Histo-Blood Group Antigens as Tumor-Associated Carbohydrate Antigens and Ligands for Cell Adhesion

ELAM-1 Mediates Cell Adhesion by Recognition of a Carbohydrate Ligand, Sialyl-Le ^x

1990 • 1,315 citations

Molecular genetic basis of the histo-blood group ABO system

1990 • 1,142 citations

Aberrant Glycosylation In Tumors And Tumor-Associated Carbohydrate Antigens

1989 • 1,083 citations

Recognition by Elam-1 of the Sialyl-Le ^x Determinant on Myeloid and Tumor Cells

1990 • 976 citations

Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions.

1990 • 889 citations

A monoclonal antibody-defined antigen associated with gastrointestinal cancer is a ganglioside containing sialylated lacto-N-fucopentaose II.

1982 • 885 citations

ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA

1990 • 712 citations

Tumor-Associated Carbohydrate Antigens

1984 • 622 citations

Specific Antigen in Serum of Patients with Colon Carcinoma

1981 • 583 citations

Ulex europaeus I lectin as a marker for vascular endothelium in human tissues.

1982 • 573 citations

ABH and Related Histo‐Blood Group Antigens; Immunochemical Differences in Carrier Isotypes and Their Distribution¹

1989 • 517 citations

CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.

1991 • 505 citations

Characterization of sialosylated Lewisx as a new tumor-associated antigen.

1984 • 503 citations

A Sphingolipid Having a Novel Type of Ceramide and Lacto-N-Fucopentaose III

1971 • 486 citations

Detection of gangliosides that bind cholera toxin: Direct binding of 125I-labeled toxin to thin-layer chromatograms

1980 • 480 citations

A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1

1991 • 480 citations

Structural Studies on Human Erythrocyte Glycoproteins

1969 • 470 citations

Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3.

1986 • 456 citations

Specific interaction between Lex and Lex Determinants

1989 • 450 citations

Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope.

1988 • 419 citations

Biochemistry and Genetics of the ABO, Lewis, and P Blood Group Systems

1980 • 415 citations

Analysis of a human tumor-associated glycoprotein (TAG-72) identified by monoclonal antibody B72.3.

1986 • 408 citations

Zur Kenntnis der antifermentativen, lytischen und agglutinierenden Wirkungen des Blutserums und der Lymphe

1900 • 389 citations

Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients

1990 • 380 citations

Cloning and characterization of DNA complementary to human UDP-GalNAc: Fuc alpha 1----2Gal alpha 1----3GalNAc transferase (histo-blood group A transferase) mRNA.

1990 • 360 citations

Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A

1991 • 347 citations

Blood group ABH and Ii antigens of human erythrocytes: chemistry, polymorphism, and their developmental change.

1981 • 344 citations

A monoclonal antibody (B72.3) defines patterns of distribution of a novel tumor‐associated antigen in human mammary carcinoma cell populations

1982 • 324 citations

Ueber Agglutinationserscheinungen normalen menschlichen Blutes

1901 • 302 citations

Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6).

1984 • 285 citations

Characterization of a blood group I-active ganglioside. Structural requirements for I and i specificities.

1979 • 276 citations

Glycosphingolipids with Lewis Blood Group Activity: Uptake by Human Erythrocytes

1969 • 262 citations

Novel fucolipids accumulating in human adenocarcinoma. I. Glycolipids with di- or trifucosylated type 2 chain.

1984 • 259 citations

A Glycolipid Antigen Associated with Burkitt Lymphoma Defined by a Monoclonal Antibody

1983 • 243 citations

Quantitative and qualitative characterization of human cancer-associated serum glycoprotein antigens expressing fucosyl or sialyl-fucosyl type 2 chain polylactosamine.

1986 • 236 citations

Correlation of Expression of H/Le^Y/Le^BAntigens with Survival in Patients with Carcinoma of the Lung

1992 • 235 citations

Novel fucolipids accumulating in human adenocarcinoma. II. Selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain.

1984 • 233 citations

Generation of monoclonal antibodies reacting with normal and cancer cells of human breast.

1983 • 230 citations

Expression of Blood-Group Antigen A — A Favorable Prognostic Factor in Non-Small-Cell Lung Cancer

1991 • 221 citations

Blood Group Substances: Their Chemistry and Immunochemistry

1957 • 215 citations

Distribution of blood group antigens A, B, H, Lewisa, and Lewisb in human normal, fetal, and malignant colonic tissue.

