The Energy Landscapes and Motions of Proteins

On the Temperature Dependence of Cooperative Relaxation Properties in Glass-Forming Liquids

1965 • 5,553 citations

Spin glasses: Experimental facts, theoretical concepts, and open questions

1986 • 4,903 citations

The fluctuation-dissipation theorem

1966 • 4,550 citations

Spin Glass Theory and Beyond

1986 • 3,761 citations

The Physics of Amorphous Solids

1986 • 1,892 citations

Mössbauer Spectroscopy

1971 • 1,882 citations

Dynamics of ligand binding to myoglobin

1975 • 1,616 citations

Spin glasses and the statistical mechanics of protein folding.

1987 • 1,608 citations

The Physics of Amorphous Solids

1983 • 1,570 citations

Are there pathways for protein folding?

1968 • 1,496 citations

Hydrogen exchange and structural dynamics of proteins and nucleic acids

1983 • 1,329 citations

Random-energy model: An exactly solvable model of disordered systems

1981 • 1,294 citations

Dynamics of Proteins and Nucleic Acids

1987 • 1,222 citations

Temperature-dependent X-ray diffraction as a probe of protein structural dynamics

1979 • 1,136 citations

Biological Applications of Raman Spectroscopy

2000 • 1,100 citations

Conformational Substates in Proteins

1988 • 984 citations

Scaling concepts for the dynamics of viscous liquids near an ideal glassy state

1989 • 969 citations

Packing Structures and Transitions in Liquids and Solids

1984 • 964 citations

Models of the glass transition

1986 • 935 citations

Spin Glasses

1991 • 830 citations

Protein states and proteinquakes.

1985 • 810 citations

Proteins: A Theoretical Perspective of Dynamics, Structure and Thermodynamics

1990 • 758 citations

Intermediates and barrier crossing in a random energy model (with applications to protein folding)

1989 • 748 citations

Persistent Spectral Hole-Burning: Science and Applications

1988 • 672 citations

Multiple Conformational States of Proteins: A Molecular Dynamics Analysis of Myoglobin

1987 • 663 citations

Time-Scale Invariance in Transport and Relaxation

1991 • 523 citations

Diffusion in a rough potential.

1988 • 519 citations

Energetics of Ligand Binding to Proteins

1975 • 519 citations

Enhanced sampling in molecular dynamics: use of the time-dependent Hartree approximation for a simulation of carbon monoxide diffusion through myoglobin

1990 • 509 citations

The simplest spin glass

1984 • 468 citations

Stable and metastable states in mean-field Potts and structural glasses

1987 • 444 citations

Dynamics of ligand binding to heme proteins

1979 • 440 citations

Amorphous Solids

1981 • 422 citations

Glassy behavior of a protein

1989 • 392 citations

Ligand binding to heme proteins: connection between dynamics and function

1991 • 375 citations

Mean-field theory of the Potts glass

1985 • 369 citations

Photophysics and reactivity of heme proteins: a femtosecond absorption study of hemoglobin, myoglobin, and protoheme

1988 • 360 citations

Molecular dynamics of native protein

1983 • 358 citations

Rebinding and relaxation in the myoglobin pocket

1987 • 351 citations

CO binding to heme proteins: A model for barrier height distributions and slow conformational changes

1983 • 345 citations

Glucose-induced conformational change in yeast hexokinase.

1978 • 305 citations

An X-ray study of azide methaemoglobin

1966 • 294 citations

Anatomy of a Conformational Change: Hinged "Lid" Motion of the Triosephosphate Isomerase Loop

1990 • 282 citations

Proteins and pressure

1990 • 278 citations

Characterization of the distribution of internal motions in the basic pancreatic trypsin inhibitor using a large number of internal NMR probes

1983 • 270 citations

Fluctuations in Protein Structure from X-Ray Diffraction

1984 • 254 citations

Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K.

