Regulation of Extrarenal Vitamin D Metabolism as a Tool for Colon and Prostate Cancer Prevention

Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β

1998 • 4,127 citations

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Food, nutrition and the prevention of cancer : a global perspective

1997 • 1,892 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor β

1998 • 1,680 citations

Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988–1994,

2002 • 1,010 citations

Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor

1998 • 987 citations

Do Sunlight and Vitamin D Reduce the Likelihood of Colon Cancer?

1980 • 879 citations

An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet‐B radiation

2002 • 765 citations

Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation

1992 • 657 citations

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

2000 • 598 citations

Geographic variation in breast cancer mortality in the United States: A hypothesis involving exposure to solar radiation

1990 • 579 citations

Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II.

1989 • 559 citations

Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3.

1998 • 360 citations

Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation.

2000 • 358 citations

Vitamin D and prostate cancer: a prediagnostic study with stored sera.

1993 • 357 citations

25-Hydroxyvitamin D3-1α-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis

2001 • 226 citations

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage

2001 • 179 citations

Liarozole Acts Synergistically with 1α,25-Dihydroxyvitamin D₃to Inhibit Growth of DU 145 Human Prostate Cancer Cells by Blocking 24-Hydroxylase Activity¹

1999 • 168 citations

1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells.

2000 • 159 citations

25-Hydroxy-Vitamin D Metabolism in Human Colon Cancer Cells during Tumor Progression

2001 • 139 citations

Vitamin D metabolism in human colon adenocarcinoma-derived Caco-2 cells: Expression of 25-hydroxyvitamin D3-1α-hydroxylase activity and regulation of sidechain metabolism

1997 • 122 citations

The protective effect of estrogen against chemically induced murine colon carcinogenesis is associated with decreased CpG island methylation and increased mRNA and protein expression of the colonic vitamin D receptor.

1999 • 114 citations

BRIEF COMMUNICATION: Growth Control of Human Colon Cancer Cells by Vitamin D and Calcium In Vitro

1992 • 101 citations

Vitamin D and prostate cancer

2001 • 63 citations

In situ mRNA hybridization analysis and immunolocalization of the vitamin D receptor in normal and carcinomatous human colonic mucosa: relation to epidermal growth factor receptor expression

2000 • 53 citations

Clonal Differences in Expression of 25-Hydroxyvitamin D3-1α-hydroxylase, of 25-Hydroxyvitamin D3-24-hydroxylase, and of the Vitamin D Receptor in Human Colon Carcinoma Cells: Effects of Epidermal Growth Factor and 1α,25-Dihydroxyvitamin D3

2002 • 50 citations

Isoflavonoids inhibit catabolism of vitamin D in prostate cancer cells

2002 • 45 citations

Liarozole Acts Synergistically with 1 ,25-Dihydroxyvitamin D3 to Inhibit Growth of DU 145 Human Prostate Cancer Cells by Blocking 24-Hydroxylase Activity

1999 • 41 citations

Biological effects of 1alpha-hydroxy- and 1beta-(hydroxymethyl)-vitamin D compounds relevant for potential colorectal cancer therapy.

1999 • 28 citations