1985 • 211 citations

Specific Interaction between Gangliotriaosylceramide (Gg3) and Sialosyllactosylceramide (GM3) as a Basis for Specific Cellular Recognition between Lymphoma and Melanoma Cells

1989 • 208 citations

Characterization of a glycosphingolipid antigen defined by the monoclonal antibody MBr1 expressed in normal and neoplastic epithelial cells of human mammary gland.

1984 • 205 citations

Blood group A cross-reacting epitope defined by monoclonal antibodies NCC-LU-35 and -81 expressed in cancer of blood group O or B individuals: its identification as Tn antigen.

1985 • 204 citations

Blood group i and I activities of “lacto-N-norhexaosylceramide” and its analogues: The structural requirements for i-specificities

1978 • 199 citations

<italic>Brief Communication:</italic> Blood Group MN Antigens and Precursors in Normal and Malignant Human Breast Glandular Tissue<xref ref-type="fn" rid="fn2">2</xref>

1975 • 192 citations

The monoclonal antibody directed to difucosylated type 2 chain (Fuc alpha 1 leads to 2Gal beta 1 leads to 4[Fuc alpha 1 leads to 3]GlcNAc; Y Determinant).

1983 • 184 citations

Isoantigenic expression of Forssman glycolipid in human gastric and colonic mucosa: Its possible identity with “A-like antigen” in human cancer

1977 • 181 citations

Immunologic Relationship between Blood Group Substances and a Fucose-Containing Glycolipid of Human Adenocarcinoma

1967 • 179 citations

Carbohydrate-carbohydrate interaction as an initial step in cell recognition

1991 • 174 citations

Ueber Agglutiunationserscheinungen normalen menschlichen Bluters

1901 • 174 citations

Monoclonal antibody against a Burkitt lymphoma-associated antigen.

1981 • 171 citations

Cell adhesion in a dynamic flow system as compared to static system. Glycosphingolipid-glycosphingolipid interaction in the dynamic system predominates over lectin- or integrin-based mechanisms in adhesion of B16 melanoma cells to non-activated endothelial cells.

1992 • 153 citations

Serum sialyl Tn as an independent predictor of poor prognosis in patients with epithelial ovarian cancer.

1992 • 147 citations

Selectin GMP-140 (CD62; PADGEM) binds to sialosyl-Lea and sialosyl-Lex, and sulfated glycans modulate this binding

1991 • 134 citations

Immunoglobulin G3 monoclonal antibody directed to Tn antigen (tumor-associated alpha-N-acetylgalactosaminyl epitope) that does not cross-react with blood group A antigen.

1988 • 130 citations

Spectrum of sialylated and nonsialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. Dependence of the carbohydrate binding activity on E-selectin density.

1992 • 130 citations

Isolation to homogeneity and partial characterization of a histo-blood group A defined Fuc alpha 1----2Gal alpha 1----3-N-acetylgalactosaminyltransferase from human lung tissue.

1990 • 124 citations

Isoimmunization by a New Blood Factor in Tumor Cells

1951 • 124 citations

Acquired Hemolytic Anemia with Polyagglutinability of Red Blood Cells Due to a New Factor Present in Normal Human Serum (Anti-Tn)

1959 • 122 citations

Carbohydrates in Solution

1973 • 122 citations

Human blood-group MN and precursor specificities: structural and biological aspects

1975 • 121 citations

Sphingoglycolipids with Leb activity, and the co-presence of Lea-, Leb-glycolipids in human tumor tissue

1970 • 116 citations

Cryptic A‐Like Receptor Sites in Human Erythrocyte Glycoproteins: Proposed Nature of Tn‐Antigen

1974 • 111 citations

A radioimmunoassay for the detection of a human tumor‐associated glycoprotein (tag‐72) using monoclonal antibody B72.3

1986 • 110 citations

Isolation of a Glycolipid Containing Fucose, Galactose, Glucose, and Glucosamine from Human Cancerous Tissue

1964 • 109 citations

GENETIC AND BIOCHEMICAL ASPECTS OF HUMAN BLOOD-GROUP A−, B−, H−, Lea − AND Leb− SPECIFICITY

1969 • 106 citations

Enzymic conversion of “H1-glycolipid” to a or B-glycolipid and deficiency of these enzyme activities in adenocarcinoma

1973 • 101 citations

A and B Antigens of Tumors Arising From Urinary Epithelium

1961 • 101 citations

Human Blood and Serum Groups

1970 • 98 citations

Characterization of monoclonal antibodies specific for the Lewis a human blood group determinant.

1983 • 97 citations

A monoclonal antibody that recognizes a cluster of a disaccharide, NeuAc alpha(2—-6)GalNAc, in mucin-type glycoproteins.

