Possible Autoregulatory Functions of the Secretory Products of Mononuclear Phagocytes

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

1982 • 671 citations

The Macrophage as an Effector Cell

1980 • 628 citations

Enzyme-linked immunoassay (ELISA) for connective tissue components

1980 • 614 citations

Macrophages synthesise and release prostaglandins in response to inflammatory stimuli

1977 • 573 citations

Prostaglandins modulate macrophage Ia expression

1982 • 545 citations

Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.

1978 • 489 citations

Human Blood Monocytes: Stimulators of Granulocyte and Mononuclear Colony Formation in vitro

1972 • 374 citations

Induction of fibroblast chemotaxis by fibronectin. Localization of the chemotactic region to a 140,000-molecular weight non-gelatin-binding fragment.

1981 • 372 citations

Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes.

1980 • 365 citations

Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases.

1981 • 344 citations

Receptors for cold-insoluble globulin (plasma fibronectin) on human monocytes.

1981 • 322 citations

Fibronectin is produced by human macrophages.

1980 • 311 citations

Fibronectin fragment(s) are chemotactic for human peripheral blood monocytes.

1982 • 292 citations

Human alveolar macrophages produce leukotriene B4.

1982 • 278 citations

Specific interaction of murine colony-stimulating factor with mononuclear phagocytic cells.

1980 • 265 citations

Mouse macrophage elastase. Purification and characterization as a metalloproteinase

1981 • 260 citations

Regulation of prostaglandin synthesis and of the selective release of lysosomal hydrolases by mouse peritoneal macrophages

1978 • 255 citations

Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages.

1982 • 247 citations

Platelet‐activating factor and macrophages. I. Evidence for the release from rat and mouse peritoneal macrophages and not from mastocytes

1979 • 244 citations

Macrophage plasminogen activator: induction by concanavalin A and phorbol myristate acetate

1977 • 241 citations

Macrophage-mediated tumor cell killing: regulation of expression of cytolytic activity by prostaglandin E.

1981 • 238 citations

Prostaglandin regulation of macrophage collagenase production.

1977 • 230 citations

Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptors.

1982 • 217 citations

Regulation of macrophage and granulocyte proliferation. Specificities of prostaglandin E and lactoferrin

1979 • 216 citations

Regulation of Macrophage Tumoricidal Function: A Role for Prostaglandins of the E Series

1978 • 214 citations

Cultured human monocytes synthesize and secrete alpha2-macroglobulin.

1977 • 209 citations

Mouse peritoneal macrophages release leukotriene C in response to a phagocytic stimulus.

1980 • 199 citations

Regulation of murine macrophage Ia antigen expression by an immune interferon-like lymphokine: inhibitory effect of endotoxin.

1982 • 193 citations

Induction of prostaglandin E synthesis in normal and neoplastic macrophages: role for colony-stimulating factor(s) distinct from effects on myeloid progenitor cell proliferation.

1979 • 189 citations

The Cell Biology of Inflammation.

1981 • 189 citations

Pharmacological control of prostaglandin and thromboxane release from macrophages

1978 • 187 citations

Biosynthesis of Complement

1976 • 180 citations

Interaction of chemotactic factors with human macrophages: induction of transmembrane potential changes

1977 • 174 citations

Resistance to Murine Tumors Conferred by Chronic Infection with Intracellular Protozoa, Toxoplasma gondii and Besnoitia jellisoni

1971 • 173 citations

Fibronectin-mediated uptake of gelatin-coated latex particles by peritoneal macrophages.

1980 • 172 citations

Mononuclear phagocytes : functional aspects

1980 • 172 citations

Synthesis of the second component of complement by long-term primary cultures of human monocytes.

1976 • 171 citations

Effects of activated complement components on enzyme secretion by macrophages.

1976 • 162 citations

Regulation of the Immune Response — Role of the Macrophage

1980 • 158 citations

The diminished production of arachidonic acid oxygenation products by elicited mouse peritoneal macrophages: possible mechanisms.