1982 • 247 citations

A mutant T4 lysozyme displays five different crystal conformations

1990 • 231 citations

Enzyme Dynamics: The Statistical Physics Approach

1979 • 220 citations

Ligand binding and protein relaxation in heme proteins: a room temperature analysis of nitric oxide geminate recombination

1991 • 207 citations

Nanosecond absorption spectroscopy of hemoglobin: elementary processes in kinetic cooperativity.

1983 • 207 citations

The Relaxation Distribution Function of Polyisobutylene in the Transition from Rubber-Like to Glass-Like Behavior

1953 • 194 citations

Molecular dynamics of native protein

1983 • 190 citations

Mean-Field Model for Protein Folding

1988 • 187 citations

Spin glass model of learning by selection.

1986 • 156 citations

A model of protein conformational substates

1985 • 150 citations

Protein fluctuations, distributed coupling, and the binding of ligands to heme proteins

1988 • 146 citations

Structure, Dynamics, and Reactivity in Hemoglobin

1985 • 146 citations

Theory of relaxation in viscous liquids and glasses

1984 • 143 citations

Structure of carboxymyoglobin in crystals and in solution.

1979 • 135 citations

Hole-Burning Spectroscopy and Relaxation Dynamics of Amorphous Solids at Low Temperatures

1987 • 128 citations

Linkage of Functional and Structural Heterogeneity in Proteins: Dynamic Hole Burning in Carboxymyoglobin

1987 • 125 citations

Conformational substates and motions in myoglobin. External influences on structure and dynamics

1990 • 105 citations

Stretched exponential relaxation in systems with random free energies

1985 • 101 citations

Iron-carbonyl bond geometries of carboxymyoglobin and carboxyhemoglobin in solution determined by picosecond time-resolved infrared spectroscopy.

1988 • 101 citations

Molecular dynamics simulation of photodissociation of carbon monoxide from hemoglobin.

1985 • 97 citations

Orientation of carbon monoxide and structure-function relationship in carbonmonoxymyoglobin.

1988 • 92 citations

The Nonergodic (“Spin-Glass–Like”) Phase of Heteropolymer with Quenched Disordered Sequence of Links

1989 • 85 citations

Excitations in Metmyoglobin crystals at low temperatures

1984 • 84 citations

Application of linear free energy relations to protein conformational changes: the quaternary structural change of hemoglobin.

1991 • 75 citations

Inhomogeneous broadening in spectral bands of carbonmonoxymyoglobin. The connection between spectral and functional heterogeneity

1990 • 72 citations

Reactive line-shape narrowing in low-temperature inhomogeneous geminate recombination of CO to myoglobin

1988 • 68 citations

The effect of quaternary structure on the kinetics of conformational changes and nanosecond geminate rebinding of carbon monoxide to hemoglobin.

1988 • 61 citations

Protein conformational relaxation following photodissociation of carbon monoxide from carbonmonoxymyoglobin: picosecond circular dichroism and absorption studies

1991 • 60 citations

Hemoglobin and Oxygen Binding

1984 • 58 citations

Relaxation to Equilibrium in the Random Energy Model

1989 • 58 citations

Movement of Fe with respect to the heme plane in the R-T transition of carp hemoglobin. An extended x-ray absorption fine structure study.

1986 • 41 citations

Metastable photoproducts from carbon monoxide myoglobin.

1986 • 39 citations

Dynamics of the quaternary conformational change in trout hemoglobin

1991 • 39 citations

The Debye‐Waller factor: From villain to hero in protein crystallography

1989 • 30 citations

Probing of conformational relaxation processes of proteins by frequency labeling of optical states

1989 • 30 citations

Power Law Relaxation in the Random Energy Model

1987 • 28 citations

Iceberg deterioration

1977 • 24 citations

Spin Glasses

1989 • 21 citations

Dynamical simulation of rate constants in protein-ligand interactions

1988 • 15 citations

Deleted Work

1955 • 0 citations