Production of thrombin and antithrombin III by brain and astroglial cell cultures

Van Damme A.

1986 • 3,477 citations

The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

1973 • 1,363 citations

α1-Antitrypsin and the serpins: variation and countervariation

1985 • 384 citations

Prothrombin mRNA is expressed by cells of the nervous system

1991 • 337 citations

Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth

1988 • 337 citations

Phosphoinositides in mitogenesis: Neomycin inhibits thrombin-stimulated phosphoinositide turnover and initiation of cell proliferation

1985 • 332 citations

Astrocytes Synthesize Angiotensinogen in Brain

1988 • 321 citations

Thrombin modulates and reverses neuroblastoma neurite outgrowth.

1988 • 318 citations

Characterization of the complementary deoxyribonucleic acid and gene coding for human prothrombin

1983 • 299 citations

A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins

1986 • 297 citations

Binding of thrombin to subendothelial extracellular matrix. Protection and expression of functional properties.

1989 • 212 citations

Neuronal plasminogen activators: cell surface binding sites and involvement in neurite outgrowth

1989 • 204 citations

Reciprocal Modulation of Astrocyte Stellation by Thrombin and Protease Nexin‐1

1990 • 198 citations

Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells.

1990 • 180 citations

Pertussis toxin inhibits thrombin-induced activation of phosphoinositide hydrolysis and Na+/H+ exchange in hamster fibroblasts.

1986 • 165 citations

Localization of preangiotensinogen messenger RNA sequences in the rat brain.

1986 • 156 citations

Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA.

1989 • 141 citations

Isolation of a cDNA clone for human antithrombin III.

1983 • 134 citations

Thrombin and its inhibitors regulate morphological and biochemical differentiation of astrocytes in vitro

1990 • 87 citations

Thrombin is a potent mitogen for rat astroblasts but not for oligodendroblasts and neuroblasts in primary culture

1987 • 87 citations

Effect of proteases and their inhibitors on neurite outgrowth from neonatal mouse sensory ganglia in culture

1986 • 80 citations

Angiotensinogen production by rat astroglial cells in vitro and in vivo

1990 • 74 citations

Double-Signal Hypothesis for Thrombin Initiation of Cell Proliferation

1986 • 72 citations

Acute phase protein stimulation by alpha 1-antichymotrypsin-cathepsin G complexes. Evidence for the involvement of interleukin-6.

1990 • 68 citations

Plasminogen activator is a mitogen for astrocytes in developing cerebellum

1985 • 64 citations

Developmental transition in plasticity properties of differentiating astrocytes: Age‐related biochemical profile of plasminogen activators in astroglial cultures

1990 • 63 citations

Mitogenic signals for thrombin in mesangial cells: regulation of phospholipase C and PDGF genes

1989 • 61 citations

Characterization of an inhibitor of neuronal plasminogen activator released by heart cells

1987 • 38 citations

Enhanced release of plasminogen activator inhibitor(s) but not of plasminogen activators by cultured rat glial cells treated with interleukin‐1

1990 • 33 citations

Mediation of cellular events by thrombin.

1986 • 19 citations