Identification of T cell subsets and class I and class II antigen expression in islet grafts and pancreatic islets of diabetic BioBreeding/Worcester rats.

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

1967 • 2,783 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 1,046 citations

In Situ Characterization of Autoimmune Phenomena and Expression of HLA Molecules in the Pancreas in Diabetic Insulitis

1985 • 935 citations

Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: Differentiation antigens of rat lymphocytes

1977 • 777 citations

Identification of Ia glycoproteins in rat thymus and purification from rat spleen

1979 • 682 citations

Two subsets of rat T lymphocytes defined with monoclonal antibodies

1980 • 678 citations

Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain.

1981 • 589 citations

Suppression of endogenous avidin-binding activity in tissues and its relevance to biotin-avidin detection systems.

1981 • 545 citations

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

1987 • 451 citations

The Spontaneously Diabetic Wistar Rat: Metabolic and Morphologic Studies

1977 • 409 citations

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases.

1985 • 387 citations

Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus

1982 • 364 citations

Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages.

1985 • 353 citations

Detection of T and B cell antigens hybridoma monoclonal antibodies: a biotin-avidin-horseradish peroxidase method.

1980 • 352 citations

MRC OX‐19: A monoclonal antibody that labels rat T lymphocytes and augments in vitro proliferative responses

1984 • 305 citations

Aberrant expression of Class II major histocompatibility complex molecules by B cells and hyperexpression of Class I major histocompatibility complex molecules by insulin containing islets in Type 1 (insulin-dependent) diabetes mellitus

1987 • 243 citations

Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes

1986 • 214 citations

Spontaneous Diabetes Mellitus: Reversal and Prevention in the BB/W Rat with Antiserum to Rat Lymphocytes

1979 • 212 citations

Neonatal Thymectomy Prevents Spontaneous Diabetes Mellitus in the BB/W Rat

1982 • 193 citations

The roles of host and donor cells in the rejection of skin allografts by T cell‐deprived rats injected with syngeneic T cells

1982 • 190 citations

CYCLOSPORIN PREVENTS DIABETES IN BB WISTAR RATS

1983 • 183 citations

EFFECT OF ORGAN CULTURE ON THE SURVIVAL OF THYROID ALLOGRAFTS IN MICE

1976 • 159 citations

A Repopulation Assay For B and T Lymphocyte Stem Cells Employing Radiation Chimaeras

1981 • 158 citations

Prevention of diabetes in BioBreeding/Worcester rats with monoclonal antibodies that recognize T lymphocytes or natural killer cells.

1986 • 156 citations

Spontaneous diabetes mellitus syndrome in the rat. I. Association with the major histocompatibility complex.

1981 • 155 citations

Passive Transfer of Diabetes in the BB/W Rat

1983 • 155 citations

Pancreas transplantation. An immunohistologic and histopathologic examination of 100 grafts.

1987 • 118 citations

Mechanisms of T Cell-B Cell Interaction

1983 • 117 citations

Pre-diabetes in the spontaneously diabetic BB/E rat: lymphocyte subpopulations in the pancreatic infiltrate and expression of rat MHC class II molecules in endocrine cells

1985 • 111 citations

Spontaneous Diabetes in Rats: Destruction of Islets Is Prevented by Immunological Tolerance

1981 • 101 citations

The Onset and Progression of Pancreatic Insulitis in the Overt, Spontaneously Diabetic, Young Adult BB Rat Studied by Pancreatic Biopsy

1984 • 95 citations

Phenotype of rat natural killer cells defined by monoclonal antibodies marking rat lymphocyte subsets.

1982 • 90 citations

PHENOTYPE AND HISTOLOGICAL DISTRIBUTION OF INTERSTITIAL DENDRITIC CELLS IN THE RAT PANCREAS, LIVER, HEART, AND KIDNEY

1984 • 90 citations

Adoptive transfer of autoimmune diabetes mellitus in biobreeding/Worcester (BB/W) inbred and hybrid rats.

1985 • 87 citations

Islet Cell Surface Antibodies and Lymphocyte Antibodies in the Spontaneously Diabetic BB Wistar Rat

1982 • 87 citations

Lymphocyte transfusions prevent diabetes in the Bio-Breeding/Worcester rat.

1984 • 84 citations

Deficiency of phenotypic cytotoxic-suppressor T lymphocytes in the BB/W rat.

1986 • 83 citations

Two genes required for diabetes in BB rats. Evidence from cyclical intercrosses and backcrosses.

1984 • 78 citations

Spontaneous diabetes mellitus in the Bio-Breeding/Worcester rat. Evidence in vitro for natural killer cell lysis of islet cells.

1986 • 77 citations

Prevention of diabetes mellitus in the BB/W rat with Cyclosporin-A.

1984 • 76 citations

Dynamic time course studies of the spontaneously diabetic BB Wistar rat. III. Light-microscopic and ultrastructural observations of pancreatic islets of Langerhans.

1982 • 76 citations

Endogenously produced Ia antigens within cells of convoluted tubules of rat kidney.

1981 • 75 citations

MRC OX-52: a rat T-cell antigen.

1986 • 73 citations

Transfusions of Whole Blood Prevent Spontaneous Diabetes Mellitus in the BB/W Rat

1983 • 71 citations

Autoantibodies in the BB/W Rat

1982 • 70 citations

Mechanisms of Allograft Rejection: The Roles of Cytotoxic T‐Cells and Delayed‐Type Hypersensitivity

1984 • 70 citations

Spontaneous Diabetes Mellitus in the BB/W Rat: Effects of Glucocorticoids, Cyclosporin-A, and Antiserum to Rat Lymphocytes

1983 • 68 citations

Gastric Parietal Cell and Other Autoantibodies in the BB Rat

1982 • 64 citations

Immune attack on pancreatic islet transplants in the spontaneously diabetic BioBreeding/Worcester (BB/W) rat is not MHC restricted.

1985 • 59 citations

Interactions between T helper cells and dendritic cells during the rat mixed lymphocyte reaction.

1985 • 59 citations

ALTERED DISTRIBUTION OF CLASS I AND CLASS II MHC ANTIGENS DURING ACUTE PANCREAS ALLOGRAFT REJECTION IN THE RAT

1985 • 55 citations

Passive transfer of diabetes from BB/W to Wistar-Furth rats.

1985 • 42 citations

MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS IN THE RAT PANCREAS, ISOLATED PANCREATIC ISLETS, THYROID, AND ADRENAL

1983 • 39 citations

Presence of Pancreatic Hormones in Islet Cells With MHC-Class II Antigen Expression

1987 • 30 citations

Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection.

1980 • 20 citations

T cell hybrids with specificity for islet cell antigens.

1986 • 19 citations

Diabetes mellitus in the BB/W rat. Insulitis in pancreatic islet grafts after transplantation in diabetic recipients.

1986 • 16 citations

Major histocompatibility complex gene product expression on pancreatic beta cells in acutely diabetic BB rats.

1988 • 7 citations