Apoptosis in the liver and its role in hepatocarcinogenesis.

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Developmental cell death: morphological diversity and multiple mechanisms

1990 • 1,695 citations

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

1995 • 1,171 citations

The morphology of various types of cell death in prenatal tissues

1973 • 716 citations

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

1995 • 706 citations

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

1992 • 675 citations

Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy

1996 • 508 citations

Internucleosomal DNA Cleavage Should not be the Sole Criterion for Identifying Apoptosis

1992 • 462 citations

Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats

1990 • 457 citations

Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters

1984 • 369 citations

Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release.

1995 • 332 citations

Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver.

1994 • 274 citations

DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion.

1990 • 249 citations

Hepatocyte apoptosis: Is transforming growth factor-B1 the kiss of death? Oberhammer FA, Pavelka M, Sharma S, Tietenbacher R, Purchio AF, Bursch W, Schulte-Hermann R. Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor β1. Proc Natl Acad Sci USA 1992;89:5408–5412

1993 • 233 citations

Cell death: programmed, apoptosis, necrosis, or other?

1995 • 220 citations

Transforming growth factor-β 1 as a signal for induction of cell death by apoptosis

1993 • 173 citations

Single GST-P positive liver cells — putative initiated. hepatocytes

1987 • 170 citations

Inherent increase of apoptosis in liver tumors: Implications for carcinogenesis and tumor regression

1997 • 150 citations

Ultrastructural study of the normal degeneration of the intersegmental muscles of Antheraea polyphemus and Manduca sexta (Insecta, lepidoptera) with particular reference to cellular autophagy

1977 • 131 citations

Apoptosis: Cell Death Under Homeostatic Control

1987 • 98 citations

Active cell death (apoptosis) in liver biology and disease.

1995 • 94 citations

Changes in the Structure and Function of the Multicatalytic Proteinase (Proteasome) during Programmed Cell Death in the Intersegmental Muscles of the Hawkmoth, Manduca sexta

1995 • 86 citations

Effects of polychlorinated biphenyls in rat liver: Quantitative analysis of enzyme-altered foci

1991 • 61 citations

Transforming growth factor beta1-induced cell death in preneoplastic foci of rat liver and sensitization by the antiestrogen tamoxifen

1996 • 33 citations

Different inhibition of DNA synthesis by transforming growth factor β and phenobarbital on GST-P-positive and GST-P-negative hepatocytes

1993 • 31 citations

Abundant TGFα a precursor and EGF receptor expression as a possible mechanism for the preferential growth of carcinogeninduced preneoplastic and neoplastic hepatocytes in rats

1994 • 24 citations

Cell Suicide and Cell Death

1971 • 24 citations