Tryptophan Hydroxylase Regulation Drug-Induced Modifications that Alter Serotonin Neuronal Function

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Tryptophan hydroxylase inhibition: the mechanism by which p-chlorophenylalanine depletes rat brain serotonin.

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Tryptophan hydroxylase. The role of oxygen, iron, and sulfhydryl groups as determinants of stability and catalytic activity.

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Levodopa Toxicity and Apoptosis

1998 • 86 citations

Molecular Mechanism of the Inactivation of Tryptophan Hydroxylase by Nitric Oxide: Attack on Critical Sulfhydryls that Spare the Enzyme Iron Center

1997 • 64 citations

Inactivation of Brain Tryptophan Hydroxylase by Nitric Oxide

1996 • 63 citations

Evidence that the large neutral amino acidl-valine decreases electrically-evoked release of 5-HT in rat hippocampus in vivo

1992 • 50 citations

In Vitro Reactivation of Rat Cortical Tryptophan Hydroxylase Following In Vivo Inactivation by Methylenedioxymethamphetamine

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Involvement of serotonin in clinical features of Parkinson's disease and complications of L-DOPA therapy.

1996 • 48 citations

Expression and Deletion Mutagenesis of Tryptophan Hydroxylase Fusion Proteins: Delineation of the Enzyme Catalytic Core

1996 • 42 citations

3,4-Methylenedioxymethamphetamine-induced acute changes in dopamine transporter function

1998 • 38 citations

Depression in Parkinson's Disease

1996 • 36 citations

Neurotoxicity of Amphetamines and Their Metabolites

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Inhibition of tryptophan hydroxylase by benserazide and other catechols

1991 • 31 citations

Inactivation of Tryptophan Hydroxylase by Nitric Oxide: Enhancement by Tetrahydrobiopterin

1997 • 30 citations

In vitro demonstration of dopamine uptake by neostriatal serotonergic neurons of the rat

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Inhibition of tryptophan hydroxylase by dopamine and the precursor amino acids

1994 • 26 citations

Tryptophan Hydroxylase: Cloning and Expression of the Rat Brain Enzyme in Mammalian Cells

1996 • 25 citations

Methamphetamine-induced decrease in tryptophan hydroxylase activity: role of 5-hydroxytryptaminergic transporters

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Mechanisms Mediating Biogenic Amine Deficits Induced by Amphetamine and Its Congeners

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Dopaminergic transplants alter in vivo activity of tryptophan hydroxylase in the striatum in a rat model of Parkinson's disease

1996 • 8 citations