Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is

1975 • 4,443 citations

Vitamin D

1979 • 3,814 citations

Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation

1992 • 657 citations

Newly Identified Actions of the Vitamin D Endocrine System*

1992 • 563 citations

Is vitamin D deficiency a risk factor for prostate cancer? (Hypothesis).

1990 • 514 citations

Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells.

1994 • 489 citations

Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines.

1993 • 475 citations

Effect of 1α,25-Dihydroxyvitamin D3 on the Morphologic and Biochemical Differentiation of Cultured Human Epidermal Keratinocytes Grown in Serum-Free Conditions

1986 • 460 citations

Vitamin D and prostate cancer: a prediagnostic study with stored sera.

1993 • 357 citations

Assay of circulating 1,25-dihydroxyvitamin D involving a novel single-cartridge extraction and purification procedure.

1986 • 302 citations

1,25-Dihydroxyvitamin D3 production by human keratinocytes. Kinetics and regulation.

1986 • 267 citations

Human bone cells in culture metabolize 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3.

1981 • 233 citations

Vitamin D receptor expression, 24-hydroxylase activity, and inhibition of growth by 1alpha,25-dihydroxyvitamin D3 in seven human prostatic carcinoma cell lines.

1995 • 229 citations

The human prostatic carcinoma cell line LNCaP expresses biologically active, specific receptors for 1 alpha,25-dihydroxyvitamin D3.

1992 • 226 citations

Regulation of the hydroxylation of 25-hydroxyvitamin D3 in vivo and in primary cultures of chick kidney cells.

1979 • 213 citations

Circulating vitamin D metabolites in relation to subsequent development of prostate cancer.

1996 • 181 citations

1 alpha,25-Dihydroxyvitamin D (calcitriol) inhibits the invasiveness of human prostate cancer cells.

1997 • 179 citations

Phase II trial of oral 1,25-dihydroxyvitamin D (calcitriol) in hormone refractory prostate cancer

1995 • 170 citations

Absence of Seasonal Variation in Serum Concentrations of 1,25-Dihydroxyvitamin D Despite a Rise in 25-Hydroxyvitamin D in Summer*

1981 • 158 citations

Human prostate cancer cells: inhibition of proliferation by vitamin D analogs.

1994 • 153 citations

A method for the determination of the circulating concentration of 1,25-dihydroxyvitamin D

1990 • 134 citations

Vitamin D receptor content and transcriptional activity do not fully predict antiproliferative effects of vitamin D in human prostate cancer cell lines

1997 • 132 citations

Secretion of matrix metalloproteinases and their inhibitors (tissue inhibitor of metalloproteinases) by human prostate in explant cultures: reduced tissue inhibitor of metalloproteinase secretion by malignant tissues.

1993 • 119 citations

The role of vitamin D in normal prostate growth and differentiation.

1996 • 90 citations

Extrarenal production of calcitriol.

1994 • 82 citations

Paracrine role for calcitriol in the immune system and skin creates new therapeutic possibilities for vitamin D analogs

1995 • 80 citations

The Antiproliferative and Differentiative Activities of 1,25-Dihydroxyvitamin D3 Are Potentiated by Epidermal Growth Factor and Attenuated by Insulin in Cultured Human Keratinocytes

1995 • 57 citations

Evidence for calcium-dependent control of 1,25-dihydroxyvitamin D3 production by rat kidney proximal tubules.

1986 • 50 citations

Characterization of primar cell cultures derived from rat renal proximal tubules

1989 • 41 citations

A Role for Endogenous Arachidonate Metabolites in the Regulated Expression of the 25-Hydroxyvitamin D-1-Hydroxylation Reaction in Cultured Alveolar Macrophages from Patients with Sarcoidosis*

1990 • 38 citations

Extrarenal production of calcitriol.

1990 • 37 citations

Production of 10-oxo-19-nor-25-hydroxyvitamin D3 by solubilized kidney mitochondria from chick and rat.

1985 • 31 citations

In VitroMetabolism of 25-Hydroxyvitamin D₃by Human Trophoblastic Homogenates, Mitochondria, and Microsomes: Lack of Evidence for the Presence of 25- Hydroxyvitamin D₃-lα- and 24R-Hydroxylases*

1989 • 28 citations