1988 • 97 citations

A monoclonal antibody against human colonic adenoma recognizes difucosylated Type-2-blood-group chains

1983 • 96 citations

A specific cell surface glycoconjugate controlling cell motility: evidence by functional monoclonal antibodies that inhibit cell motility and tumor cell metastasis

1991 • 96 citations

Blood group MN specific substances and precursors in normal and malignant human breast tissues

1974 • 94 citations

Isoantigens A, B, and H in benign and malignant lesions of the cervix.

1969 • 92 citations

Novel fucolipids of human adenocarcinoma: characterization of the major Ley antigen of human adenocarcinoma as trifucosylnonaosyl Ley glycolipid (III3FucV3FucVI2FucnLc6).

1986 • 89 citations

Mouse monoclonal antibody F-3 recognizes the difucosyl type-2 blood group structure

1983 • 89 citations

Differential tissue expression of the Lewis blood group antigens: enzymatic, immunohistologic, and immunochemical evidence for Lewis a and b antigen expression in Le(a-b-) individuals

1991 • 88 citations

Novel fucolipids of human adenocarcinoma: monoclonal antibody specific for trifucosyl Ley (III3FucV3FucVI2FucnLc6) and a possible three-dimensional epitope structure.

1986 • 78 citations

Immunocytochemical studies of blood group A, H, I, and i antigens in gastric mucosae of infants with normal gastric histology and of patients with gastric carcinoma and chronic benign peptic ulceration.

1981 • 78 citations

Loss of isoantigens A, B, and H in carcinoma of the lung.

1969 • 76 citations

A New Human Breast Carcinoma Cell Line (PMC42) With Stem Cell Characteristics. I. Morphologic Characterization

1983 • 76 citations

Elevated serum levels of Dupan-2 in pancreatic cancer patients negative for Lewis blood group phenotype

1991 • 76 citations

Carcinoembryonic Antigen and Blood Group Substances in Carcinomas of the Stomach and Colon 2

1974 • 76 citations

Loss of Gastro-intestinal-specific Antigen in Neoplasia

1962 • 73 citations

Extended type 1 chain glycosphingolipids: dimeric Lea (III4V4Fuc2Lc6) as human tumor-associated antigen

1991 • 70 citations

A, B, and O substances in gastrointestinal carcinoma.

1966 • 70 citations

Incompatible A antigen expressed in tumors of blood group O individuals: immunochemical, immunohistologic, and enzymatic characterization.

1986 • 70 citations

Carcinoembryonic antigen and blood group substances.

1973 • 69 citations

Quantitative and qualitative characterization of human cancer-associated serum glycoprotein antigens expressing epitopes consisting of sialyl or sialyl-fucosyl type 1 chain.

1988 • 69 citations

Analysis of the expression of H, Lewis, X, Y and precursor blood group determinants in saliva and red cells using a panel of mouse monoclonal antibodies

1984 • 69 citations

A-like blood group antigen in gastric cancer cells of patients in blood groups Q or B.

1970 • 69 citations

BLOOD-GROUP PRECURSORS AND CANCER-RELATED ANTIGENS

1975 • 67 citations

Metastatic Potential of Colon Carcinoma

1990 • 67 citations

LOSS OF EPITHELIAL BLOOD GROUP SUBSTANCE A IN ORAL CARCINOMAS

1973 • 64 citations

New directions in cancer therapy based on aberrant expression of glycosphingolipids: anti-adhesion and ortho-signaling therapy.

1991 • 63 citations

Glycolipids of gastric cancer

1981 • 63 citations

Human blood and serum groups

1969 • 60 citations

Blood group A-like glycolipid and a novel Forssman antigen in the hepatocarcinoma of a blood group O individual.

1981 • 52 citations

Loss of Lewis antigen expression on erythrocytes in some cancer patients with high serum CA19-9 levels.

1987 • 50 citations

Lea-active heptaglycosylceramide, a hybrid of type 1 and type 2 chain, and the pattern of glycolipids with Lea, Leb, X (Lex), and Y (Ley) determinants in human blood cell membranes (ghosts). Evidence that type 2 chain can elongate repetitively but type 1 chain cannot.

1985 • 49 citations

A carbohydrate epitope associated with human squamous lung cancer

1989 • 49 citations

LOSS OF EPITHELIAL BLOOD GROUP ANTIGENS A AND B IN ORAL PREMALIGNANT LESIONS

1975 • 49 citations

Adaptation of mass spectrometry for the analysis of tumor antigens as applied to blood group glycolipids of a human gastric carcinoma.

