A TROSY CPMG sequence for characterizing chemical exchange in large proteins.

Attenuated T ₂ relaxation by mutual cancellation of dipole–dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

1997 • 2,375 citations

Data Analysis and Regression.

1979 • 1,739 citations

Data Analysis and Regression: A Second Course in Statistics

1977 • 1,577 citations

Attenuated T₂ relaxation by mutual cancellation of dipole–dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

2021 • 957 citations

Sensitivity improvement in proton-detected two-dimensional heteronuclear correlation NMR spectroscopy

1991 • 931 citations

A Relaxation-Compensated Carr−Purcell−Meiboom−Gill Sequence for Characterizing Chemical Exchange by NMR Spectroscopy

1999 • 648 citations

Improved Sensitivity of HSQC Spectra of Exchanging Protons at Short Interscan Delays Using a New Fast HSQC (FHSQC) Detection Scheme That Avoids Water Saturation

1995 • 621 citations

Nuclear Magnetic Resonance Study of the Protolysis of Trimethylammonium Ion in Aqueous Solution—Order of the Reaction with Respect to Solvent

1963 • 527 citations

Interference effects in the relaxation of a pair of unlike nuclei

1984 • 376 citations

TROSY-type Triple-Resonance Experiments for Sequential NMR Assignments of Large Proteins

1999 • 319 citations

Direct Measurements of the Dissociation-Rate Constant for Inhibitor-Enzyme Complexes via the T1ρ and T2 (CPMG) Methods

1994 • 278 citations

Monitoring Macromolecular Motions on Microsecond to Millisecond Time Scales by R₁_ρ−R₁ Constant Relaxation Time NMR Spectroscopy

1996 • 271 citations

Studies of chemical exchange by nuclear magnetic relaxation in the rotating frame

1970 • 260 citations

Suppression of the effects of cross-correlation between dipolar and anisotropic chemical shift relaxation mechanisms in the measurement of spin-spin relaxation rates

1992 • 255 citations

Longitudinal and Transverse ¹H−¹⁵N Dipolar/¹⁵N Chemical Shift Anisotropy Relaxation Interference: Unambiguous Determination of Rotational Diffusion Tensors and Chemical Exchange Effects in Biological Macromolecules

1998 • 250 citations

Probing molecular motion by NMR

1997 • 241 citations

Structure of yeast triosephosphate isomerase at 1.9-.ANG. resolution

1990 • 237 citations

On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase

1981 • 216 citations

Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-.ANG. resolution: implications for catalysis

1990 • 216 citations

Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analog of the intermediate on the reaction pathway

1991 • 212 citations

Protein dynamics studied by rotating frame 15N spin relaxation times

1993 • 178 citations

Sensitivity improvement in proton-detected two-dimensional heteronuclear relay spectroscopy

1991 • 167 citations

Dynamics of the Flexible Loop of Triose-Phosphate Isomerase: The Loop Motion Is Not Ligand Gated

1995 • 160 citations

Untitled

1997 • 140 citations

Sensitivity Improvement of Transverse Relaxation-Optimized Spectroscopy

1999 • 124 citations

Using Amide ¹H and ¹⁵N Transverse Relaxation To Detect Millisecond Time-Scale Motions in Perdeuterated Proteins: Application to HIV-1 Protease

1998 • 119 citations

Correlation between binding and dynamics at SH2 domain interfaces

1998 • 110 citations

Transverse-Relaxation-Optimized (TROSY) Gradient-Enhanced Triple-Resonance NMR Spectroscopy

1999 • 106 citations

Nitrogen-15 chemical shifts of backbone amides in bovine pancreatic trypsin inhibitor and apamin

1989 • 88 citations

The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes

1991 • 81 citations

Anion binding at the active site of trypanosomal triosephosphate isomerase

1991 • 29 citations

Local mobility of 15N labeled biomolecules characterized through cross-correlation rates: Applications to paramagnetic proteins.

1998 • 22 citations

Performance of a neural-network-based determination of amino acid class and secondary structure from 1H-15N NMR data.

1997 • 20 citations

Cited By (0)

Loading...