulation of Contractility in Cardiac and Smooth Muscle Skinned Fibers with Synthetic Peptides

1993 • 10 citations