Molecular Mechanisms of Action Induced by 5-HT3 Receptors in a Neuronal Cell Line and by 5-HT2 Receptors in a Glial Cell Line

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Endothelium‐derived relaxing and contracting factors

1989 • 2,017 citations

Biosynthesis of nitric oxide from l-arginine

1989 • 1,220 citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

1982 • 1,049 citations

Cyclic GMP synthesis and function.

1987 • 871 citations

Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding

1987 • 866 citations

MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors

1984 • 437 citations

Arginine is a physiological precursor of endothelium-derived nitric oxide

1988 • 392 citations

The pharmacology and function of 5-HT3receptors

1986 • 380 citations

5-Hydroxytryptamine Receptor Subtypes

1988 • 361 citations

5-HT3 receptors mediate rapid responses in cultured hippocampus and a clonal cell line

1988 • 261 citations

cDNA cloning of a serotonin 5-HT1C receptor by electrophysiological assays of mRNA-injected Xenopus oocytes.

1987 • 201 citations

Serotonin-stimulated phosphoinositide turnover: mediation by the S2 binding site in rat cerebral cortex but not in subcortical regions.

1985 • 197 citations

Messenger RNA from human brain induces drug- and voltage-operated channels in Xenopus oocytes

1984 • 192 citations

[26] Culture and characteristics of hormone-responsive neuroblastoma x glioma hybrid cells

1985 • 160 citations

The properties of 5‐HT₃ receptors in clonal cell lines studied by patch‐clamp techniques

1989 • 129 citations

Identification of serotonin 5-HT3 recognition sites by radioligand binding in NG108-15 neuroblastoma-glioma cells

1987 • 99 citations

Stimulation of Ca²⁺ efflux from fura‐2‐loaded platelets activated by thrombin or phorbol myristate acetate

1987 • 96 citations

Characterization of neurotransmitter receptor-mediated phosphatidylinositol hydrolysis in the rat hippocampus

1984 • 86 citations

Kinetics of the membrane current mediated by serotonin 5‐HT3 receptors in cultured mouse neuroblastoma cells.

1989 • 76 citations

A novel, specific binding protein assay for quantitation of intracellular inositol 1,3,4,5‐tetrakisphosphate (InsP₄) using a high‐affinity InsP₄ receptor from cerebellum

1989 • 68 citations

Bradykinin regulates the level of guanosine 3′,5′-cyclic monophosphate (cyclic GMP) in neural cell lines

1984 • 60 citations

Stimulation of Phosphoinositide Hydrolysis by Serotonin in C6 Glioma Cells

1987 • 57 citations

Serotonin regulates cytosolic Ca2+ activity and membrane potential in a neuronal and in a glial cell line via 5-HT3 and 5-HT2 receptors by different mechanisms

1989 • 52 citations

Pharmacologic responses of cells of a neuroblastoma x glioma hybrid clone and modulation of synapses between hybrid cells and mouse myotubes

1978 • 50 citations

Antagonism of 5-HT3 receptor mediated currents in murine N1E-115 neuroblastoma cells by (+)-tubocurarine

1990 • 44 citations

Memantine (1-amino-3,5-dimethyladamantane) blocks the serotonin-induced depolarization response in a neuronal cell line

1988 • 44 citations

Mechanism of stimulation of cyclic‐GMP level in a neuronal cell line mediated by serotonin (5‐HT₃) receptors

1990 • 40 citations

Polyploid rat glioma cells

1982 • 31 citations

Serotonin-receptor coupled with membrane electrogenesis in a rat glioma clone

1984 • 30 citations

Activation of a K+ conductance by bradykinin and by inositol-1,4,5-trisphosphate in rat glioma cells: involvement of intracellular and extracellular Ca2+

1990 • 28 citations

Mechanisms for activation and subsequent removal of cytosolic Ca2+ in bradykinin-stimulated neuronal and glial cell lines

1990 • 26 citations