Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

1989 • 1,237 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1988 • 899 citations

Interleukin‐6 and α‐2‐macroglobulin indicate an acute‐phase state in Alzheimer's disease cortices

1991 • 484 citations

Protease nexin-II, a potent anti-chymotrypsin, shows identity to amyloid β-protein precursor

1989 • 437 citations

Expression of β amyloid protein precursor mRNAs: Recognition of a novel alternatively spliced form and quantitation in alzheimer's disease using PCR

1990 • 426 citations

Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth

1988 • 337 citations

Prothrombin mRNA is expressed by cells of the nervous system

1991 • 337 citations

Astrocytes Synthesize Angiotensinogen in Brain

1988 • 321 citations

Thrombin modulates and reverses neuroblastoma neurite outgrowth.

1988 • 318 citations

Platelet Coagulation Factor XI _a -Inhibitor, a Form of Alzheimer Amyloid Precursor Protein

1990 • 299 citations

Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.

1985 • 220 citations

Sequence homology between human .alpha.1-antichymotrypsin, .alpha.1-antitrypsin, and antithrombin III

1983 • 204 citations

General and dramatic glial reaction in Alzheimer brains

1990 • 193 citations

Glial fibrillary acidic protein and Alzheimer‐type senile dementia

1980 • 176 citations

Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA.

1989 • 141 citations

Plasma protease inhibitors in mouse and man: divergence within the reactive centre regions

1984 • 135 citations

Isolation of a cDNA clone for human antithrombin III.

1983 • 134 citations

α1-Antitrypsin and α1-antichymotrypsin are in the lesions of Alzheimerʼs disease

1992 • 128 citations

Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases.

1990 • 111 citations

Distribution pattern and functional state of ?1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease

1991 • 96 citations

Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders

1991 • 89 citations

Production of thrombin and antithrombin III by brain and astroglial cell cultures

1991 • 88 citations

Serum amyloid P immunoreactivity in hippocampal tangles, plaques and vessels: implications for leakage across the blood-brain barrier in Alzheimer's disease

1990 • 82 citations

Immunocytochemical properties of Alzheimer straight filaments

1987 • 65 citations

Distribution of the Protease Inhibitor α₁-Antichymotrypsin in Cerebral and Systemic Amyloid

1990 • 63 citations

Enter a protease inhibitor

1988 • 62 citations

Human fibroblasts accelerate the inhibition of thrombin by protease nexin.

1986 • 57 citations

Protease nexin I immunostaining in alzheimer's disease

1989 • 50 citations

Serum amyloid p and related molecules associated with the acute-phase response in alzheimer's disease

1992 • 23 citations

Inhibitors of Urokinase and Thrombin in Cultured Neural Cells

1991 • 21 citations

Demonstration of an active component of inter-α-trypsin inhibitor in the brains of Alzheimer type dementia

1991 • 19 citations