1980 • 157 citations

Analysis of macrophage surface receptors. I. Binding of alpha-macroglobulin . protease complexes to rabbit alveolar macrophages.

1979 • 150 citations

Demonstration of a soluble mediator that induces exudates rich in Ia-positive macrophages.

1980 • 148 citations

Synthesis of leukotriene C and other arachidonic acid metabolites by mouse pulmonary macrophages.

1982 • 146 citations

Analysis of macrophage surface receptors. II. Internalization of alpha-macroglobulin . trypsin complexes by rabbit alveolar macrophages.

1979 • 132 citations

Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation.

1977 • 130 citations

Biosynthesis of the First Component of Complement by Human and Guinea Pig Peritoneal Macrophages: Evidence for an Independent Production of the C1 Subunits

1978 • 124 citations

Ability of activated complement components to induce lysosomal enzyme release from macrophages

1976 • 122 citations

Antigen-antibody complexes stimulate the synthesis and release of prostaglandins by mouse peritoneal macrophages

1979 • 122 citations

The Effects of Phagocytosis, Dextran Sulfate, and Cell Damage on PGE1 Sensitivity and PGE1 Production of Macrophages

1978 • 116 citations

Receptors for Maleylated Proteins Regulate Secretion of Neutral Proteases by Murine Macrophages

1982 • 112 citations

Human alveolar macrophage fibronectin: synthesis, secretion, and ultrastructural localization during gelatin-coated latex particle binding

1981 • 110 citations

Limited proteolysis by macrophage elastase inactivates human alpha 1-proteinase inhibitor.

1980 • 107 citations

Subversion of host defense mechanisms by murine tumors. I. A circulating factor that suppresses macrophage-mediated resistance to infection.

1976 • 106 citations

Demonstration of a specific receptor for human C5a anaphylatoxin on murine macrophages.

1982 • 103 citations

Evidence for reutilization of surface receptors for α-macroglobulin · protease complexes in rabbit alveolar macrophages

1980 • 100 citations

Secretion of alpha-2-macroglobulin by human alveolar macrophages

1980 • 98 citations

Production of the second component of complement by human monocytes: stimulation by antigen-activated lymphocytes or lymphokines.

1977 • 97 citations

The induction of macrophage spreading by factor B of the properdin system.

1979 • 96 citations

Biosynthesis of pro-C3, a precursor of the third component of complement.

1977 • 96 citations

Induction of Lysosomal Enzyme Secretion by Alveolar Macrophages in Response to the Purified Complement Fragments C5a and C5a des-arg

1979 • 87 citations

The Cell Biology of Inflammation

1982 • 83 citations

Prostaglandin E1 reversibly induces morphological changes in macrophages and inhibits phagocytosis

1979 • 82 citations

Genetic defect in secretion of complement C5 in mice

1979 • 82 citations

In vitro biosynthesis of cold insoluble globulin (fibronectin) by mouse peritoneal macrophages

1979 • 82 citations

Control of macrophage Ia expression in neonatal mice--role of a splenic suppressor cell.

1982 • 77 citations

C3 cleavage products stimulate release of prostaglandins by human mononuclear phagocytes in vitro.

1983 • 73 citations

In vitro synthesis of some complement components (C1q, C3 and C4) by lymphoid tissues and circulating leucocytes in man.

1975 • 72 citations

Abnormal granulocyte feedback regulation of colony forming and colony stimulating activity-producing cells from patients with chronic myelogenous leukemia

1977 • 72 citations

Metabolic heterogeneity among human monocytes and its modulation by PGE2.

1980 • 69 citations

Effect of RNA and protein synthesis inhibitors on the release of inflammatory mediators by macrophages responding to phorbol myristate acetate

1980 • 68 citations

Biosynthesis of platelet-activating factor (PAF)acether). III. Formation of PAF-acether from synthetic substrates by stimulated murine macrophages.

