Characterization of hydrogen peroxide toxicity in cultured rat forebrain neurons.

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1980 • 4,407 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

Reactive Oxygen Species and the Central Nervous System

1992 • 2,931 citations

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1993 • 1,692 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

Photochemically generated cytosolic calcium pulses and their detection by fluo-3

1989 • 820 citations

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

1995 • 773 citations

A radical hypothesis for neurodegeneration

1993 • 727 citations

Rapid Communication: Oxidative Stress Induces Apoptosis in Embryonic Cortical Neurons

1994 • 588 citations

Free radical damage to protein and DNA: Mechanisms involved and relevant observations on brain undergoing oxidative stress

1992 • 539 citations

Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons

1994 • 494 citations

Oxidative stress: Free radical production in neural degeneration

1994 • 483 citations

Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide

1995 • 384 citations

Intense oxidative DNA damage promoted by <scp>l</scp>‐DOPA and its metabolites implications for neurodegenerative disease

1994 • 294 citations

Mitochondria and Na+/Ca2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons

1995 • 292 citations

A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture

1995 • 260 citations

Calcium ions and oxidative cell injury

1992 • 246 citations

Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.

1993 • 213 citations

Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons

1994 • 208 citations

Oxygen radicals as key mediators in neurological disease: Fact or fiction?

1992 • 186 citations

Probing Mitochondria in Living Cells with Rhodamine 123

1982 • 184 citations

Calcium chelator Quin 2 prevents hydrogen‐peroxide‐induced DNA breakage and cytotoxicity

1989 • 157 citations

Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide

1989 • 127 citations

Patulin-induced cellular toxicity: A vital fluorescence study

1992 • 79 citations

Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione

1991 • 75 citations

A rapid fluorometric assay to measure neuronal survival in vitro

1993 • 63 citations

Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells

1995 • 61 citations