1980 • 46 citations

Molisch-positive Mucopolysaccharides of Gastric Cancers as Compared with the Corresponding Components of Gastric Mucosae

1958 • 46 citations

A preliminary study of blood group substances A and B in oral epithelium exhibiting atypia

1971 • 44 citations

A series of disialogangliosides with binary 2→3 sialosyllactosamine structure, defined by monoclonal antibody NUH2, are oncodevelopmentally regulated antigens

1989 • 44 citations

Isolation, Characterization, and Biosynthesis of Forssman Antigen in Human Lung and Lung Carcinoma&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt;

1980 • 44 citations

Recent studies of glycolipid and glycoprotein profiles and characterization of the major glycolipid antigen in gastric cancer of a patient of blood group genotype pp (Tja-) first studied in 1951.

1982 • 40 citations

Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells

1992 • 38 citations

Deletion of Histo-blood Group A and B Antigens and Expression of Incompatible A Antigen in Ovarian Cancer

1989 • 37 citations

Immunochemical Studies on the Carbohydrate Moiety of Water Soluble Blood Group A, B, H, Le^a, and Le^b Substances and Their Precursor I Antigens

1973 • 36 citations

Relationship of Carcinoembryonic Antigen to Blood Substances a and i: Evidence That the Antigenic Sites Are on Different Molecules

1974 • 35 citations

Molisch-positive Mucopolysaccharides of Gastric Cancers as Compared with the Corresponding Components of Gastric Mucosae

1958 • 34 citations

Human IgG3 monoclonal antibody directed to an unbranched repeating type 2 chain (Gal beta 1----4GlcNAc beta 1----3Gal beta 1----4GlcNAc beta 1----3Gal beta 1----R) which is highly expressed in colonic and hepatocellular carcinoma.

1989 • 34 citations

A monoclonal antibody with anti‐burkitt lymphoma specificity. I. Analysis of human haematopoietic and lymphoid cell lines

1982 • 34 citations

Polysaccharides and a Glycidamin in the Tissue of Gastric Cancer

1949 • 33 citations

A novel tumor-associated, developmentally regulated glycolipid antigen defined by monoclonal antibody ACFH-18.

1988 • 32 citations

Extended type‐1 chain glycosphingolipid antigens

1992 • 32 citations

Coexpression of Sialosyl‐Tn (NeuAcα2→6GalNAcαl→0‐Ser/Thr) and Tn (GalNAcα1→O‐Ser/Thr) Blood Group Antigens on Tn Erythrocytes¹

1989 • 31 citations

In vitro and in vivo antitumor effects of murine monoclonal antibody NCC-ST-421 reacting with dimeric Le(a) (Le(a)/Le(a)) epitope.

1991 • 29 citations

Human Blood Group Isoantigen Expression on Normal and Malignant Gastric Epithelium Studied With Anti-A and Anti-B Monoclonal Antibodies&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;

1983 • 27 citations

p53 in Human Cancer

1995 • 26 citations

Blood group substances: Their chemistry and immunochemistry

1956 • 26 citations

Specificity and immunobiological properties of monoclonal antibody IMH2, established after immunization with Le(b)/Le(a) glycosphingolipid, a novel extended type 1 chain antigen.

1992 • 21 citations

Blood group and tissue genetic markers in familial adenocarcinoma: potential specific immunotherapy.

1978 • 21 citations

Advances in Human Genetics. Vol. 7

1978 • 20 citations

Characterization of glycolipids from the gastric cancer of a patient of p,O,Le(a-,b+) blood type: presence of incompatible blood group antigens in tumor tissues.

1987 • 18 citations

Biochemical Studies on Carbohydrates

1952 • 17 citations

Molisch-positive Mucopolysaccharides of Gastric Cancers as Compared with the Corresponding Components of Gastric Mucosae:Fifth Report: On MPSs (Mucopolysaccharides) III

1958 • 17 citations

Immunochemical Studies on Gastric Cancer Polysaccharide

1962 • 16 citations

Comparison of the Group Carbohydrate of Gastric Cancer with the Corresponding Carbohydrate of Gastric Mucosa

1953 • 16 citations

Interaction of blood-group MN-like cancer antigen and human cytotoxin

1974 • 12 citations

Biochemical studies on carbohydrates. CLVI. On the sugar components of the hexosamine-containing carbohydrates from gastric cancers, normal human gastric mucosa and human liver and of the glacial acetic acid-soluble proteins from those tissues as well as a metastasis in liver of gastric cancer.

1952 • 11 citations

[Initial basic and clinical evaluation of a solid-phase immunoradiometric assay for sialyl SSEA-1 antigen: 1. Evaluation of assay conditions and normal values].

1987 • 11 citations

Deleted Work

1955 • 0 citations