1982 • 65 citations

Leukotriene B4 biosynthesis by alveolar macrophages

1982 • 61 citations

Distribution of a major surface‐associated glycoprotein, fibronectin, in cultures of adherent cells

1977 • 61 citations

Biosynthetic Defect in Monocytes from Human Beings with Genetic Deficiency of the Second Component of Complement

1975 • 59 citations

Effects of cyclooxygenase inhibitors and prostaglandin E2 on macrophage activation in vitro

1981 • 59 citations

Synthesis of factors D, B and P of the alternative pathway of complement activation, as well as of C3, by guinea-pig peritoneal macrophages in vitro.

1978 • 58 citations

Abnormal responsiveness of granulocyte-macrophage committed colony-forming cells from patients with chronic myeloid leukemia to inhibition by prostaglandin E1.

1980 • 55 citations

Production of the Second (C2) and Fourth (C4) Components of Guinea Pig Complement by Single Peritoneal Cells: Evidence That One Cell May Produce Both Components

1972 • 53 citations

Dextran sulphate: a synthetic activator of C3 via the alternative pathway. I. Influence of molecular size and degree of sulphation on the activation potency.

1975 • 51 citations

Cellular basis for synthesis of the fourth component of guinea-pig complement as determined by a haemolytic plaque technique.

1970 • 47 citations

Potentiation of the primary humoral immune response in vitro by C5a anaphylatoxin.

1982 • 46 citations

Fibronectin: a molecule with remarkable structural and functional diversity

1982 • 41 citations

Synthesis of alpha 1-anti-trypsin by human monocytes.

1983 • 40 citations

Production of C2 by human alveolar macrophages.

1978 • 30 citations

Prostaglandin E2 and prostacyclin elevate cyclic AMP levels in elicited populations of mouse peritoneal macrophages.

1980 • 28 citations

Leukotriene C release by macrophages.

1983 • 28 citations

Secretion of alpha 1-proteinase inhibitor by cultured rat alveolar macrophages.

1981 • 27 citations

Secondary cytotoxic cell response to lymphocytic choriomeningitis virus II. Nature and specificity of effector cells.

1976 • 27 citations

Differential effects of prostaglandins on the antitumor activity of normal and BCG-activated macrophages

1981 • 25 citations

Leukotriene C stimulates prostaglandin release from rat peritoneal macrophages

1981 • 25 citations

Secretion of elastase and alpha-2-macroglobulin by cultured murine peritoneal macrophages: studies on their interaction.

1981 • 25 citations

Lysozyme and Plasminogen Activator: Constitutive and Induced Secretory Products of Mononuclear Phagocytes

1980 • 25 citations

Regulations of macrophage-mediated tumor cell killing by prostaglandins: Comparison of the effects of PGE2 and PGI2

1982 • 25 citations

Prostaglandins and prostaglandin synthetase inhibitors regulate the synthesis of complement components by human monocytes.

1982 • 24 citations

Regulation of prostaglandin and plasminogen activator production by mouse peritoneal macrophages.

1981 • 21 citations

Phorbol myristate acetate induces the secretion of an elastase by populations of resident and elicited mouse peritoneal macrophages

1980 • 21 citations

Cyclic nucleotide metabolism and reactive oxygen production by macrophages

1980 • 19 citations

The Synthesis of Arachidonic Acid Oxygenation Products by Various Mononuclear Phagocyte Populations

1980 • 19 citations

Cyclic AMP-Mediated Modulation of the Production of the Second Component of Human Complement by Monocytes

1981 • 16 citations

Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages

1983 • 15 citations

Effect of in vivo stimulation of mice on the secretion of factor B of the alternative complement pathway by peritoneal macrophages

1977 • 15 citations

Secretory Products of Mononuclear Phagocytes

1982 • 13 citations

Prostaglandin E2 modulation of human monocyte antibody-dependent cell-mediated cytotoxicity against human red blood cells

1982 • 12 citations

Biosynthesis of the Second and Fourth Components of Complement: Inhibition in Vitro by Chemical Carcinogens

1974 • 7 citations