Interleukin-3 down-regulates its own receptor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture

1974 • 1,037 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

Hematopoietic growth factors.

1987 • 621 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Procedures for the purification of interleukin 3 to homogeneity.

1982 • 428 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

Hierarchical down-modulation of hemopoietic growth factor receptors

1985 • 314 citations

Altered cytosol/membrane enzyme redistribution on interleukin-3 activation of protein kinase C

1985 • 255 citations

Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies

1988 • 248 citations

Interaction of platelet-derived growth factor with its fibroblast receptor. Demonstration of ligand degradation and receptor modulation.

1982 • 239 citations

Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3.

1986 • 238 citations

Hematopoietic growth factors activate the tyrosine phosphorylation of distinct sets of proteins in interleukin-3-dependent murine cell lines.

1988 • 222 citations

Evidence for specific receptors for interleukin 3 on lymphokine-dependent cell lines established from long-term bone marrow cultures.

1984 • 155 citations

Interleukin 3-specific tyrosine phosphorylation of a membrane glycoprotein of Mr 150,000 in multi-factor-dependent myeloid cell lines.

1987 • 129 citations

Recombinant murine GM-CSF from E. coli has biological activity and is neutralized by a specific antiserum.

1985 • 121 citations

Immunological Regulation of Hematopoietic/Lymphoid Stem Cell Differentiation by Interleukin 3

1986 • 115 citations

Purification to apparent homogeneity of a factor stimulating the growth of multiple lineages of hemopoietic cells.

1984 • 108 citations

Effect of haematopoietic cell growth factor on intracellular ATP levels

1983 • 93 citations

Haemopoietic cell growth factor mediates cell survival via its action on glucose transport.

1984 • 92 citations

Identification of the interleukin-3 receptor using an iodinatable, cleavable, photoreactive cross-linking agent.

1986 • 86 citations

Interleukin-3, GM-CSF, and TPA induce distinct phosphorylation events in an interleukin 3-dependent multipotential cell line

1989 • 78 citations

A preliminary report: preparations containing Interleukin-3 (IL-3) promote proliferation of multipotential stem cells (CFUs) in the mouse.

1983 • 40 citations

Down-Regulation of Growth Hormone Releasing Factor Receptors following Continuous Infusion of Growth Hormone Releasing Factor in vivo

1986 • 36 citations

Cloned lines on interleukin 2 producer human T lymphocytes.

1982 • 33 citations

Molecularly cloned and expressed murine T-cell gene product is biologically similar to interleukin-3.

1985 • 22 citations

Regulation of Insulin and Insulin-Like Growth Factor (IGF) Responsiveness by IGFs in Rat Hepatoma Cells*

1986 • 11 citations