Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Identification of Ia glycoproteins in rat thymus and purification from rat spleen

1979 • 682 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.

1982 • 600 citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

1985 • 440 citations

Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus

1982 • 364 citations

Functions of Rat T‐Lymphocyte Subsets Isolated by Means of Monoclonal Antibodies

1983 • 330 citations

Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens.

1982 • 306 citations

Degradation of basic protein in myelin by neutral proteases secreted by stimulated macrophages: A possible mechanism of inflammatory demyelination

1978 • 276 citations

Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells.

1982 • 261 citations

A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo.

1984 • 257 citations

Sequence Homology Between Certain Viral Proteins and Proteins Related to Encephalomyelitis and Neuritis

1985 • 243 citations

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.

1982 • 237 citations

The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis.

1981 • 215 citations

Immunocytochemical localization of basic protein in major dense line regions of central and peripheral myelin

1982 • 214 citations

Cloned helper T cells can kill B lymphoma cells in the presence of specific antigen: Ia restriction and cognate vs. noncognate interactions in cytolysis

1984 • 152 citations

Acquisition of specific cytotoxic activity by human T4+ T lymphocytes in culture

1984 • 147 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

The role of T cell differentiation markers in antigen-specific and lectin-dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones directed at class I and class II MHC antigens.

1982 • 121 citations

THE MAJOR SITE OF GUINEA‐PIG MYELIN BASIC PROTEIN ENCEPHALITOGENIC IN LEWIS RATS¹²

1977 • 112 citations

Astrocytes: Normal, Reactive and Neoplastic

1984 • 85 citations

Astrocytes: Normal, Reactive, and Neoplastic

1983 • 85 citations

Immunospecific inhibition of nerve conduction by T lymphocytes reactive to basic protein of myelin

1983 • 73 citations

Autoimmune effector cells. V.A monoclonal antibody specific for rat helper T lymphocytes inhibits adoptive transfer of autoimmune encephalomyelitis.

1983 • 69 citations

T lymphocyte lines induce autoimmune encephalomyelitis, delayed hypersensitivity and bystander encephalitis or arthritis

1984 • 53 citations

Cultured human and rat oligodendrocytes and rat schwann cells do not have immune response gene associated antigen (Ia) on their surface

1983 • 44 citations

Identification of a specific HLA DR2 Ia molecule as a restriction element for measles virus-specific HLA class II-restricted cytotoxic T cell clones.

1985 • 42 citations

The lesion of acute experimental autoimmune encephalomyelitis. Isolation and membrane phenotypes of perivascular infiltrates from encephalitic rat brain white matter.

1984 • 36 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. V. Lyt phenotype of cytolytic T lymphocyte precursors reactive against normal and mutant H-2 antigens.

1981 • 31 citations