Effects of diet and of alloxan-diabetes on the activity of branched-chain 2-oxo acid dehydrogenase complex and of activator protein in rat tissues

α-KETO ACID DEHYDROGENASE COMPLEXES, X. REGULATION OF THE ACTIVITY OF THE PYRUVATE DEHYDROGENASE COMPLEX FROM BEEF KIDNEY MITOCHONDRIA BY PHOSPHORYLATION AND DEPHOSPHORYLATION

1969 • 669 citations

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide

1976 • 399 citations

Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones

1971 • 388 citations

Biochemical and Osmotic Properties of Skeletal Muscle Mitochondria

1954 • 289 citations

Isolation of rabbit liver branched chain alpha-ketoacid dehydrogenase and regulation by phosphorylation.

1982 • 172 citations

Coinduction of Rat Liver Branched Chain α-Keto Acid Dehydrogenase Activities

1970 • 171 citations

Subcellular Components

1972 • 137 citations

Reversible phosphorylation of pyruvate dehydrogenase in rat skeletal-muscle mitochondria. Effects of starvation and diabetes

1984 • 120 citations

Diabetes and the control of pyruvate dehydrogenase in rat heart mitochondria by concentration ratios of adenosine triphosphate/adenosine diphosphate, of reduced/oxidized nicotinamide-adenine dinucleotide and of acetyl-coenzyme A/coenzyme A.

1977 • 117 citations

Enzymic determination of branched-chain amino acids and 2-oxoacids in rat tissues. Transfer of 2-oxoacids from skeletal muscle to liver in vivo

1980 • 117 citations

Regulation of the branched chain 2‐oxoacid dehydrogenase kinase reaction

1982 • 116 citations

Purification of rat kidney branched-chain oxo acid dehydrogenase complex with endogenous kinase activity

1982 • 102 citations

Aspects of the regulation of the metabolism of branched-chain amino acids

1977 • 102 citations

Activity state of the branched chain α-ketoacid dehydrogenase complex in heart, liver, and kidney of normal, fasted, diabetic, and protein-starved rats

1983 • 99 citations

Enhanced activity of pyruvate dehydrogenase kinase in rat heart mitochondria in alloxan‐diabetes or starvation

1978 • 85 citations

Inactivation of purified ox kidney branched‐chain 2‐oxoacid dehydrogenase complex by phosphorylation

1981 • 70 citations

Identification of specific subunits of highly purified bovine liver branched-chain ketoacid dehydrogenase

1983 • 66 citations

Inactivation of rat heart branched‐chain 2‐oxoacid dehydrogenase complex by adenosine triphosphate

1978 • 61 citations

Enzyme regulation by reversible phosphorylation : further advances

1984 • 59 citations

Active and inactive forms of branched‐chain 2‐oxoacid dehydrogenase complex in rat heart and skeletal muscle

1980 • 58 citations

Substrate specificity and stabilization by thiamine pyrophosphate of rat liver branched chain α-ketoacid dehydrogenase

1978 • 54 citations

Activities of branched-chain 2-oxo acid dehydrogenase and its components in skin fibroblasts from normal and classical-maple-syrup-urine-disease subjects

1981 • 42 citations

Dephosphorylation and reactivation of phosphorylated purified ox‐kidney branched‐chain dehydrogenase complex by co‐purified phosphatase

1983 • 41 citations

Inactivation of rat liver and kidney branched chain 2‐oxoacid dehydrogenase complex by adenosine triphosphate

1981 • 41 citations

Direct evidence for the inactivation of branched‐chain oxo‐acid dehydrogenase by enzyme phosphorylation

1980 • 33 citations

Activation of phosphorylated branched chain 2‐oxoacid dehydrogenase complex

1982 • 22 citations

Amino acid sequence at the major phosphorylation site on bovine kidney branched‐chain 2‐oxoacid dehydrogenase complex

1983 • 21 citations

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